Faculty Information - Tamaki Sasaki

Current specialization

Publications

Journal Articles

Presentations

（Last updated : 2025-05-15 13:28:12）

Tamaki Sasaki
Department Kawasaki Medical School Kawasaki Medical School, Department of General Medicine,

Position Professor with Special Assignment

■ Current specialization

Nephrology, Others

■ Publications

2017/01

Clearance Gap: Does It Really Matter for the Evaluation of Vascular Access Function?, Scientific Aspects of Dialysis Therapy (in Contributions to Nephrology)

■ Journal Articles

1.	2024/11/02	ASK-1 activation exacerbates kidney dysfunction via increment of glomerular permeability and accelerates cellular aging in diabetic kidney disease model mice
2.	2024/11	Effects of Beraprost on Intestinal Microcirculation and Barrier Function in a Mouse Model of Renal Failure. inpress
3.	2024/09	Evaluation of glomerular hemodynamic changes by sodium-glucose-transporter 2 inhibition in type 2 diabetic rats using in vivo imaging
4.	2024/03/13	Mathematical expansion and clinical application of chronic kidney disease stage as vector field
5.	2024/01/18	New marker for chronic kidney disease progression and mortality in medical-word virtual space.
6.	2024/01/09	A case series of Fabry diseases with CKD in Japan.
7.	2023/12/19	IL-1β may be an indicator of peritoneal deterioration after healing of peritoneal dialysis-associated peritonitis
8.	2023/10/01	Insights into the regulation of glomerular filtration rate by the Keap1-Nrf2 pathway
9.	2023/10	Insights into the Regulation of GFR by the Keap1-Nrf2 Pathway.
10.	2023/09	Activation of the inflammasome drives peritoneal deterioration in a mouse model of peritoneal fibrosis
11.	2023/09	Activation of the inflammasome drives peritoneal deterioration in a mouse model of peritoneal fibrosis.
12.	2023/06	The Impact of Potassium Binders on Mortality in Patients with Hyperkalemia: A Single-Center Study
13.	2023/01/25	Drug-induced acute kidney injury
14.	2023	The deficient of eNOS-NO pathway exacerbates kidney dysfunction via inflammasome activation in diabetic kidney disease
15.	2022/03/23	A case of pleuroperitoneal communication during long-term steroid therapy for dermatomyositis
16.	2021/11	Dipeptidyl peptidase-4 inhibitor linagliptin reduces urinary albumin excretion through the protection of glomerular endothelial function
17.	2021/08/27	Endothelial Dysfunction Accelerates Impairment of Mitochondrial Function in Ageing Kidneys via Inflammasome Activation
18.	2021/08	A rare case of amyloid light-chain amyloidosis with bilateral perirenal hematoma shortly after initiation of peritoneal dialysis.
19.	2021/07/14	Case reports of pregnancies complicated with kidney disease and their fetal prognosis
20.	2021/06	Renal cell carcinoma sharply captured by imaging technology at an early stage in a hemodialysis patient: Usefulness of noninvasive monochrome superb microvascular imaging
21.	2021/05/11	Effect of zinc deficiency on chronic kidney disease progression and effect modification by hypoalbuminemia.
22.	2020/11/01	Non-purine selective xanthine oxidase inhibitor ameliorates glomerular endothelial injury in InsAkita diabetic mice.
23.	2020/05/25	Impact of heavy rains of 2018 in western Japan: disaster-induced health outcomes among the population of Innoshima Island
24.	2020/05/01	Klotho is a novel therapeutic target in peritoneal fibrosis via Wnt signaling inhibition.
25.	2020/05	Impact of heavy rains of 2018 in western Japan: disaster-induced health outcomes among the population of Innoshima Island
26.	2019/11	Bardoxolone methyl analog attenuates proteinuria-induced tubular damage by modulating mitochondrial function.
27.	2019/07	Evaluation of Glomerular Hemodynamic Function by Empagliflozin in Diabetic Mice Using In Vivo Imaging.
28.	2019/01	5-Aminolevulinic acid exerts renoprotective effect via Nrf2 activation in murine rhabdomyolysis-induced acute kidney injury.
29.	2018/10/03	The eNOS-NO pathway attenuates kidney dysfunction via suppression of inflammasome activation in aldosterone-induced renal injury model mice.
30.	2018/01	Proteinuria in neuronal intranuclear inclusion disease
31.	2017/08	Infiltration of M1, but not M2, macrophages is impaired after unilateral ureter obstruction in Nrf2-deficient mice.
32.	2017/06	Colchicine attenuates renal fibrosis in a murine unilateral ureteral obstruction model.
33.	2017/06	Restricted nutrition-induced low birth weight, low number of nephrons and glomerular mesangium injury in Japanese quail.
34.	2016/10	Klotho attenuates renal hypertrophy and glomerular injury in Ins2Akita diabetic mice.
35.	2016/05/23	Feasibility of fluorescence energy transfer system for imaging the renoprotective effects of aliskiren in diabetic mice.
36.	2016/02	Prevalence of gastroesophageal reflux disease symptoms and effects of esomeprazole on the quality of life related to reflux and dyspepsia in patients on maintenance hemodialysis.
37.	2016/01	Activation of endothelial NAD(P)H oxidase accelerates early glomerular injury in diabetic mice.
38.	2015/12	Severe hyperkalemia following ileostomy not colostomy in a patient undergoing chronic hemodialysis
39.	2015/09	Excess aldosterone is a critical danger signal for inflammasome activation in the development of renal fibrosis in mice.
40.	2015/09	Relationship between vascular function indexes, renal arteriolosclerosis, and renal clinical outcomes in chronic kidney disease.
41.	2015/08	Deficiency of endothelial nitric oxide signaling pathway exacerbates peritoneal fibrosis in mice.
42.	2015/05	Combination Irbesartan/Amlodipine versus Irbesartan/Cilnidipine for Attenuation of Albuminuria in Rats with Streptozotocin-Induced Diabetic Nephropathy
43.	2014/12	Nuclear Factor Erythroid 2-Related Factor 2 is Activated by Rosuvastatin via p21cip1 Upregulation in Endothelial Cells
44.	2014/05/10	［Acute kidney injury: progress in diagnosis and treatments. Topics: IV. Pathophysiology and treatments; 4. Association of CKD and acute kidney injury］
45.	2014/02	Angiotensin II Regulates Islet Microcirculation and Insulin Secretion in Mice.
46.	2014	Hypertension promotes islet morphological changes with vascular injury on pre-diabetic status in SHRsp rats.
47.	2013/06	Maintenance of endothelial guanosine triphosphate cyclohydrolase I ameliorates diabetic nephropathy.
48.	2013/04	Erythropoietin-producing tubercle granuloma in a hemodialysis patient.
49.	2013/04	Selective estrogen receptor modulation attenuates proteinuria-induced renal tubular damage by modulating mitochondrial oxidative status.
50.	2013/03	Angiostatin production increases in response to decreased nitric oxide in aging rat kidney.
51.	2012/12	Establishment of a blood purification system for renal failure rats using small-size dialyzer membranes.
52.	2012/12	Renal disease in the elderly and the very elderly Japanese: analysis of the Japan Renal Biopsy Registry (J-RBR).
53.	2012/08	Tacrolimus Induces Glomerular Injury via Endothelial Dysfunction Caused by Reactive Oxygen Species and Inflammatory Change.
54.	2012/06	Endothelial dysfunction promotes the transition from compensatory renal hypertrophy to kidney injury after unilateral nephrectomy in mice.
55.	2012/05	[Chronic kidney disease (CKD)--recent progress. Topics: VI. Chronic kidney disease (CKD) and associated disorders: 9. Kidney and senescence]
56.	2012/03	Azelnidipine attenuates glomerular damage in Dahl salt-sensitive rats by suppressing sympathetic nerve activity.
57.	2011/08	Japan Renal Biopsy Registry: the first nationwide, web-based, and prospective registry system of renal biopsies in Japan.
58.	2011/04	Overexpression of klotho protein modulates uninephrectomy-induced compensatory renal hypertrophy by suppressing IGF-I signals.
59.	2011/02	Mitochondrial damage-induced impairment of angiogenesis in the aging rat kidney.
60.	2011	A novel mutation ApoE2 Kurashiki (R158P) in a patient with lipoprotein glomerulopathy.
61.	2011	Comparison of Combination Therapy of Olmesartan plus Azelnidipine or Hydrochlorothiazide on Renal and Vascular Damage in SHR/NDmcr-cp Rats.
62.	2010/11	[Alterations of mesangial cell and matrix]
63.	2010/11	Histopathological manifestations of membranoproliferative glomerulonephritis and glomerular expression of plasmalemmal vesicle-associated protein-1 in a patient with polycythemia vera
64.	2010/09	Deterioration of glomerular endothelial surface layer induced by oxidative stress is implicated in altered permeability of macromolecules in Zucker fatty rats.
65.	2010/07	Clear Correlation of Tetrahydrobiopterin with Nitric Oxide Bioavailability in Continuous Ambulatory Peritoneal Dialysis
66.	2010/02	In vivo visualization of glomerular microcirculation and hyperfiltration in streptozotocin-induced diabetic rats.
67.	2010/02	Telmisartan improves endothelial dysfunction and renal autoregulation in Dahl salt-sensitive rats
68.	2009/12	Azelnidipine exerts renoprotective effects by improvement of renal microcirculation in angiotensin II infusion rats.
69.	2009/10	Tonsillectomy and steroid pulse (TSP) therapy for patients with IgA nephropathy: a nationwide survey of TSP therapy in Japan and an analysis of the predictive factors for resistance to TSP therapy.
70.	2009/09	Reactive oxygen species mediate compensatory glomerular hypertrophy in rat uninephrectomized kidney
71.	2009/06	Zinc deficiency anemia and effects of zinc therapy in maintenance hemodialysis patients.
72.	2009/05	High dietary protein intake induces endothelial dysfunction in uninephrectomized rats
73.	2009/01	Direct Measurement of Nitric Oxide Concentration in CAPD Dialysate
74.	2008/12	Angiotensin II type 1 receptor blocker ameliorates uncoupled endothelial nitric oxide synthase in rats with experimental diabetic nephropathy
75.	2008/04	Blockade of serotonin 2A receptor improves glomerular endothelial function in rats with streptozotocin-induced diabetic nephropathy.
76.	2008/04	Pioglitazone enhances the antihypertensive and renoprotective effects of candesartan in Zucker obese rats fed a high-protein diet.
77.	2008	Abdominal pain as the initial presentation of Takayasu arteritis.
78.	2008	Co-occurrence of poststreptococcal reactive arthritis and acute glomerulonephritis.
79.	2008	Efficacy of low-dose tacrolimus added to methotrexate in patients with rheumatoid arthritis in Japan: a retrospective study.
80.	2007/10	Olmesartan ameliorates renovascular injury and oxidative stress in Zucker obese rats enhanced by dietary protein.
81.	2007/10	Pioglitazone ameliorates endothelial dysfunction in obese rats with nephropathy.
82.	2007/02	Amelioration of progressive renal injury by genetic manipulation of Klotho gene.
83.	2007/02	Isohumulones Derived from Hops Ameliorate Renal Injury via an Anti-Oxidative Effect in Dahl Salt-Sensitive Rats.
84.	2006/02	[Alport syndrome: Pathogenesis, pathophysiology, and therapy].
85.	2006/02	A nosocomial parvovirus B19 infection-induced transient aplastic crisis in a patient with chronic renal failure
86.	2006	Implication of Peritubular Capillary Loss and Altered Expression of Vascular Endothelial Growth Factor in IgA Nephropathy.
87.	2005/06	A case of Vogt-Koyanagi-Harada disease that developed relapsing polychondritis.
88.	2005/06	NAD(P)H oxidase and uncoupled nitric oxide synthase are major sources of glomerular superoxide in rats with experimental diabetic nephropathy
89.	2005	[Case of uremic platelet dysfunction]
90.	2003/12	Immunization with ACE (angiotensin converting enzyme) develops diabetic changes in the kidney and retina in diabetogenic rats.
91.	2003/06	A novel free radical scavenger, edarabone, protects against cisplatin-induced acute renal damage in vitro and in vivo.
92.	2001/11	Membranous nephropathy associated with hepatitis C virus infection.
93.	2001/06	hOGG1 polymorphism correlates with progression of IgA Nephropathy
94.	2001/04	Transdominant negative FGF receptors inhibit proliferation of cultured glomerular mesangial cells.
95.	2000	hOGG1 polymorphism correlates with progression of IgA Nephropathy (IgA GN)
96.	2000	hOGG1 polymorphism is correlated with pathogenesis of Diabetic Nephropathy (DN)
97.	2000	Oxidative stress induced peritoneal injury
98.	2000	Role of mitochondrial damage due to oxidative stress in Diabetic Nephropathy (DN)
99.	2000	Role of mitochondrial oxidative stress in the development of glomerulosclerosis
100.	1999/11	Expression of the fibroblast growth factor receptor 1-4 genes in glomeruli in anti-Thy1.1 mesangial proliferative glomerulonephritis.
101.	1999/01	Cytokines and podocyte injury: the mechanism of fibroblast growth factor 2-induced podocyte injury.
102.	1999	Podocytes mitochondria and their mit DNA mutation in mitochondrial disease
103.	1997/01	Changes in glomerular epithelial cells induced by FGF2 and FGF2 neutralizing antibody in puromycin aminonucleoside nephropathy
104.	1997	A kinetic study of glomerular epithelial cells associated with segmental glomerular sclerotic lesions with adhesion in spontaneous diabetic WBN/Kob rats.
105.	1997	Changes in glomerular epithelial cells induced by FGF2 and FGF2 neutralizing antibody in puromycin aminonucleoside nephropathy
106.	1997	Expression of tenascin in mesangial injury in experimental glomerulonephritis.
107.	1997	Kinetic study of glomerular epithelial cells associated with segmental glomerular sclerosis lesions with adhesion in spontaneovs diabetic WBN/Kob rats
108.	1996	Detection of osteopontin mRNA in epithelial cells of Bowman's capsule as revealed by in situ hybridization.
109.	1994	An Ultrastructural Study of Rat Glomerular Epithelial Cells in Culture
110.	1993	A kinetic study of the glomerular cells of developing and immature rat kidneys using an anti-bromodeoxyuridine monoclonal antibody
111.	1992	Observation of foot processes of podocytes
112.	1992	The injuries of podocytes promote irreversible glomerular sclerosis
113.	1991	Effect of N, N'-diacetylbenzidine on glomerular basement membrane formation in newborn rat kidney
114.	1991	Kinetic study of podocytes in glomerular sclerosis
115.	1990	Ultrastructural observation of the role of Bowman's epithelium in segmental glomerular sclerosis
116.	1989	A study of bone metabolism of renal osteodystrophy
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■ Presentations

1.	2024/05/23	Investigating the effects of low-level and transient DNA damage on kidney health in a novel mouse model of aging （Poster notice，General）
2.	2023/11/02	Elucidation of the Molecular Mechanism of Albuminuria Improvement by Nonsteroidal Mineralocorticoid Receptor (MR) Antagonists Focusing on Podocyte Calcium (Ca2+) Dynamics （Poster notice，General）
3.	2022/10/15	eNOS/NO signaling regulates renal interstitial fibrosis by increasing cytoplasmic beta-catenin degradation （Poster notice，General）
4.	2022/02/20	Effect of sodium-glucose cotransporter 2 inhibitor, canagliflozin, on glomerular hyperfiltration and oxidative stressin mice with type 2 diabetes. （Speech，General）
5.	2021/11/04	Elucidation of glomerular hemodynamic changes by SGLT2 Inhibitors and ARBs in a type II diabetic animal model using in vivo imaging （Poster notice，General）
6.	2021/02/28	Evaluation of glomerular hemodynamic changes by SGLT2 inhibitor and ARB in type 2 diabetic rats using in vivo imaging （Speech，General）
7.	2020/10/19	Effect of Zinc Deficiency on CKD Progression and Effect Modification by Hypoalbuminemia. （Poster notice，General）
8.	2020/10/19	eNOS/NO Signaling Attenuates Progression of Age-Related Kidney Diseases via Suppression of Inflammasome. （Poster notice，General）
9.	2020/10/02	EVALUATION OF THE MECHANISM OF GLOMERULAR ARTERIOLE CHANGES BY SGLT2 INHIBITION IN TYPE 2 DIABETIC RATS （Poster notice，General）
10.	2020/10/02	Inflammasome Activation Plays a Key Role on the Progression of Peritoneal Fibrosis in Mice （Poster notice，General）
11.	2020/10/02	THE EFFECTS OF SGLT2 INHIBITORS ON GLOMERULAR HYPERFILTRATION AND OXIDATIVE STRESS IN MICE WITH DIABETIC KIDNEY DISEASE （Poster notice，General）
12.	2020/06/07	Effects of sodium–glucose cotransporter 2 inhibitor, canagliflozin on glomerular hyperfiltration and oxidative stress in mice with type 2 diabetes （Speech，General）
13.	2020/06/07	EVALUATION OF GLOMERULAR HEMODYNAMIC CHANGES BY SGLT2 INHIBITION IN TYPE 2 DIABETIC RATS USING IN VIVO IMAGING TECHNIQUES （Speech，General）
14.	2020/06/07	KEAP1/NRF2 PATHWAY REGULATES GFR BY INCREASING THE GLOMERULAR EFFECTIVE AREA WITHOUT AFFECTING THE AFFERENT/EFFERENT ARTERIOLE RATIO （Poster notice）
15.	2020/02/15	Zinc deficiency is a risk factor for chronic kidney disease progression （Speech，General）
16.	2019/11/09	Implication of Inflammasome Activation in the Progression of Peritoneal Fibrosis in Mice （Poster notice，General）
17.	2019/11/08	Clarification of the Mechanism of Acute GFR Change by SGLT2 Inhibition with In Vivo Imaging Technique （Poster notice，General）
18.	2019/09/07	A Case of rapid decline of residual renal function after initiation of initiation of peritoneal dialysis. （Poster notice，General）
19.	2019/09/05	Inframmasome activation plays a key role in chronic inflammation and development of peri-toneal fibrosis （Poster notice，General）
20.	2019/06/13	Implication of inflammasome activation in the development of peritoneal fibrosis. （Poster notice，General）
21.	2019/06/13	Investigation of the suppressive effects of an SGLT2 inhibitor on glomerular hyperfiltration and oxidative stress in mice with diabetic kidney disease. （Poster notice，General）
22.	2019/04/12	Effect of uremic toxin-indoxcyl sulfate on intestinal defensin expression in renal failure mice. （Poster notice，General）
23.	2019/04/12	Evaluation of the diabetic glomerular hemodynamics by SGLT2 inhibitor empagliflozin using in vivo imaging. （Poster notice，General）
24.	2018/10/25	Endothelial Dysfunction Exacerbates Renal Tubular Cell Injury Through Inflammasome Activation in a Hypertensive Mouse Model （Poster notice，General）
25.	2018/10/25	Nrf2 Activator, RTAdh404, Attenuates Tubular Injury via Eliminating Mitochondrial ROS in Proteinuria Induced Renal Failure Mice （Poster notice，General）
26.	2018/10/25	Uremic Toxin Decreases Intestinal Defense Peptides and Barrier Functions in Chronic Renal Failure Mice （Poster notice，General）
27.	2018/06/23	Evaluation of Glomerular Hemodynamic Function by Empagliflozin in Diabetic Mice Using In Vivo Imaging. （Speech，General）
28.	2018/05/25	EVALUATION OF THE GLOMERULAR HEMODYNAMICS BY THE SGLT2 INHIBITOR EMPAGLIFLOZIN USING IN VIVO IMAGING （Poster notice，General）
29.	2018/05/25	NRF2 ACTIVATOR, RTADH404, ATTENUATES RENAL TUBULAR INJURY VIA MITOCHONDRIAL PROTECTION IN NEPHROTIC MODEL MICE. （Poster notice，General）
30.	2018/02/22	5-aminolevulinic acid exerts renoprotective effect via Nrf2 activation in rhabdomyolysis-induced acute kidney injury . （Poster notice，General）
31.	2018/02/22	A case of copper deficiency-induced pancytopenia with maintenance hemodialysis outpatient treated with polaprezinc . （Poster notice，General）
32.	2018/02/22	Diagnosis of a case of anti-neutrophil cytoplasmic antibody associated Glomerulonephritis during a school health examination. （Poster notice，General）
33.	2018/02/22	DPP4 inhibitor linagliptin ameliorates diabetic kidneydisease through the protection of glomerular endothelial function in mice. （Poster notice，General）
34.	2018/02/22	Effect of single pill-based combination therapy on variability of home blood pressure in hypertensive outpatients. （Poster notice，General）
35.	2018/02/22	eNOS -NO signaling attenuates renal fibrosis via suppression of catenin signaling. （Poster notice，General）
36.	2018/02/22	Evaluation of the glomerular hemodynamics alterations by SGLT2 inhibitor Empagliflozin using in vivo imaging. （Poster notice，General）
37.	2018/02/22	Membranous nephropathy diagnosed in the early stages of pregnancy :A case report. （Poster notice，General）
38.	2018/02/22	Non-purine selective xanthine oxidase inhibitor ameliorates glomerular endothelial injury in Ins2Akita diabetic mice. （Poster notice，General）
39.	2018/02/22	RTAdh404 attenuates renal inflammation and fibrosis via mitochondrial protection in ICGN mice. （Poster notice，General）
40.	2018/02/22	The association of microbiota alteration and intestinal barrier function in chronic renal failure mice. （Poster notice，General）
41.	2018/02/22	The eNOS/NO signaring attenuates glomerular injury in diabetic mice via suppression of inflammasome activation. （Poster notice，General）
42.	2018/02/10	Evaluation of the glomerular hemodynamics alterations by SGLT2 inhibitor Empagliflozin in diabetic mice using in vivo imaging. （Poster notice，General）
43.	2017/11/03	Deficient of Endothelial Function Exacerbates NLRP3-Inflammasome Activation in Podocyte of Diabetic Nephropathy （Poster notice，General）
44.	2017/11/02	Evaluation of the Reno-Protective Effects of Empagliflozin in Diabetic Nephropathy Using In Vivo Imaging （Poster notice，General）
45.	2017/09/15	DPP4 inhibitor reduces urinary albumin excretion through the protection of glomerular endothelial function （Speech，General）
46.	2017/09/15	Evaluation of the effect of empagliflozin on improving hyperfiltration in diabetic nephropathy （Speech，General）
47.	2017/06/05	ENOS/NO Signaling Attenuates Glomerular Injury in Diabetic Mice via Suppression of Inflammasome Activation. （Poster notice，General）
48.	2016/11/17	Nrf2 Dependent Inflmmasome Activation Contributes to Maintain M1 Macrophage but Not M2 Infiltration in Kidney Disease Model . （Poster notice，General）
49.	2016/11/17	The DPP-4 Inhibitor Linagliptin Reduces Albuminuria Independently of Blood Glucose Levels （Poster notice，General）
50.	2016/11/16	eNOS-NO Pathway Attenuates Chronic Inflammation via Nitric Oxide in Hypertensive Kidney Disease. （Poster notice，General）
51.	2016/09/28	Effect of Single Pill-Based Combination Therapy of Olmesartan and Azelnidipine on Variability of Home Blood Pressure in Hypertensive Outpatients. （Poster notice，General）
52.	2016/09/27	Feasibility of Fluorescence Energy Transfer System for Imaging the Renoprotective Effects of Aliskiren in Diabetic Mice. （Poster notice，General）
53.	2016/09/26	Hypertension Promotes Islet Morphological Changes with Vascular Injury on Prediabetic Status in SHR-SP Rats. （Poster notice，General）
54.	2016/09/26	Possible Implication of Xanthine Oxidase Activation on the Pathogenesis Diabetic Nephropathy. （Poster notice，General）
55.	2016/09/19	Renoprotective Effect of 5-Aminolevulinic Acid in Rhabdomyolysis-Induced Acute Kidney Injury （Speech，General）
56.	2016/09/18	Effects of Lanthanum Carbonate on Intestinal Bacterial Flora and Intestinal Barrier Function in Chronic Renal Failure Mice （Poster notice，General）
57.	2016/09/07	Clearance Gap: a new index for detection of vascular access dysfunction （Poster notice，General）
58.	2016/05/31	Feasibility of Fluorescence Energy Transfer System for Imaging the Renoprotective Effects of Aliskiren in Diabetic Mice. （Poster notice）
59.	2016/02/27	Effects of Lanthanum Carbonate on Intestinal Bacterial Flora and Intestinal Barrier Function in Chronic Renal Failure Mice （Speech，General）
60.	2015/11/07	5-Aminolevulinic Acid Attenuates Rhabdomyolysis-Induced Acute Kidney Injury in Mice . （Poster notice，General）
61.	2015/11/06	Effects of Lanthanum Carbonate on Intestinal Bacterial Flora in Chronic Renal Failure Mice. （Poster notice，General）
62.	2015/11/05	Possible Implication of Xanthine Oxidase Activation on the Pathogenesis Diabetic Nephropathy. （Poster notice，General）
63.	2015/09/28	Excess Aldosterone is a Critical Danger Signal for Inflammasome Activation in the Development of Renal Fibrosis in Mice. （Poster notice，General）
64.	2015/09/25	Possible implication of xanthine oxidase activation on the pathogenesis diabetic nephropathy. （Poster notice，General）
65.	2015/09/25	Visualization of in vivo renin activity and its application to study the pathogenetic mechanisms of diabetic nephropathy （Poster notice，General）
66.	2015/03/16	Low-Dose Colchicine Treatment Attenuates Renal Fibrosis in Mice Unilateral Ureteral Obstruction. （Poster notice，General）
67.	2015/02/28	Protective role of klotho protein on peritoneal membrane via suppression of wnt/B-catenin signaling in mice. （Speech，General）
68.	2014/11/15	Klotho Overexpression Attenuates Peritoneal Fibrosis via Suppression of Wnt/B-Catenin Signaling Pathway in Mice （Speech，General）
69.	2014/11/14	Enhancement of Wnt/B-Catenin Signaling Promotes Renal Fibrosis by Inducing Cell Cycle Arrest at the G2/M Phase in Tubular Epithelial Cells （Poster notice，General）
70.	2014/10/17	Development of a Novel In Vivo-Imaging Technique to Detect Renin-Activity in an Attempt to Elucidate Reno-Protective Effects of Calcium-Channel Blocker （Poster notice，General）
71.	2014/10/17	Molecular Mechanisms of Aldosterone-Induced Renal Interstitial Fibrosis and Ameliorative Effects of Mineralocorticoid Receptor Antagonist （Speech，General）
72.	2014/06/01	Activation of eNOS Signaling Attenuates Renal Fibrosis in Mice by The Increase of Beta Catenin Degradation. （Poster notice，General）
73.	2014/06/01	Rosuvastatin Reduces Albuminuria in Akita Diabetic mice by p21Cip1 up-regulation Through Nuclear Factor Erythroid 2-Like Factor2 Activation. （Poster notice，General）
74.	2014/06/01	The Effect of Azelnizipine on Tissue/Plasma Renin Activity in mice with Diabetic Nephropathy. （Poster notice，General）
75.	2014/05/15	Benidipine Attenuates Albuminuria Through Amelioration of Enos Uncoupling in Hypertensive Kidney Disease Model. （Poster notice，General）
76.	2014/05/15	Implication of Inflammasome Activation in The Development of Renal Interstitial Inflammation and Fibrosis Induced by Aldosterone. （Speech，General）
77.	2014/04/14	Nuclear factor erythroid 2-like factor 2 activation by rosuvastatin reduces albuminuria in Akita diabetic mice （Poster notice，General）
78.	2014/02/22	Aldosterone induces renal tubulointerstitial inflammation and fibrosis via activation of inflammasome in infltrating macrophages. （Poster notice，General）
79.	2013/11/09	Comparison of Combination Therapy with Irbesartan/Amlodipine and Irbesartan/Cilnidipine for Attenuation of Albuminuria in Rats with Streptozotocin-Induced Diabetic Nephropathy. （Poster notice，General）
80.	2013/11/09	Rosuvastatin Activates Transcription Factor Nrf2 through p21cip1 Expression and Prevents Albuminuria through Preservation of Glomerular Endothelial Integrity in AKITA Diabetic Mice. （Speech，General）
81.	2013/11/07	Implication of Inflammasome Activation via Mitochondrial Reactive Oxygen Species in the Development of Renal Interstitial Fibrosis Induced by Aldosterone. （Poster notice，General）
82.	2013/11/07	T Type Ca-Channel Blocker Exerts Anti-Albuminuic Effect through Amelioration of eNOS Uncoupling in Hypertensive Kidney Disease Model. （Poster notice，General）
83.	2013/10/26	Molecular Mechanism of Mineralocorticoid Receptor Antagonist on Suppressive Effects of Inflammasome Activation by Aldosterone. （Poster notice，General）
84.	2013/10/24	Comparison of Combination Therapy with Irbesartan/Amlodipine and Irbesartan/Cilnidipine for Attenuation of Albuminuria in Rats with Streptozotocin Induced Diabetic Nephropathy. （Poster notice，General）
85.	2013/10/24	Investigation for the Mechanisms of Anti-albuminuic Effects of T Type Ca-channel Blocker through Amelioration of eNOS Uncoupling. （Speech，General）
86.	2013/10/24	Islet Microangiopathy in Hypertensive Rats and the Protective Effects of ARB on the Islet Morphology. （Speech，General）
87.	2013/06/02	Implications of Inflammasome-Activation in Macrophage on the Development of Renal Interstitial Inflammation and Fibrosis in Mice. （Poster notice，General）
88.	2013/06/01	Development of Novel Technique to Visualize in vivo Renin Activity and Analysis of Reno-Protective Actions of Renin Inhibitor in Diabetic Nephropathy. （Poster notice，General）
89.	2013/06/01	Klotho Protein Ameliorates Peritoneal Fibrosis Though The Regulation of Wnt/B-Catenin Signaling. （Poster notice，General）
90.	2013/06/01	Rosuvastatin Maintain Glomerular Endothelial Surface layer Through Nrf2 Activation in Mouse Diabetic Nephropathy. （Poster notice，General）
91.	2013/04/28	Aldosterone induces renal interstitial inflammation and fibrosis by activation of inflammasome via mitochondrial reactive oxygen species in macrophage. （Poster notice，General）
92.	2013/04/21	Implication of inflammasome in the development of renal interstitial fibrosis induced by aldsoterone （Poster notice，General）
93.	2012/11/06	Spironolactone Suppresses the Inflammasome in Aldosterone Induced Renal Dysfunction via Blood Pressure Independent Pathway. （Poster notice，General）
94.	2012/11/03	Rosuvastatin Activates Transcription Factor Nrf2 and Protects Prevents Albuminuria through Preservation of the Glomerular Endothelial Integrity in Akita Diabetic Mice. （Poster notice，General）
95.	2012/11/02	Erythropoietin Activates NAD(P)H Oxidase via Erythropoietin Receptor and Beta Common Receptor on Vascular Endothelial Cells. （Poster notice，General）
96.	2012/11/02	Klotho Attenuates Inflammation of Adipose Tissue and Development of Insulin Resistance in High-Fat Induced Obese Mice. （Poster notice，General）
97.	2012/11/02	Overexpression of the Klotho Protein Attenuates Peritoneal Fibrosis by Suppressing Wnt-Signaling. （Poster notice，General）
98.	2012/11/02	Stimulation of Soluble Guanylate Cyclase Attenuates Epithelial-Mesenchymal Transition of the Peritoneal Membrane and Prevent the Development of Peritoneal Fibrosis. （Speech，General）
99.	2012/11/01	Development of a Novel Technique to Visualize In Vivo Renin Activity and Analysis of the Renoprotective Actions of a Renin Inhibitor. （Poster notice，General）
100.	2012/07/20	eNOS-sGC pathway suppresses renal fibrosis via interruption of the Wnt-beta-catenin pathway in UUO mice. （Poster notice，General）
101.	2012/05/26	Raloxifene Ameliorates Proteinuria-Induced Inflammasome Activation and Tubular Injury. （Poster notice，General）
102.	2012/05/25	Endothelial Dysfunction promotes the Transition from Compensatory Renal Hypertrophy to Kidney Injury after Unilateral Neophrectomy in Mice. （Poster notice）
103.	2012/05/25	Preservation of Endothelial GTP Cyclohydrolase I Activity and Improvement of Renal Nitric Oxide Availability Prevent the Development of Diabetic Nephropathy （Poster notice，General）
104.	2011/11/12	Low-Dose Erythropoietin Increases Superoxide Production in Normal Rat Aorta and Endothelial Cells （Poster notice，General）
105.	2011/11/12	Selective Estrogen Receptor Modulator Inhibits Fatty Acid-Induced Inflammasome Activation and Attenuates Proteinuria-Induced Tubular Injury in Mice （Poster notice，General）
106.	2011/11/11	Implications of Oxidative Stress Derived from Endothelial NAD(P)H Oxdase in the Development of Diabetic Nephropathy （Poster notice，General）
107.	2011/11/10	Mouse Renal Fibrosis after Unilateral Ureteral Obstruction Is Reduced by Klotho Protein Overexpression through Wnt Signaling Inhibition （Poster notice，General）
108.	2011/11/10	Preservation of Endothelial GTP Cyclohydrolase I Activity by Metformin Prevent the Development of Diabetic Nephropathy （Poster notice，General）
109.	2011/09/22	Endothelial NAD(P)H oxidase activation enhance urinary albumin excretion and progress renal dysfunction in mouse type 1 diabetic nephropathy. （Poster notice，General）
110.	2011/09/22	Role of GTP cyclohydrolase-1 as a novel therapeutic target of diabetic nephropathy. （Poster notice，General）
111.	2011/05/12	Effect of selective estrogen receptor modulator in renal proximal tubles. （Poster notice，General）
112.	2011/04/11	Selective Estrogen Receptor Modulator Ameriorate Proteinuria Induced Tubular Damage by Reducing Oxidative Mitochondrial Stress. （Poster notice，General）
113.	2011/04/10	Cyclic GMP Dependent Protein Kinase-Akt Pathway is Essential for Compensatory Renal Hypertrophy and Maintenance Renal Function After Unilateral Nephrectomy. （Poster notice，General）
114.	2011/04/10	Over-Expression of Endothelial GTP Cyclohydrolase-ⅠAmeliorates Mouse　Diabetic Glomerulopathy. （Poster notice，General）
115.	2010/11/20	Selective Estrogen Receptor Modulator Attenuates Alubumin-Induced Apoptosis in Renal Proximal Tubules through Inhibition ob Mitochondrial Stress （Poster notice，General）
116.	2010/11/19	Nitric Oxide Induces Tubular Cell Hypertrophy Via Cyclic GMP-Dependedent Protein Kinase in Rat Compensatory Renal Hypertrophy （Poster notice，General）
117.	2010/11/18	Over-Expression of GTP Cyclohydrolase-ⅠRetards Development of Albuminuria and Ameliorates Renal Injuries in Diabetes （Poster notice，General）
118.	2010/06/27	Mechanisms of acute tacrolims-induced nephrotoxicity and the renoprotective effects of telmisartan （Poster notice，General）
119.	2010/06/26	Calcium channel blokers azelnidipine but not amlodipine reduce glomerular damages in Dahl salt -sansitive rats by suppression of sympathetic nerve system （Poster notice，General）
120.	2010/06/26	Establishment of new blood purification system in renal failure rats using a small dialyzer （Poster notice，General）
121.	2010/06/26	Renal denervation reduces glomerular superoxide production and protects from gromerular injury in Dahl salt-sensitive rats （Poster notice，General）
122.	2010/06/15	Renal denervation attenuates glomerular schrelosis by suppressing NAD(P)H oxidase activity in Dahl salt-sensitive rats （Poster notice，General）
123.	2010/04/17	ARB/CCB combination therapy suppressed oxidative stress compared with ARB/HCTZ combination therapy in glomeruli and aorta of metabolic syndrome model rats （Poster notice，General）
124.	2010/04/17	Glomerular endothelial glycocalyx was decreases by reactive oxygen species in Zucker obese fatty rat （Poster notice，General）
125.	2010/04/17	Klotho overexpression attenuates renal fibrosis after unilateral obstruction by Wnt signaling inhibition （Speech，Special/Invited Lecture）
126.	2010/04/16	Renal denervation protects from glomerular injyury by suppressing NAD(P)H oxidase activity in Dahl salt-sensitive rats （Poster notice，General）
127.	2010/03/05	Deterioration of Glomerular Endothelial Glycocalyx Induced by Heparanase is Imvolved in Cardio-Renal Interaction （Poster notice，General）
128.	2009/10/31	Renal Denervation Protects Renal Function by Suppressing NAD(P)H Oxidase Activity in Dahl Salt-Sensitive Rats （Poster notice，General）
129.	2009/10/30	Azelnidipine Prevents Renal Dysfunction by Suppression of Sympathetic Nerve System in Dahl Salt-Sensitive Rats （Poster notice，General）
130.	2009/10/30	Deterioration of Glomerular Endothelial Glycocalyx Induced by Oxidative Stress is Implicated in Altered Permeability of Macromolecules in Zucker Obese Fatty Rat （Poster notice，General）
131.	2009/10/30	Increased Angiostatin Production by Nitric Oxide Reduction Induces Tubulointerstitial Damage in Rat Aging Kidney （Poster notice，General）
132.	2009/10/29	Alpha-Klotho Attenuates Renal Fibrosis after Unilateral Ureteral Obstruction through Inhibition of Wnt Signaling （Poster notice，General）
133.	2009/10/29	Comparison of the Renal and Vascular Protective Effects of Olmesartan/Azelnidipine with Olmesartan/Hydrochlorothiazide Combination Therapy in Metabolic Syndrome Model Rats （Poster notice，General）
134.	2009/10/29	Development of Novel Blood Purification System in Rats （Poster notice，General）
135.	2009/10/29	Overexpression of Klotho Protein Inhibits Uninephrectmy Induced Compensatory renal Hypertrophy by Suppressing Insulin Like Growth Factor-1 Signals （Speech，General）
136.	2009/10/29	Renoprotective Effects of Azelnidipine by Improvements of renal Microcirculation in Angiotensin ll infusion Rat. （Poster notice，General）
137.	2008/07	Relation between nitric oxide (NO) and NO-related substances in continuous ambulatory peritoneal dialysis （General）
138.	2008/02/28	Effects of high-volume or high-flow continuous renal replacement therapy and PMX-DHP for patients with septic shock （Poster notice，General）
139.	2008/02/27	Effect of High-Volume or High Flow Continuous Reanal Replacement Therapy and PMX-DHP for Patients with Septic Shock. （Poster notice，General）
140.	2008/02/27	High-Flow Isovolemic Continuous Hemodialysis Improves 28-Day Mortality in Patients with Septic Shock. （Poster notice，General）
141.	2007/11/22	Are Dietary Supplements Safe and Efficacy in Peritoneal Dyalysis? （Poster notice）
142.	2007/11/22	Direct Measurement of Nitric Oxide and Tetrahydrobiopterin Levels in Peritoneal Dialysate （Poster notice，General）
143.	2007/11/22	Measures to Maintain Appropriate Level of Serum Phosphorus （Poster notice，General）
144.	2007/10/31	Compensatory Kidney Growth after Rat Nephrectomy Requier Superoxide Via NADPH Oxidase （Poster notice，General）
145.	2007/10/31	Direct Measurement of Nitric Oxide Levels in Peritoneal Dialysate. （Poster notice，General）
146.	2007/10/31	In VivoVisualization of Glomerular Hyperfiltration and Microcircuration in STZ-Induced Diabetic Rats. （Poster notice，General）
147.	2007/04/26	Fluvastatin reverses endothelial dysfunction and increased vascular oxidative stress in rat adjuvant-induced arthritis （Speech，Panelist at Symposium/Workshop (Other)）
148.	2006/11/14	Possible Mechanism in Improvement of Progressive Renal Injuries in Klotho Over-Expressing ICGN Mice （Poster notice，General）
149.	2006/11/14	Suppression of Oxidative Stress by Combination Therapy with a Statin and an ACE Inhibitor STZ-Induced Diabetic Rat. （Poster notice，General）
150.	2006/11/14	Therapeutic Effect Pitavastatin on Renal Injury Induced by Hypertension （Poster notice，General）
151.	2006/10/20	NAD(P)H oxidase and Uncoupled Nitric Oxide Synthase are Major Sources of Superoxide in Hypertensive and Diabetic Rat Kidney （Poster notice，General）
152.	2006/10/15	Direct Method to Detect Reactive Oxygen Species (ROS) and Nitric Oxide (NO) in Kidney of Hypertensive Rats
153.	2006/10/15	Hops-derived Isohumulones Ameliorate Renal Injury through Anti-oxidative Effect in Dahl Salt-Sensitive Rats （Poster notice，General）
154.	2006/10/15	Relation of Endothelial Dysfunction in Rheumatoid Arthritis to Adiponection Level
155.	2006/10/15	Role of Reactive Oxygen Species (ROS) and Nitric Oxide (NO) in Hypertrophy in Kidney after Uninephrectomy
156.	2006/10/15	Therapeutic Effect of Pitavastatin on Renal Injury Induced by Hypertension
157.	2006/10	Sarpogrelate Hydrochloride Inhibits Reactive Oxygen Species (ROS) Production in Diabetic Nephropathy （Poster notice）
158.	2006/08/25	A Study of Tailored Nutrition Support for Peritoneal Dialysis Patients （Poster notice）
159.	2006/08/25	Direct Measurement of Effluent Nitric Oxide Levels in CAPD Patients （Poster notice）
160.	2006/08/25	The Effects of Calcium Intake and Bone Assessment Index in Continuous Ambulatory Peritoneal Dialysis(CAPD) Patients （Poster notice）
161.	2005/11/08	Implication of Senescence Associated Klotho Gene in the Pathogenesis of Progressive Renal Injuries. （Speech，General）
162.	2005/11/08	Mitochondrial Dysfunction Impairs Up-Regulation of Vascular Endothelial Growth Factor Expression in the Aging Kidney. （Poster notice，General）
163.	2005/11/08	Role of Reactive Oxygen Species (ROS) and Nitric Oxide (NO) in Hypertrophy in the Kidney after Uninephrectomy. （Poster notice，General）
164.	2004/10/27	Abnormalities in Renal Autoregulation Due to Imbalance Reactive Oxygen Species and Nitric Oxide. （Poster notice，General）
165.	2004/10/27	Losartan Improves the Imbalance between Nitric Oxide and Reactive Oxygen Species in the Diabetic Nephropathy （Poster notice，General）
166.	2004/10/27	The Role of Abnormal Iron Metabolism in the Development of Oxidative Peritoneal Injury （Poster notice，General）
167.	2003/11/12	A Long Acting Calcium Channel Blocker, Azelnidipine, Ameliorates Angiotensin II Induced Renal Damage in Rats. （Poster notice，General）
168.	2003/11/12	Calcium Channel Blocker and Angiotensin Redceptor Blocker Improve Tubulointerstitial Hypoxia and Prevent Progress of Tubular Damage in the Dahl Salt Sensitive rat Kidney （Poster notice，General）
169.	2003/11/12	Imbalance of Nitric Oxide and Reactive Oxygen species Contributes to the Progression of Renal Damage in Rat 5/6 Remmnant Model （Poster notice，General）
170.	2003/11/12	In situ Detection of Nitric Oxide in the Rat Kidney Using the Fluorescent Dye, Diaminorhodamine （Poster notice，General）
171.	2003/11/12	NAD(P)H Oxidase and Uncoupled Nitric Oxide Synthase Are Major Sources of Superoxide in the Rat Experimental Diabetic Nephropathy （Poster notice，General）
172.	2003/11/12	Progranulin (PC-Cell-Derived Growth Factor) Expression in the Kidney of Various Rat Renal Disease Models （Poster notice，General）
173.	2003/11/12	The Implications of NO and ROS Their Interaction in the Pathogenesis of Peritoneal Injury （Poster notice，General）
174.	2003/06/08	continuous hemodialysis improves the mortality of critical patients with acute renal failure in comparison with continuous hemofiltration
175.	2002/11/02	Novel Free Radical Scavenger, MCI-186,Protects Cisplatin-Induced Acute Renal Damage In Vitro and In Vivo. （Poster notice，General）
176.	2002/11/01	Impaird Angiogenesis in the Development on Interstitial Fibrosis in the Progressive Renal Diseases. （Poster notice，General）
177.	2002/11/01	the Role of Angiotensin II in yhe Genoeration of Oxidative Stress in Progressive Renal Diseases:Effects of ACEI and ARB. （Poster notice，General）
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