Tsutomu Tamada    Department   Kawasaki Medical School  Kawasaki Medical School, Department of Radiology, Division of Diagnostic Radiology,    Position   Professor
Article types	原著
Language	English
Peer review	Peer reviewed
Title	Peripheral low intensity sign in hepatic hemangioma: diagnostic pitfall in hepatobiliary phase of Gd-EOB-DTPA-enhanced MRI of the liver
Journal	Formal name：Journal of magnetic resonance imaging : JMRI Abbreviation：J Magn Reson Imaging ISSN code：10531807
Volume, Issue, Page	35(4),pp.852-852
Author and coauthor	Tamada Tsutomu, Ito Katsuyoshi, Ueki Ai, Kanki Akihiko, Higaki Atsushi, Higashi Hiroki, Yamamoto Akira
Authorship	Lead author
Publication date	2012/04
Summary	We described the presence of "peripheral low intensity sign" in hepatic hemangioma in the hepatobiliary phase (HP) of gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) and to compare the frequency of this sign between hepatic hemangiomas and hepatic metastases. Peripheral low intensity signs were demonstrated in 24 (47%) of 51 hepatic hemangiomas, while they were seen in 27 (47%) of 58 hepatic metastases. There was no significant difference in the mean visual score of peripheral low intensity sign between all hepatic hemangiomas (0.84 ± 1.03) and hepatic metastases (0.76 ± 0.92). The mean visual score of peripheral low intensity sign in typical hemangiomas (1.02 ± 1.06) was significantly higher than that in high flow hemangiomas (0.10 ± 0.32) (P = 0.008). In conclusion, peripheral low intensity sign is not specific for malignant tumors, and can be seen even in hepatic hemangiomas on HP of Gd-EOB-DTPA-enhanced MRI.