ミヤタ　ジュンヤ   Miyata Junya   宮田　潤也    所属   川崎医療福祉大学  医療技術学部 診療放射線技術学科    職種   助教
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Comparison of the Dose Calculation Accuracy between the Commercial Pencil Beam Algorithm and Various Statistical Uncertainties with Monte Carlo Algorithm in New Proton Pencil Beam Scanning System
掲載誌名	正式名：Radiation Environment and Medicine 略　 称：Radiat Environ Med ISSNコード：2432-163X/2423-9097
掲載区分	国内
巻・号・頁	12(1),pp.53-64
著者・共著者	Yuki Tominaga, Masataka Oita, Takashi Akagi, Junya Miyata, Shuichi Harada, Tetsunori Matsuda, Masahiro Kuroda
発行年月	2023/02
概要	We validated the calculation accuracies and times between the pencil beam algorithm (PBA) and the Monte Carlo (MC) algorithm in the new proton pencil beam scanning system. Thirty-three (homogeneous phantom) and three (heterogeneous phantom) uniform-dose plans were verified for cubic targets. These plans were calculated using the PBA and five MC statistical uncertainties of 0.3%, 0.5%, 1.0%, 1.5%, and 2.0%. We also evaluated the required dose calculation times per beam with the statistical analysis. Then, eight clinically realistic beams were validated as the end-toend test. The dose differences of 0.3% and 0.5% uncertainty MC plans were satisfied our tolerance (< ±3.0%). All five uncertainty MC plans improved at least the average/minimum gamma score from 93.8%/33.5% to 98.5%/88.9% for homogeneous (2%/2 mm) and 96.7%/83.9% to 98.8%/94.1% for heterogeneous (3%/3 mm) than PBA plans. However, the average calculation times of 0.3% and 0.5% uncertainties in MC plans were 15.5 and 5.8 times longer than in PBA plans (p < 0.001). The endto-end tests satisfied the acceptable with a statistical uncertainty of MC below 0.5%. Although the dose calculation times would be significantly increased, we suggest that the statistical uncertainty of MC below 0.5% is appropriate for clinical use with PBS plans.
DOI	https://doi.org/10.51083/radiatenvironmed.12.1_53