トクトミ トモハル   Tomoharu Tokutomi
  徳富 智明
   所属   川崎医科大学  医学部 臨床医学 小児科学
   職種   特任教授
論文種別 原著
言語種別 英語
査読の有無 査読あり
表題 Standard-dose and short-term corticosteroid therapy in immunoglobulin-resistant Kawasaki disease.
掲載誌名 正式名:Clinical pediatrics
ISSNコード:0009-9228
掲載区分国外
出版社 WESTMINSTER PUBL INC
巻・号・頁 44(5),pp.423-6
著者・共著者 Seiichiro Takeshita,Youichi Kawamura,Keigo Nakatani,Hiroshi Tsujimoto,Tomoharu Tokutomi
発行年月 2005/06
概要 Six patients with Kawasaki disease (KD) were treated with prednisolone (1 to 2 mg/kg/day) for 3 days (from days 10 to 12 after the onset of the illness) after apparently unsuccessful treatment with intravenous immunoglobulin (IVIG, 2 g/kg/dose and additional 1 g/kg/dose). Five patients responded immediately to the first course of prednisolone infusion. One patient failed to respond to the first course of prednisolone therapy, but he did respond to the second 3-day course of therapy. None of the patients demonstrated a further progression of coronary artery dilatation or any adverse effects. Standard-dose and short-term corticosteroid therapy therefore appears to be a safe and effective treatment for patients with IVIG-resistant KD.
PMID 15965549