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Shinichiro Nishimatsu
Department Kawasaki Medical School Kawasaki Medical School, Department of Natural Sciences, Position Professor |
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| Article types | 原著 |
| Language | English |
| Peer review | Peer reviewed |
| Title | Genes for bone morphogenetic proteins are differentially transcribed in early amphibian embryos. |
| Journal | Formal name：Biochemical and biophysical research communications Abbreviation：Biochem Biophys Res Commun ISSN code：0006291X/10902104 |
| Volume, Issue, Page | 186(3),pp.1487-1495 |
| Author and coauthor | Nishimatsu Shin-ichiro, Suzuki Atsushi, Shoda Akihito, Murakami Kazuo, Ueno Naoto |
| Authorship | Lead author |
| Publication date | 1992/08 |
| Summary | We have previously demonstrated that activin, a member of the TGF-beta family, has a potent mesoderm-inducing activity in Xenopus embryos. In the course of screening for activin-related genes from Xenopus, we have cloned cDNAs for Xenopus homologue of BMP-2, -4 and -7. Northern blot analysis revealed that these BMP genes are maternally encoded and differentially regulated after fertilization. Alkaline phosphatase-inducing assay using the recombinant BMP proteins has shown that at least BMP-2 and -4 have similar activity to mammalian counterparts. |
| Document No. | 1510675 |