(Last updated : 2022-08-24 17:10:05)
  Katsuhiko Ishihara
   Department     ,
   Position   Professor with Special Assignment
■ Present specialized field
Experimental pathology, Immunology, Hematology and medical oncology, Connective tissue disease and allergy (Key Word:Immunology, early lymphopoiesis,stromal cell, BST-1/CD157, cytokine(IL-6/gp130), rheumatoid arthritis, enter-neuro-immune regulation,Parkinson's disease, depression)  Link
■ BooK
1. 2012/01   Molecular mechanisms of rheumatoid arthritis revealed by categorizing subtypes of fibroblast-like synoviocytes., Rheumatoid Arthritis – Etiology, and Consequences and Co-morbidities 
2. 2002   Analysis of human CD157 by means of murine mAbs., Leucocyte Typing VII 
3. 1997   CD157(BST-1)workshop panel report, Leucocyte typing VI 
■ Journal
1. 2021/11/19 BST1 regulates nicotinamide riboside metabolism via its glycohydrolase and base-exchange activities 
2. 2020/12/16 Distinct physical condition and social behavior phenotypes of CD157 and CD38 knockout mice during aging 
3. 2020/12/10 Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages. 
4. 2020/06/22 Nicotinamide riboside supplementation corrects deficits in oxytocin, sociability and anxiety of CD157 mutants in a mouse model of autism spectrum disorder. 
5. 2019/08 CD157 Confers Host Resistance to Mycobacterium tuberculosis via TLR2-CD157-PKCzeta-Induced Reactive Oxygen Species Production.  Link
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■ Presentation
1. 2021/05/10 Lack of bone marrow stromal cell antigen-1 (BST-1)/CD157 ameliorated colitis  induced by dextran sodium sulfate (DSS)  
2. 2020/10/24 SH3BP2 deficiency ameliorates murine systemic lupus erythematosus  
3. 2020/08/17 IL-6-PAD4 axis in the preclinical state of the synovium in gp130F759
-interaction between fibroblast-like synoviocytes and neutrophils-  
4. 2020/07/08 全身性エリテマトーデスモデルマウスにおけるアダプター蛋白SH3BP2 の自己免疫現象における役割の解明  
5. 2019/12/13 IL-6-PAD4 axis: IL-6 dependent PAD4 production in neutrophils at the earliest phase of arthritis in gp130F759.  
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■ Belonging society
1. 2009/06~ the American Association of Immunologists