アラキ　シュンスケ   Syunsuke Araki   荒木　俊介    所属   川崎医療福祉大学  リハビリテーション学部 視能療法学科    職種   助教
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Foveal avascular zone and macular vessel density after correction for magnification error in unilateral amblyopia using optical coherence tomography angiography.
掲載誌名	正式名：BMC ophthalmology 略　 称：BMC Ophthalmol ISSNコード：14712415/14712415
掲載区分	国外
巻・号・頁	19(1),pp.171
著者・共著者	Syunsuke Araki, Atsushi Miki, Katsutoshi Goto, Tsutomu Yamashita, Tsuyoshi Yoneda, Kazuko Haruishi, Yoshiaki Ieki, Junichi Kiryu, Goro Maehara, Kiyoshi Yaoeda
担当区分	筆頭著者
発行年月	2019/08
概要	BACKGROUND:To investigate the area of foveal avascular zone (FAZ) and macular vessel density (VD) after correction for magnification error in unilateral amblyopia using optical coherence tomography angiography (OCTA).METHODS:Participants comprised 15 patients with unilateral amblyopia due to anisometropia with or without strabismus (mean age, 9.8 ± 3.4 years; range, 6-17 years). OCTA images were obtained by using spectral-domain OCT with angiography software. The OCTA scanning protocol used was 3 × 3-mm volume scan centered on the fovea. OCTA images were corrected for magnification errors using individual axial length (AL), and an adjusted 2.3 × 2.3-mm square was derived as a region of interest. The FAZ area and VD in both superficial capillary plexus (SCP) and deep capillary plexus (DCP) layers, foveal minimum thickness (FMT) were assessed using built-in OCTA software and ImageJ software (NIH, Bethesda, MD).RESULTS:LogMAR in the amblyopic eyes was significantly poorer than that of the fellow eye (p < 0.001). AL was significantly shorter in the amblyopic eye than in the fellow eye (p < 0.001). FAZ area of SCP in amblyopic eyes was significantly smaller than that of fellow eyes (p < 0.001). No significant differences were seen in FAZ area of DCP, VD of SCP, VD of DCP, and FMT between amblyopic and fellow eyes (p = 0.07, 0.43, 0.55, and 0.25, respectively).CONCLUSIONS:Our present study after magnification error correction found smaller FAZ area of SCP in the amblyopic eye compared with the fellow eyes, but there was no significant difference in the macular VD between the amblyopic and fellow eyes.
DOI	10.1186/s12886-019-1177-z.
PMID	31382925