小柳 えり
   Department     ,
   Position  
Article types 原著
Language English
Peer review Peer reviewed
Title Relationship between macrophage differentiation and the chemotactic activity toward damaged myoblast cells
Journal Formal name:Journal of Immunological Methods
Abbreviation:J Immunol Methods
Volume, Issue, Page 393(1-2),61-69頁
Author and coauthor Masataka Uchida, Eri Oyanagi, Motohiko Miyachi, Akira Yamauchi, Hiromi Yano
Publication date 2013/07
Summary We investigated the effect of macrophage differentiation on the chemotactic activity to invade local damaged myoblasts using in vitro models of muscle injury. We found that: 1) the chemotactic activity of macrophages toward areas of damaged myoblasts might be induced more by live myoblasts than dead ones, 2) the chemotactic activity of macrophages is not due to velocity, but depends on the directionality toward damaged myoblast cells, and 3) macrophage differentiation strongly influence the chemotactic activity toward damaged myoblast cells through the expression of CCR2 and/or F-actin.
DOI 10.1016/j.jim.2013.04.007