(Last updated : 2025-05-27 11:02:47)
  Nagio Takigawa
   Department   Kawasaki Medical School  Kawasaki Medical School, Department of General Internal Medicine 4,
   Position   Professor
■ Present specialized field
Respiratory medicine, Molecular biology, General internal medicine (Key Word:drug resistance, molecular target, chemotherapy, immunotherapy) 
■ BooK
1. 2015/08   Cancer Stem Cells and Chemoresistance, Stem Cells in Modeling Human Genetic Diseases 
2. 2011/09   “Hairy morphology” of hairy cell leukemia-Japanese variant may disappear under specific conditions, BloodMed 
■ Journal
1. 2025/04/25 Plasma cell-free DNA methylation profile before afatinib treatment is associated with progression-free and overall survival of patients with epidermal growth factor receptor gene mutation-positive non-small cell lung cancer 
2. 2025/03/19 Establishment and characterization of novel patient-derived esophageal tumoroids with long-term cultivability 
3. 2025/01/31 The heterogeneity in oligoprogression and stereotactic body radiation therapy  Link
4. 2024/12 Efficacy of immune checkpoint inhibitors according to programmed cell death-ligand 1 expression in patients with non-small cell lung cancer and brain metastasis: A real-world prospective observational study 
5. 2024/11/16 Four cases with FUS/CHOP fusion gene products positive myxoid liposarcoma responding effectively to trabectedin monotherapy 
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■ Presentation
1. 2023/10/11 A novel molecular target, superoxide dismutase 1, in ALK inhibitor-resistant lung cancer cells, detected through proteomic analysis (Poster notice,General) 
2. 2019/09 A randomized trial of sodium alginate prevention of radiation-induced esophagitis in patients with locally advanced NSCLC receiving concurrent chemoradiotherapy: OLCSG1401 (Poster notice) 
3. 2019/04/02 Development of an integrated CRISPR interference system targeting Np63 to treat lung and esophageal squamous cell carcinoma. (Poster notice,General) 
4. 2018/09/28 Targeted silencing of SOX2 by an ATF showed antitumor effect in lung and esophageal squamous cell carcinoma (Poster notice) 
5. 2018/07/20 Patients with osteosarcoma and soft tissue sarcoma tend to become cancer refugees in
Japanese regional cities (Poster notice) 
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