ヤノ　ヒロミ   Yano Hiromi   矢野　博己    所属   川崎医療福祉大学  医療技術学部 健康体育学科    職種   教授
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Relationship between macrophage differentiation and the chemotactic activity toward damaged myoblast cells
掲載誌名	正式名：Journal of Immunological Methods 略　 称：J Immunol Methods
巻・号・頁	393(1-2),pp.61-69
著者・共著者	Masataka Uchida, Eri Oyanagi, Motohiko Miyachi, Akira Yamauchi, Hiromi Yano
担当区分	最終著者,責任著者
発行年月	2013/07
概要	We investigated the effect of macrophage differentiation on the chemotactic activity to invade local damaged myoblasts using in vitro models of muscle injury. We found that: 1) the chemotactic activity of macrophages toward areas of damaged myoblasts might be induced more by live myoblasts than dead ones, 2) the chemotactic activity of macrophages is not due to velocity, but depends on the directionality toward damaged myoblast cells, and 3) macrophage differentiation strongly influence the chemotactic activity toward damaged myoblast cells through the expression of CCR2 and/or F-actin.
DOI	10.1016/j.jim.2013.04.007