(Last updated : 2025-08-22 12:21:32)
  Nagio Takigawa
   Department   Kawasaki Medical School  Kawasaki Medical School, Department of General Internal Medicine 4,
   Position   Professor
■ Present specialized field
Respiratory medicine, Molecular biology, General internal medicine (Key Word:drug resistance, molecular target, chemotherapy, immunotherapy) 
■ BooK
1. 2015/08   Cancer Stem Cells and Chemoresistance, Stem Cells in Modeling Human Genetic Diseases 
2. 2011/09   “Hairy morphology” of hairy cell leukemia-Japanese variant may disappear under specific conditions, BloodMed 
■ Journal
1. 2025/07/28 Utility of ultrasound-guided transbronchial needle biopsy using an acquire needle in the diagnosis of chest and mediastinal diseases 
2. 2025/05/31 Plasma biomarkers for afatinib monotherapy in EGFR-mutated non-small cell lung cancer: Novel insights from companion genomics analysis of the EXTRA study 
3. 2025/04/25 Plasma cell-free DNA methylation profile before afatinib treatment is associated with progression-free and overall survival of patients with epidermal growth factor receptor gene mutation-positive non-small cell lung cancer 
4. 2025/03/19 Establishment and characterization of novel patient-derived esophageal tumoroids with long-term cultivability 
5. 2025/01/31 The heterogeneity in oligoprogression and stereotactic body radiation therapy  Link
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■ Presentation
1. 2023/10/11 A novel molecular target, superoxide dismutase 1, in ALK inhibitor-resistant lung cancer cells, detected through proteomic analysis (ポスター掲示,一般) 
2. 2019/09 A randomized trial of sodium alginate prevention of radiation-induced esophagitis in patients with locally advanced NSCLC receiving concurrent chemoradiotherapy: OLCSG1401 (ポスター掲示) 
3. 2019/04/02 Development of an integrated CRISPR interference system targeting Np63 to treat lung and esophageal squamous cell carcinoma. (ポスター掲示,一般) 
4. 2018/09/28 Targeted silencing of SOX2 by an ATF showed antitumor effect in lung and esophageal squamous cell carcinoma (ポスター掲示) 
5. 2018/07/20 Patients with osteosarcoma and soft tissue sarcoma tend to become cancer refugees in
Japanese regional cities (ポスター掲示) 
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