Tomoharu Tokutomi
Department Kawasaki Medical School Kawasaki Medical School, Department of Pediatrics, Position Professor with Special Assignment |
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Article types | 原著 |
Language | English |
Peer review | Peer reviewed |
Title | Characteristic profile of intestinal microflora in Kawasaki disease |
Journal | Formal name:ACTA PAEDIATRICA ISSN code:0803-5253 |
Publisher | TAYLOR & FRANCIS AS |
Volume, Issue, Page | 91(7),pp.783-788 |
Author and coauthor | S Takeshita,Kobayashi, I,Y Kawamura,T Tokutomi,Sekine, I |
Publication date | 2002 |
Summary | To investigate whether the ecology of the intestinal microflora may change in the acute phase of Kawasaki disease (KD), the distribution pattern was studied of common micro-organisms in feces from 20 patients with KD, 20 patients with acute febrile diseases (disease control) and 20 healthy children. KD patients had a significantly lower (p < 0.001) incidence of Lactobacillus (2/20, 10%) than disease control patients (16/20, 80%) and healthy children (14/20, 70%). KD patients had no significant incidences of other microbial genera, compared with both disease control and healthy children. Conclusion: The results suggest that a lack or loss of the beneficial Lactobacillus genus in the enteric microflora may occur during the acute phase of KD. |