Present specialized field
（Last updated : 2020-07-06 10:42:57）
Present specialized field
Medical biochemistry, Immunology, Pathological biochemistry, Digestive surgery, Connective tissue disease and allergy (Key Word：Host Defense, NADPH oxidase, cellular chemotaxis, Visualization of Cell Function, Cancer metastasis)
Functions of the phagocyte NADPH oxidase and Chronic Granulomatous Disease., Neutrophils: Lifespan, Functions and Roles in Disease.
The NADPH oxidase NOX4 promotes the directed migration of endothelial cells by stabilizing vascular endothelial growth factor receptor 2 protein
Neuroplastinβ-mediated upregulation of solute carrier family 22 member 18 antisense (SLC22A18AS) plays a crucial role in the epithelial-mesenchymal transition, leading to lung cancer cells' enhanced motility.
Retinoic acid dramatically enhanced cytotoxicity of equol against human monoblastic U937 cells, but not against human peripheral neutrophils
DKK3 knockdown confers negative effects on the malignant potency of head and neck squamous cell carcinoma cells via the PI3K/Akt and MAPK signaling pathways.
Monoclonal antibody 7D5 recognizes the R147 epitope on the gp91phox , phagocyte flavocytochrome b558 large subunit.
Upregulation of Mobility in Pancreatic Cancer Cells by Secreted S100A11 Through Activation of Surrounding Fibroblasts.
Critical role of the MCAM-ETV4 axis triggered by extracellular S100A8/A9 in breast cancer aggressiveness.
Melanoma cell adhesion molecule is the driving force behind the dissemination of melanoma upon S100A8/A9 binding in the original skin lesion.
Neuroplastin-b mediates S100A8/A9-induced lung cancer disseminative progression.
Dipeptidyl Peptidase 4 Inhibitors Reduce Hepatocellular Carcinoma by Activating Lymphocyte Chemotaxis in Mice.
b-1,3-Galactosyl-O-Glycosyl-Glycoprotein b-1,6-N-Acetylglucosaminyltransferase 3 Increases MCAM Stability, Which Enhances S100A8/A9-Mediated Cancer Motility.
Convenient methodology for extraction and subsequent selective propagation of mouse melanocytes in culture from adult mouse skin tissue.
NEUROPLASTIN-b MEDIATES S100A8/A9-INDUCED LUNG CANCER DISSEMINATIVE PROGRESSION
Extracellular S100A11 plays a critical role in spread of the fibroblast population in pancreatic cancers
Newly developed anti-S100A8/A9 monoclonal antibody efficiently prevents lung tropic cancer metastasis.
exSSSRs (extracellular S100 Soil Sensor Receptors)-Fc fusion proteins work as prominent decoys to S100A8/A9-induced lung tropic cancer metastasis.
Embigin Promotes Prostate Cancer Progression by S100A4-Dependent and-Independent Mechanisms.
b-1,3-galactosyl-O-glycosyl-glycoprotein b-1,6-N-acetylglucosaminyltransferase 3 increases MCAM stability, which enhances S100A8/A9-mediated cancer motility. Short Title: GCNT3 enhanced S100A8/A9-mediated cancer motility.
DKK3 Overexpression Increases Malignant Properties of Head and Neck Squamous Cell Carcinoma Cells.
Evaluation of pancreatic cancer cell migration with multiple parameters in vitro by using an optical real-time cell mobility assay device
Homodimerisation of the Lymph Vessel Endothelial Receptor LYVE-1 through a Redox-Labile Disulfide is critical for Hyaluronan Binding in Lymphatic Endothelium.
Active Secretion of Dimerized S100A11 Induced by the Peroxisome in Mesothelioma Cells.
MCAM, as a novel receptor for S100A8/A9, mediates progression of malignant melanoma through prominent activation of NF-kB and ROS formation upon ligand binding.
Increase in activated Treg in TIL in lung cancer and in vitro depletion of Treg by ADCC using an anti-human CCR4 mAb (KM2760).
Systematic single cell analysis of migration and morphological changes of human neutrophils over stimulus concentration gradients.
Human skin melanocyte migration towards stromal cell-derived factor-1a demonstrated by optical real-time cell mobility assay: Modulation of their chemotactic ability by a-melanocyte stimulating hormone
Relationship between macrophage differentiation and the chemotactic activity toward damaged myoblast cells
A highly sensitive chemiluminescence assay for superoxide detection and chronic granulomatous disease diagnosis
Role of CC Chemokine Receptor 2 in Bone Marrow Cells in the Recruitment of Macrophages into Obese Adipose Tissue.
Quantitative analysis of eosinophil chemotaxis tracked using a novel optical device - TAXIScan
Rap1a null mice have altered myeloid cell functions suggesting distinct roles for the closely related Rap1a and 1b proteins
Rac GTPase isoform-specific regulation of NADPH oxidase and chemotaxis in murine neutrophils in vivo - Role of the C-terminal polybasic domain
Rac2 regulates neutrophil chemotaxis, superoxide production, and myeloid colony formation through multiple distinct effector pathways
Rac2-deficient murine macrophages have selective defects in superoxide production and phagocytosis of opsonized particles
Chemoattractant-stimulated Rac activation in wild-type and Rac2-deficient murine neutrophils: Preferential activation of Rac2 and Rac2 gene dosage effect on neutrophil functions
Location of the epitope for 7D5, a monoclonal antibody raised against human flavocytochrome b(558), to the extracellular peptide portion of primate gp91(phox)
Phorbol ester-potentiated liposomal transfection to monocytic PLB-985 cells
Eosinophil-specific regulation of gp91(phox) gene expression by transcription factors GATA-1 and GATA-2
An X-linked variant chronic granulomatous disease due to failure in PU.1 binding
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Chemotaxis of human peripheral regulatory T cells is inhibited by LEM
Comparing effects of small molecular weight compounds on proliferation and chemotaxis of pancreatic cancer cells
Heat shock protein 90 (HSP90) inhibitor as a candidate treatment option for gastrointestinal stromal tumor with acquired resistance for conventional receptor tyrosine kinase inhibitors
A new anti-tumor drug for regulating cell dynamics.
Migration of Pancreatic Cancer cell BxPC-3 is suppressed by ROS
CX5461, a selective Polymerase I inhibitor, induces autophagy and suppresses the growth of leukemia cell lines.
The Effect of ROS on the chemotaxis of Inflammatory cells
ROS suppress the cellular chemotaxis
Heat shock protein 90 inhibitors suppress PDGFRA reactivation and other receptor tyrosine kinase activation important in drug resistant gastrointestinal stromal tumors.
Exploring serum factors for evoking and promoting cancer metastasis
HSP90 inhibitor inhibit the activation of proliferation, chemotaxis and EMT in pancreatic cancer cells
HSP90 inhibitor inhibit the activation of multiple kinase pathways and migration of pancreatic
Functional analyses of DKK3 in oral squamous cell carcinoma cell lines
CD26 (DPP-4) as a molecular target for HCC treatment
HSP90 inhibitor inhibit the activation of multiple kinase pathways of pancreatic cancer cells
Suppressing pancreatic cancer metastasis by small molecular compunds
The new molecular target therapy of Hsp90 inhibition in esophageal squamous cell carcinoma
A tryptophan metabolite, kynurenine suppresses chemotaxis of Jurkat T-cells induced by chemokine, SDF-1alpha
Basic research for inhibiting pancreatic cancer metastasis: Gemcitabine vs Dasatinib
Effect of HSP90 inhibitor on proliferation and migration in esophageal squamous cell carcinoma
Antitumor effect of HSP90 inhibitor against esophageal cancer
Evaluation of human melanocyte migration in vitro by a small scale but powerful method utilizing the real-time cell mobility assay device
Formyl peptides and chemokines augment neutrophil accumulation at the inflammation sites whereas lipid mediators support the recruitment.
Effects of PAA and 4-AP on chemotaxis of eosinophil derived from human peripheral blood
Relationship between macrophage differentiation and the chemotactic activity toward damaged muscle cells.
Robust directionality in neutrophil chemotaxis toward the end-target chemoattractant fMLP: an optical approach to the mechanism.
The suppressive effect for chemotaxis and anticancer effect of eicosapentanoic acid in TE-1 cell line.
The robust directionality in neutrophil chemotaxis to fMLP: an optical approach to the mechanism.
Cellular Dynamics Analyzed with TAXIScan - fluorescent imaging of cellular chemotaxis for development of anti-cancer drugs.
Cellular Dynamics Analyzed with TAXIScan – fluorescent imaging of cellular chemotaxis for development of anti-cancer drugs.
TAXISCAN SYSTEM, A UNIQUE TECHNOLOGY FOR FUNCTIONAL ANALYSIS OF LEUKOCYTES.
TAXIScan technology, used for analyses of chemotaxis of leukocytes from lung disease patients and for mast cell degranulation.
Molecular mechanism of macrophage infiltration into obese adipose tissue - Analysis with TAXIScan, a real-time horizontal chemotaxis assay system -
Various physical parameters in the process of chemotaxis tracking using a novel optical device -TAXIScan.
A novel chemotactic assay device TAXIScanTM clarifies different migration pattern of human leukocytes
A novel chemotaxis assay device TAXIScanTM can distinguish difference of migration pattern in human monocytes chemotaxis.
A novel chemotaxis assay device TAXIScanTM can distinguish difference of migration pattern in human neutrophil and monocyte chemotaxis.
A novel chemotaxis assay chamber system TAXIScan; powerful tool for both quantitative and image analysis of host defense function of hematopoteic cells.
Rac2-deficient murine macrophages have selective defects in superoxide production and phagocytosis of opsonized particles.
Rac2-null macrophages have defects in superoxide production and Fcg-R-mediated phagocytosis.
Rac2-null macrophages have defects in superoxide production and Fc-R-mediated
Exogenous Rac protein rescues the functional defects of in Rac2-/- Neutrophils
Dipeptidyl peptidase 4 (DPP4) inhibitor enhances natural killer cell chemotaxis, improving tumor immunity against hepatocellular carcinoma
Kynurenine attenuates chemotaxis of Jurkat T-cells induced by chemokine, SDF-1 alpha
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JAPANESE SOCIETY FOR BACTERIOLOGY
The Japanese Biochemical Society
The Molecular Biology Society of Japan
Japanese Society for Host-Defense Research;JSHDR
Japanese Society for Immunology
International Symposium on Molecular Cell Biology of Macrophages
The Japanese Society of Inflammation and Regeneration
The Japanese Society for Neuroimmunology
The Japanese Society of Immunotoxicology
Japanese Cancer Association.
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