Katsuhiko Ishihara
Department Kawasaki University of Medical Welfare , Position Professor with Special Assignment |
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Language | English |
Title | Bone Marrow Stromal Cell Antigen-1 Identified by RNA-Seq and ChIP-Seq Is important for Inducing Renal Ischemia-Reperfusion Injury and Fibrosis |
Conference | Kidney week 2017 |
Conference Type | International society and overseas society |
Presentation Type | Speech |
Lecture Type | General |
Publisher and common publisher | ◎Inoue Tsuyoshi, Huang Liping, Rosin Diane L.,Ishihara Katsuhiko, Wada Youichiro, Okusa Mark D. |
Date | 2017/11/04 |
Venue (city and name of the country) |
New Orleans, LA, USA |
Summary | Bst1 is a gene that is regulated by SphK2 through epigenetic change and is critical in kidney injury and fibrosis. Bst1KO mice are protected against renal IRI and develop less fibrosis. Furthermore Bst1 expression in neutrophils plays an important role in inducing renal ischemia-reperfusion injury and fibrosis. |