Miyata Junya
   Department   Kawasaki University of Medical Welfare  ,
   Position   Instructor
Article types 原著
Language English
Peer review Peer reviewed
Title Comparison of the Dose Calculation Accuracy between the Commercial Pencil Beam Algorithm and Various Statistical Uncertainties with Monte Carlo Algorithm in New Proton Pencil Beam Scanning System
Journal Formal name:Radiation Environment and Medicine
Abbreviation:Radiat Environ Med
ISSN code:2432-163X/2423-9097
Domestic / ForeginDomestic
Volume, Issue, Page 12(1),pp.53-64
Author and coauthor Yuki Tominaga, Masataka Oita, Takashi Akagi, Junya Miyata, Shuichi Harada, Tetsunori Matsuda, Masahiro Kuroda
Publication date 2023/02
Summary We validated the calculation accuracies and times between the pencil beam algorithm (PBA) and the Monte Carlo (MC) algorithm in the new proton pencil beam scanning system. Thirty-three (homogeneous phantom) and three (heterogeneous phantom) uniform-dose plans were verified for cubic targets. These plans were calculated using the PBA and five MC statistical uncertainties of 0.3%, 0.5%, 1.0%, 1.5%, and 2.0%. We also evaluated the required dose calculation times per beam with the statistical analysis. Then, eight clinically realistic beams were validated as the end-toend test. The dose differences of 0.3% and 0.5% uncertainty MC plans were satisfied our tolerance (< ±3.0%). All five uncertainty MC plans improved at least the average/minimum gamma score from 93.8%/33.5% to 98.5%/88.9% for homogeneous (2%/2 mm) and 96.7%/83.9% to 98.8%/94.1% for heterogeneous (3%/3 mm) than PBA plans. However, the average calculation times of 0.3% and 0.5% uncertainties in MC plans were 15.5 and 5.8 times longer than in PBA plans (p < 0.001). The endto-end tests satisfied the acceptable with a statistical uncertainty of MC below 0.5%. Although the dose calculation times would be significantly increased, we suggest that the statistical uncertainty of MC below 0.5% is appropriate for clinical use with PBS plans.
DOI https://doi.org/10.51083/radiatenvironmed.12.1_53