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Shinichiro Nishimatsu
Department Kawasaki Medical School Kawasaki Medical School, Department of Natural Sciences, Position Professor |
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| Article types | 原著 |
| Language | English |
| Peer review | Peer reviewed |
| Title | Identification of chick frizzled-10 expressed in the developing limb and the central nervous system. |
| Journal | Formal name：Mechanisms of development Abbreviation：Mech Dev ISSN code：09254773/18726356 |
| Volume, Issue, Page | 91(1-2),pp.375-378 |
| Author and coauthor | Kawakami Yasuhiko, Wada Naoyuki, Nishimatsu Shin-ichiro, Komaguchi Chikako, Noji Sumihare, Nohno Tsutomu |
| Publication date | 2000/03 |
| Summary | We have identified chick frizzled (Fz)-10, encoding a Wnt receptor, and examined the expression pattern during embryogenesis. Fz-10 is expressed in the region posterior to the Hensen's node at stage 6. Fz-10 expression is detected in the dorsal domain of the neural tube and the central nervous system of the developing embryo. In the developing limb, Fz-10 expression starts at stage 18 in the posterior-dorsal region of the distal mesenchyme, and gradually expands to the anterior-distal region. Fz-10 is also expressed in the feather bud and branchial arch. Implantation of Sonic hedgehog (Shh)- expressing cells into the anterior margin of the limb bud resulted in the induction of Fz-10 expression in anterior-dorsal mesenchyme. |
| DOI | 10.1016/S0925-4773(99)00301-9 |
| Document No. | 10704868 |