玉田 勉
   Department     ,
   Position  
Article types 原著
Language English
Peer review Non peer reviewed
Title Hypointense hepatocellular nodules on hepatobiliary phase of Gd-EOB-DTPA-enhanced MRI: Can increasing the flip angle improve conspicuity of lesions?
Journal Formal name:Journal of magnetic resonance imaging : JMRI
Abbreviation:J Magn Reson Imaging
ISSN code:10531807
Volume, Issue, Page Epub ahead of print頁
Author and coauthor Tamada Tsutomu, Ito Katsuyoshi, Yamamoto Akira, Yasokawa Kazuya, Higaki Atsushi, Kanki Akihiko, Sato Tomohiro, Tanimoto Daigo, Higashi Hiroki
Publication date 2012/11
Summary We compared the conspicuity of hypointense hepatocellular nodules in patients with chronic liver disease on hepatobiliary phase (HP) of gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) acquired with low to high flip angles (FAs). In all examinations, 96 hepatocellular nodules showing hypointensity on HP were identified. These lesions included 39 hypovascular nodules and 57 hypervascular nodules. Mean CPR and LCS showed the highest value on the 30° FA, followed by 20° and 15° FAs. CPR and LCS of 15° FA were significantly lower than those of 20° and 30° FAs (P < 0.001 to P = 0.007). CPR of 30° FA for hypervascular nodules was significantly greater than that of 20° FA (P < 0.001). In conclusion, in the evaluation of hypointense hepatocellular nodules on HP of Gd-EOB-DTPA-enhanced MRI, higher FA such as 30° should be used rather than low FA such as 15°.