スギモト ヨシヒサ   Yoshihisa Sugimoto
  杉本 佳久
   所属   川崎医科大学  医学部 臨床医学 脊椎・関節整形外科学
   職種   講師
論文種別 原著
言語種別 英語
査読の有無 査読あり
表題 Long-Term Results of Posterior Vertebral Column Resection for Severe Thoracolumbar Kyphosis with Achondroplastic Patients: A Case Series.
掲載誌名 正式名:Medicina (Kaunas, Lithuania)
略  称:Medicina (Kaunas)
ISSNコード:16489144/1010660X
掲載区分国外
巻・号・頁 58(5),pp.605
著者・共著者 Tanaka Masato, Chan Tsang-Tung, Misawa Haruo, Uotani Koji, Arataki Shinaya, Takigawa Tomoyuki, Mazaki Tetsuro, Sugimoto Yoshihisa
発行年月 2022/04
概要 Background and Objectives: Thoracolumbar kyphosis is one of the most frequent skeletal manifestations in patients with achondroplasia. Few papers have been published on the surgical treatment of this condition, especially in skeletally mature patients. With this study, we presented a retrospective case series of long-term surgical results for achondroplastic patients with severe thoracolumbar kyphosis. This study was conducted to evaluate the outcome of surgical treatment for thoracolumbar kyphosis in patients associated with achondroplasia presenting with paraparesis. Materials and Methods: Three patients with achondroplasia who developed neurologic deficits due to severe thoracolumbar kyphosis and underwent surgical treatment were evaluated (mean age 22.3 years; mean follow-up 9.3 years). All patients were treated with posterior vertebral column resection (p-VCR) of hypoplastic apical vertebrae with a cage and segmental instrumentation. Neurologic outcomes (JOA scores), correction of kyphosis, and operative complications were assessed. Results: All patients had back pain, neurological deficits, and urinary disturbance before surgery. The average preoperative JOA score was 8.3/11 points, which was improved to 10.7/11 points at the final follow-up (mean recovery rate 83%). All patients obtained neurologic improvement after surgery. The mean preoperative kyphotic angle was 117° (range 103°-126°). The postoperative angles averaged 37° (range 14°-57°), resulting in a mean correction rate of 67%. All patients had postoperative complications such as rod breakage and/or surgical site infection. Conclusions: The long-term results of p-VCR were acceptable for treating thoracolumbar kyphosis in patients with achondroplasia. To perform this p-VCR safely, spinal navigation and neuromonitoring are inevitable when resecting non anatomical fused vertebrae and ensuring correct pedicle screw insertion. However, surgical complications such as rod breakage and surgical site infection
DOI 10.3390/medicina58050605
PMID 35630021