(Last updated : 2023-09-21 18:03:45)
  Seigo Terawaki
   Department   Kawasaki Medical School  Kawasaki Medical School, Department of Molecular and Genetic Medicine,
   Position   Assistant Professor with Special Assignment
■ Present specialized field
Immunology, Cell biology, Pathological biochemistry (Key Word:immune response, antigen presentation, autophagy, membrane trafficking, vesicle transport) 
■ Journal
1. 2001/10 Nasal administration of cholera toxin (CT) suppresses clinical signs of experimental autoimmune encephalomyelitis (EAE). 
2. 2002/07 Initiation of NALT organogenesis is independent of the IL-7R, LTbetaR, and NIK signaling pathways but requires the Id2 gene and CD3(-)CD4(+)CD45(+) cells. 
3. 2003/07 PD-1 inhibits antiviral immunity at the effector phase in the liver. 
4. 2005/02 PD-1 blockade inhibits hematogenous spread of poorly immunogenic tumor cells by enhanced recruitment of effector T cells. 
5. 2007/07 Specific and high-affinity binding of tetramerized PD-L1 extracellular domain to PD-1-expressing cells: possible application to enhance T cell function. 
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■ Presentation
1. 2021/12/02 LUBAC ubiquitin ligase complex and linear ubiquitination facilitate cytoplasmic aggregation of amyotrophic lateral sclerosis (ALS)-associated TDP-43 (Speech,Panelist at Symposium/Workshop (Appointed)) 
2. 2021/11/19 HOIPIN-8, a chemical inhibitor for linear ubiquitination, suppresses ALS-related TDP-43 aggregation and inflammatory responses in neuronal cells (Speech,General) 
3. 2020/09/17 Macrophages produce histamine through the interaction with antigen specific Th2 cells. (Poster notice,General) 
4. 2022/11/10 The inhibition of LUBAC mitigates amyotrophic lateral sclerosis-associated TDP-43 aggregation (Poster notice,Panelist at Symposium/Workshop (Applied)) 
5. 2020/06/06 Macrophages produce histamine through the interaction with antigen-specific Th2 cells. (Speech,General) 
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■ Belonging society
1. 2001/04~ Japanese Society for Immunology Link
2. 2018/05~ The Molecular Biology Society of Japan Link