(Last updated : 2024-11-18 09:32:19)
  Nagio Takigawa
   Department   Kawasaki Medical School  Kawasaki Medical School, Department of General Internal Medicine 4,
   Position   Professor
■ Present specialized field
Respiratory medicine, Molecular biology, General internal medicine (Key Word:drug resistance, molecular target, chemotherapy, immunotherapy) 
■ BooK
1. 2015/08   Cancer Stem Cells and Chemoresistance, Stem Cells in Modeling Human Genetic Diseases 
2. 2011/09   “Hairy morphology” of hairy cell leukemia-Japanese variant may disappear under specific conditions, BloodMed 
■ Journal
1. 2024/07/19 The combined inhibition of SLC1A3 and glutaminase in osimertinib-resistant EGFR mutant cells  Link
2. 2024/06/03 Transforming tumoroids derived from ALK‑positive pulmonary
adenocarcinoma to squamous cell carcinoma in vivo 
Link
3. 2024/04/28 Patient-derived tumoroid models of pulmonary large-cell neuroendocrine carcinoma: a promising tool for personalized medicine and developing novel therapeutic strategies  Link
4. 2024/04/17 Establishment and characterization of novel high mucus‑producing lung tumoroids derived from a patient with pulmonary solid adenocarcinoma  Link
5. 2024/03/05 Endobronchial Ultrasonography With Guide Sheath for the Diagnosis of Peripheral Pulmonary Lesions in Japan: A Literature Review  Link
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■ Presentation
1. 2023/10/11 A novel molecular target, superoxide dismutase 1, in ALK inhibitor-resistant lung cancer cells, detected through proteomic analysis (Poster notice,General) 
2. 2019/09 A randomized trial of sodium alginate prevention of radiation-induced esophagitis in patients with locally advanced NSCLC receiving concurrent chemoradiotherapy: OLCSG1401 (Poster notice) 
3. 2019/04/02 Development of an integrated CRISPR interference system targeting Np63 to treat lung and esophageal squamous cell carcinoma. (Poster notice,General) 
4. 2018/09/28 Targeted silencing of SOX2 by an ATF showed antitumor effect in lung and esophageal squamous cell carcinoma (Poster notice) 
5. 2018/07/20 Patients with osteosarcoma and soft tissue sarcoma tend to become cancer refugees in
Japanese regional cities (Poster notice) 
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