(Last updated : 2020-07-06 10:42:57)
  山内 明
   Department     ,
   Position  
■ Present specialized field
Medical biochemistry, Immunology, Pathological biochemistry, Digestive surgery, Connective tissue disease and allergy (Key Word:Host Defense, NADPH oxidase, cellular chemotaxis, Visualization of Cell Function, Cancer metastasis)  Link
■ BooK
1. 2010   Functions of the phagocyte NADPH oxidase and Chronic Granulomatous Disease., Neutrophils: Lifespan, Functions and Roles in Disease.  Link
■ Journal
1. 2020/07/02 The NADPH oxidase NOX4 promotes the directed migration of endothelial cells by stabilizing vascular endothelial growth factor receptor 2 protein  Link
2. 2020/05/17 Neuroplastinβ-mediated upregulation of solute carrier family 22 member 18 antisense (SLC22A18AS) plays a crucial role in the epithelial-mesenchymal transition, leading to lung cancer cells' enhanced motility.  Link
3. 2020/05/16 Retinoic acid dramatically enhanced cytotoxicity of equol against human monoblastic U937 cells, but not against human peripheral neutrophils  Link
4. 2019/03 DKK3 knockdown confers negative effects on the malignant potency of head and neck squamous cell carcinoma cells via the PI3K/Akt and MAPK signaling pathways.  Link
5. 2018/04 Monoclonal antibody 7D5 recognizes the R147 epitope on the gp91phox , phagocyte flavocytochrome b558 large subunit. 
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■ Presentation
1. 2019/12/11 Chemotaxis of human peripheral regulatory T cells is inhibited by LEM   Link
2. 2019/04/01 Comparing effects of small molecular weight compounds on proliferation and chemotaxis of pancreatic cancer cells   Link
3. 2018/10/22 Heat shock protein 90 (HSP90) inhibitor as a candidate treatment option for gastrointestinal stromal tumor with acquired resistance for conventional receptor tyrosine kinase inhibitors  
4. 2018/10/10 A new anti-tumor drug for regulating cell dynamics.  
5. 2018/09/27 Migration of Pancreatic Cancer cell BxPC-3 is suppressed by ROS  
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■ Belonging society
1. 1997~ JAPANESE SOCIETY FOR BACTERIOLOGY Link
2. 1997~ The Japanese Biochemical Society Link
3. 1997~ The Molecular Biology Society of Japan Link
4. 2003~ Japanese Society for Host-Defense Research;JSHDR Link
5. 2003~ Japanese Society for Immunology Link
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