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Presentation
（Last updated : 2024-11-12 15:47:08）
Kengo Kidokoro
Department
Kawasaki Medical School Kawasaki Medical School, Department of Nephrology and Hypertension,
Position
Assistant Professor
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Present specialized field
Nephrology
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Journal
1.
2024/10/19
Oxidative stress and the role of redox signalling in chronic kidney disease
2.
2024/09
Evaluation of glomerular hemodynamic changes by sodium-glucose-transporter 2 inhibition in type 2 diabetic rats using in vivo imaging
3.
2024/05/01
Investigating the effects of low-level and transient DNA damage on kidney health in a novel mouse model of aging
4.
2024/02
Oxidative stress and the role of redox signalling in chronic kidney disease
5.
2023/10/01
Insights into the regulation of glomerular filtration rate by the Keap1-Nrf2 pathway
6.
2023/09
Activation of the inflammasome drives peritoneal deterioration in a mouse model of peritoneal fibrosis
7.
2023
The deficient of eNOS-NO pathway exacerbates kidney dysfunction
via inflammasome activation in diabetic kidney disease
8.
2022/03
Kidney vascular congestion exacerbates acute kidney injury in mice.
9.
2022/02/01
Evaluation of Neutrophil Dynamics Change by Protective Effect of Tadalafil After Renal Ischemia/Reperfusion Using In Vivo Real-time Imaging.
10.
2021/11
Dipeptidyl peptidase-4 inhibitor linagliptin reduces urinary albumin excretion through the protection of glomerular endothelial function
11.
2021/08/27
Endothelial Dysfunction Accelerates Impairment of Mitochondrial Function in Ageing Kidneys via Inflammasome Activation
12.
2021/05/11
Effect of zinc deficiency on chronic kidney disease progression and effect modification by hypoalbuminemia.
13.
2020/10/02
Essential role and therapeutic targeting of the glomerular endothelial glycocalyx in lupus nephritis
14.
2020/05/01
Klotho is a novel therapeutic target in peritoneal fibrosis via Wnt signaling inhibition.
15.
2020/01
Renoprotective effects of sodium-glucose cotransporter-2 inhibitors and underlying mechanisms.
16.
2019/11
Bardoxolone methyl analog attenuates proteinuria-induced tubular damage by modulating mitochondrial function.
17.
2019/07
Evaluation of Glomerular Hemodynamic Function by Empagliflozin in Diabetic Mice Using In Vivo Imaging.
18.
2019/01
5-Aminolevulinic acid exerts renoprotective effect via Nrf2 activation in murine rhabdomyolysis-induced acute kidney injury.
19.
2018/10/03
The eNOS-NO pathway attenuates kidney dysfunction via suppression of inflammasome activation in aldosterone-induced renal injury model mice.
20.
2017/08
Infiltration of M1, but not M2, macrophages is impaired after unilateral ureter obstruction in Nrf2-deficient mice.
21.
2016/05/23
Feasibility of fluorescence energy transfer system for imaging the renoprotective effects of aliskiren in diabetic mice.
22.
2013/06
Maintenance of endothelial guanosine triphosphate cyclohydrolase I ameliorates diabetic nephropathy.
23.
2013/04
Selective estrogen receptor modulation attenuates proteinuria-induced renal tubular damage by modulating mitochondrial oxidative status.
24.
2013/03
Angiostatin production increases in response to decreased nitric oxide in aging rat kidney.
25.
2012/08
Tacrolimus Induces Glomerular Injury via Endothelial Dysfunction Caused by Reactive Oxygen Species and Inflammatory Change.
26.
2012/06
Endothelial dysfunction promotes the transition from compensatory renal hypertrophy to kidney injury after unilateral nephrectomy in mice.
27.
2011/04
Overexpression of klotho protein modulates uninephrectomy-induced compensatory renal hypertrophy by suppressing IGF-I signals.
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Presentation
1.
2015/11
Intravital multiphoton imaging of podocyte Ca2+ confirms the important role and mechanism of TRPC6 in glomerular pathology （口頭，一般）
2.
2024/05/23
Investigating the effects of low-level and transient DNA damage on kidney health in a novel mouse model of
aging （ポスター掲示，一般）
3.
2023/11/02
Elucidation of the Molecular Mechanism of Albuminuria Improvement by
Nonsteroidal Mineralocorticoid Receptor (MR) Antagonists Focusing on
Podocyte Calcium (Ca2+) Dynamics （ポスター掲示，一般）
4.
2022/10/15
Examination of albuminuria reduction effect through improvement of eNOS uncoupling by SGLT2 in type 2 diabetic mice （ポスター掲示，一般）
5.
2022/10/15
Glomerular Hemodynamic Changes with SGLT2 Inhibition in Type 2 Diabetic Rats Using In Vivo Imaging （ポスター掲示，一般）
6.
2022/10/15
Regulatory mechanism of glomerular filtration rate by the Keap1/Nrf2 pathway （ポスター掲示，一般）
7.
2021/11/04
Elucidation of glomerular hemodynamic changes by SGLT2 Inhibitors and ARBs in a type II diabetic animal model
using in vivo imaging （ポスター掲示，一般）
8.
2021/02/28
Evaluation of glomerular hemodynamic changes by SGLT2 inhibitor and ARB in type 2 diabetic rats using in vivo imaging （口頭，一般）
9.
2020/10/19
Effect of Zinc Deficiency on CKD Progression and Effect Modification by Hypoalbuminemia. （ポスター掲示，一般）
10.
2020/10/19
eNOS/NO Signaling Attenuates Progression of Age-Related Kidney Diseases via Suppression of Inflammasome. （ポスター掲示，一般）
11.
2020/10/02
DEFICIENT OF ENOS/NO PATHWAY PROMOTES AKI TO CKD TRANSITION AFTER ISCHEMIC REPERFUSION （ポスター掲示，一般）
12.
2020/10/02
ENOS/NO SIGNALLING ATTENUATES GLOMERULAR INJURY IN DIABETIC MICE VIA SUPPRESSION OF INFLAMMASOME ACTIVATION （ポスター掲示，一般）
13.
2020/10/02
EVALUATION OF THE MECHANISM OF GLOMERULAR ARTERIOLE CHANGES BY SGLT2 INHIBITION IN TYPE 2 DIABETIC RATS （ポスター掲示，一般）
14.
2020/10/02
THE EFFECTS OF SGLT2 INHIBITORS ON GLOMERULAR HYPERFILTRATION AND OXIDATIVE STRESS IN MICE WITH DIABETIC KIDNEY DISEASE （ポスター掲示，一般）
15.
2020/09/27
Sodium–glucose cotransporter 2 inhibitors as a novel therapy for diabetic kidney disease: Therapeutic implications . （口頭）
16.
2020/09/25
Elucidation of the pathophysiological mechanisms in diabetic kidney disease using intravital imaging. （口頭，シンポジウム・ワークショップ パネル（その他））
17.
2020/06/07
Effects of sodium–glucose cotransporter 2 inhibitor, canagliflozin on glomerular hyperfiltration and oxidative stress in mice with type 2 diabetes （口頭，一般）
18.
2020/06/07
EVALUATION OF GLOMERULAR HEMODYNAMIC CHANGES BY SGLT2 INHIBITION IN TYPE 2 DIABETIC RATS USING IN VIVO IMAGING TECHNIQUES （口頭，一般）
19.
2020/06/07
KEAP1/NRF2 PATHWAY REGULATES GFR BY INCREASING THE GLOMERULAR EFFECTIVE AREA WITHOUT AFFECTING THE AFFERENT/EFFERENT ARTERIOLE RATIO （ポスター掲示）
20.
2020/02/15
Zinc deficiency is a risk factor for chronic kidney disease progression （口頭，一般）
21.
2019/11/09
Endothelial Nitric Oxide Synthase/Nitric Oxide Pathway Underlies the Mechanisms of AKI to CKD Transition via Prolonged Activation of the Wnt/β-Catenin Pathway （ポスター掲示，一般）
22.
2019/11/08
Clarification of the mechanism of acute GFR change by SGLT2 inhibition using in vivo imaging technique （ポスター掲示，一般）
23.
2019/11/08
Clarification of the Mechanism of Acute GFR Change by SGLT2 Inhibition with In Vivo Imaging Technique （ポスター掲示，一般）
24.
2019/11/07
Activation of the Keap1/Nrf2 Pathway Increases GFR by Increasing Glomerular Effective Filtration Area Without Affecting the Afferent/Efferent Arteriole Ratio （ポスター掲示，一般）
25.
2019/06/13
Investigation of the suppressive effects of an SGLT2 inhibitor on glomerular hyperfiltration and oxidative stress in mice with diabetic kidney disease. （ポスター掲示，一般）
26.
2019/04/12
Bardoxolone methyl analog attenuates proteinuria-induced tubular damege by modulating mitochondrial function. （ポスター掲示，一般）
27.
2019/04/12
Effect of uremic toxin-indoxcyl sulfate on intestinal defensin expression in renal failure mice. （ポスター掲示，一般）
28.
2019/04/12
Evaluation of the diabetic glomerular hemodynamics by SGLT2 inhibitor empagliflozin using in vivo imaging. （ポスター掲示，一般）
29.
2018/10/25
Endothelial Dysfunction Exacerbates Renal Tubular Cell Injury Through Inflammasome Activation in a Hypertensive Mouse Model （ポスター掲示，一般）
30.
2018/06/23
Evaluation of Glomerular Hemodynamic Function by Empagliflozin in Diabetic Mice Using In Vivo Imaging. （口頭，一般）
31.
2018/05/25
EVALUATION OF THE GLOMERULAR HEMODYNAMICS BY THE SGLT2 INHIBITOR EMPAGLIFLOZIN
USING IN VIVO IMAGING （ポスター掲示，一般）
32.
2018/05/25
NRF2 ACTIVATOR, RTADH404, ATTENUATES RENAL TUBULAR INJURY VIA MITOCHONDRIAL
PROTECTION IN NEPHROTIC MODEL MICE. （ポスター掲示，一般）
33.
2018/02/22
5-aminolevulinic acid exerts renoprotective effect via Nrf2 activation in rhabdomyolysis-induced acute kidney injury . （ポスター掲示，一般）
34.
2018/02/22
A case of copper deficiency-induced pancytopenia with maintenance hemodialysis outpatient treated with polaprezinc . （ポスター掲示，一般）
35.
2018/02/22
Effect of single pill-based combination therapy on variability of home blood pressure in hypertensive outpatients. （ポスター掲示，一般）
36.
2018/02/22
eNOS -NO signaling attenuates renal fibrosis via suppression of catenin signaling. （ポスター掲示，一般）
37.
2018/02/22
Evaluation of the glomerular hemodynamics alterations by SGLT2 inhibitor Empagliflozin using in vivo imaging. （ポスター掲示，一般）
38.
2018/02/22
Non-purine selective xanthine oxidase inhibitor ameliorates glomerular endothelial injury in Ins2Akita diabetic mice. （ポスター掲示，一般）
39.
2018/02/22
RTAdh404 attenuates renal inflammation and fibrosis via mitochondrial protection in ICGN mice. （ポスター掲示，一般）
40.
2018/02/22
The association of microbiota alteration and intestinal barrier function in chronic renal failure mice. （ポスター掲示，一般）
41.
2018/02/22
The eNOS/NO signaring attenuates glomerular injury in diabetic mice via suppression of inflammasome activation. （ポスター掲示，一般）
42.
2018/02/10
Evaluation of the glomerular hemodynamics alterations by SGLT2 inhibitor Empagliflozin in diabetic mice using in vivo imaging. （ポスター掲示，一般）
43.
2017/11/03
Deficient of Endothelial Function Exacerbates NLRP3-Inflammasome Activation in Podocyte of Diabetic Nephropathy （ポスター掲示，一般）
44.
2017/11/02
Evaluation of the Reno-Protective Effects of Empagliflozin in Diabetic Nephropathy Using In Vivo Imaging （ポスター掲示，一般）
45.
2017/09/15
Evaluation of the effect of empagliflozin on improving hyperfiltration in diabetic nephropathy （口頭，一般）
46.
2016/09/27
Feasibility of Fluorescence Energy Transfer System for Imaging the Renoprotective Effects of Aliskiren in Diabetic Mice. （ポスター掲示，一般）
47.
2016/09/19
Renoprotective Effect of 5-Aminolevulinic Acid in Rhabdomyolysis-Induced Acute Kidney Injury （口頭，一般）
48.
2016/06/17
Intravital imaging of TRPC6 - mediated podocyte calcium changes in glomerular pathology （口頭，シンポジウム・ワークショップ パネル（指名））
49.
2016/05/31
Feasibility of Fluorescence Energy Transfer System for Imaging the Renoprotective Effects of Aliskiren in Diabetic Mice. （ポスター掲示）
50.
2015/09/25
Visualization of in vivo renin activity and its application to study the pathogenetic mechanisms of diabetic nephropathy （ポスター掲示，一般）
51.
2014/11/15
In Vivo Serial Multiphoton Imaging of the Early Changes in Glomerular Structure and Function in Nephrotic NEP25/Podocin-Confetti Mice （口頭，一般）
52.
2014/09/09
Development of a Novel Technique to Visualize in Vivo Renin Activity and Assess its Use in the Study of the Pathogenesis of Diabetic Nephropathy. （ポスター掲示，一般）
53.
2013/10/24
Comparison of Combination Therapy with Irbesartan/Amlodipine and Irbesartan/Cilnidipine for Attenuation of Albuminuria in Rats with Streptozotocin Induced Diabetic Nephropathy. （ポスター掲示，一般）
54.
2013/10/24
Investigation for the Mechanisms of Anti-albuminuic Effects of T Type Ca-channel Blocker through Amelioration of eNOS Uncoupling. （口頭，一般）
55.
2013/06/02
Implications of Inflammasome-Activation in Macrophage on the Development of Renal Interstitial Inflammation and Fibrosis in Mice. （ポスター掲示，一般）
56.
2013/06/01
Development of Novel Technique to Visualize in vivo Renin Activity and Analysis of Reno-Protective Actions of Renin Inhibitor in Diabetic Nephropathy. （ポスター掲示，一般）
57.
2013/06/01
Rosuvastatin Maintain Glomerular Endothelial Surface layer Through Nrf2 Activation in Mouse Diabetic Nephropathy. （ポスター掲示，一般）
58.
2013/04/24
Enhanced apoptosis may lead to fewer nephrons in Japanese quail subjected to reduced nutrition during development. （ポスター掲示，一般）
59.
2012/11/07
Preservation of Endothelial GTP Cyclohydrolase I Activity and Improvement of Renal Nitric Oxide Availability Prevent the Development of Albuminuria in Diabetes （ポスター掲示，一般）
60.
2012/11/02
Klotho Attenuates Inflammation of Adipose Tissue and Development of Insulin Resistance in High-Fat Induced Obese Mice. （ポスター掲示，一般）
61.
2012/11/02
Stimulation of Soluble Guanylate Cyclase Attenuates Epithelial-Mesenchymal Transition of the Peritoneal Membrane and Prevent the Development of Peritoneal Fibrosis. （口頭，一般）
62.
2012/11/01
Development of a Novel Technique to Visualize In Vivo Renin Activity and Analysis of the Renoprotective Actions of a Renin Inhibitor. （ポスター掲示，一般）
63.
2012/07/20
eNOS-sGC pathway suppresses renal fibrosis via interruption of the Wnt-beta-catenin pathway in UUO mice. （ポスター掲示，一般）
64.
2012/05/25
Endothelial Cell Interacted with Podocyte and Mesangial Cells Via NAD(P)H Oxidase. （ポスター掲示，一般）
65.
2012/05/25
Preservation of Endothelial GTP Cyclohydrolase I Activity and Improvement of Renal Nitric Oxide Availability Prevent the Development of Diabetic Nephropathy （ポスター掲示，一般）
66.
2011/11/12
Low-Dose Erythropoietin Increases Superoxide Production in Normal Rat Aorta and Endothelial Cells （ポスター掲示，一般）
67.
2011/11/11
Implications of Oxidative Stress Derived from Endothelial NAD(P)H Oxdase in the Development of Diabetic Nephropathy （ポスター掲示，一般）
68.
2011/11/10
Preservation of Endothelial GTP Cyclohydrolase I Activity by Metformin Prevent the Development of Diabetic Nephropathy （ポスター掲示，一般）
69.
2011/11/07
Role of GTP cyclohydrolase-1 as a novel therapeutic target of diabetic nephropathy （口頭，一般）
70.
2011/09/22
Role of GTP cyclohydrolase-1 as a novel therapeutic target of diabetic nephropathy. （ポスター掲示，一般）
71.
2011/07/16
Comparison of combination therapy of olmesartan plus azelnidipine or hydrochlorothiazide on renal and vascular damage in SHR/NDmcr-cp rats. （ポスター掲示，一般）
72.
2011/04/10
Cyclic GMP Dependent Protein Kinase-Akt Pathway is Essential for Compensatory Renal Hypertrophy and Maintenance Renal Function After Unilateral Nephrectomy. （ポスター掲示，一般）
73.
2011/04/10
Over-Expression of Endothelial GTP Cyclohydrolase-ⅠAmeliorates Mouse Diabetic Glomerulopathy. （ポスター掲示，一般）
74.
2010/11/18
Over-Expression of GTP Cyclohydrolase-ⅠRetards Development of Albuminuria and Ameliorates Renal Injuries in Diabetes （ポスター掲示，一般）
75.
2010/09/26
Eplerenone improved renal and vascular injuries in Zucker obese rats fed high-protein diet （ポスター掲示，一般）
76.
2010/06/27
Mechanisms of acute tacrolims-induced nephrotoxicity and the renoprotective effects of telmisartan （ポスター掲示，一般）
77.
2010/06/26
Calcium channel blokers azelnidipine but not amlodipine reduce glomerular damages in Dahl salt -sansitive rats by suppression of sympathetic nerve system （ポスター掲示，一般）
78.
2010/06/26
Establishment of new blood purification system in renal failure rats using a small dialyzer （ポスター掲示，一般）
79.
2010/06/26
Renal denervation reduces glomerular superoxide production and protects from gromerular injury in Dahl salt-sensitive rats （ポスター掲示，一般）
80.
2010/06/15
Renal denervation attenuates glomerular schrelosis by suppressing NAD(P)H oxidase activity in Dahl salt-sensitive rats （ポスター掲示，一般）
81.
2010/05/15
Effects of eplerenone to renal and vascular injuries in Zucker obese rats fed high-protein diet （ポスター掲示，一般）
82.
2010/04/17
ARB/CCB combination therapy suppressed oxidative stress compared with ARB/HCTZ combination therapy in glomeruli and aorta of metabolic syndrome model rats （ポスター掲示，一般）
83.
2010/04/17
Glomerular endothelial glycocalyx was decreases by reactive oxygen species in Zucker obese fatty rat （ポスター掲示，一般）
84.
2009/10/30
Increased Angiostatin Production by Nitric Oxide Reduction Induces Tubulointerstitial Damage in Rat Aging Kidney （ポスター掲示，一般）
85.
2009/10/29
Overexpression of Klotho Protein Inhibits Uninephrectmy Induced Compensatory renal Hypertrophy by Suppressing Insulin Like Growth Factor-1 Signals （口頭，一般）
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