ワタナベ ヨシコ   Yoshiko Watanabe
  渡部 芳子
   所属   川崎医科大学  医学部 臨床医学 総合臨床医学
   職種   講師
論文種別 原著
言語種別 英語
査読の有無 査読あり
表題 Establishing clinical remission criteria for giant cell arteritis: Results of a Delphi exercise carried out by an expert panel of the Japan Research Committee of the Ministry of Health, Labour, and Welfare for Intractable Vasculitis.
掲載誌名 正式名:Modern rheumatology
略  称:Mod Rheumatol
ISSNコード:14397609/14397595
掲載区分国外
著者・共著者 Takahiko Sugihara, Hajime Yoshifuji, Haruhito A Uchida, Yasuhiro Maejima, Yoshiko Watanabe, Kazuo Tanemoto, Natsuka Umezawa, Yusuke Manabe, Jun Ishizaki, Tsuyoshi Shirai, Hiroko Nagafuchi, Hitoshi Hasegawa, Hiroaki Niiro, Tomonori Ishii, Yoshikazu Nakaoka, Masayoshi Harigai
発行年月 2023/05
概要 OBJECTIVE:To develop a proposal for giant cell arteritis (GCA) remission criteria in order to implement a treat-to-target algorithm.METHODS:A task force consisting of 10 rheumatologists, three cardiologists, one nephrologist, and one cardiac surgeon was established in the Large-vessel Vasculitis Group of the Japanese Research Committee of the Ministry of Health, Labour and Welfare for Intractable Vasculitis to conduct a Delphi survey of remission criteria for GCA. The survey was circulated among the members over four reiterations with four face-to-face meetings. Items with a mean score of ≥4 were extracted as items for defining remission criteria.RESULTS:An initial literature review yielded a total of 117 candidate items for disease activity domains and treatment/comorbidity domains of remission criteria, of which 35 were extracted as disease activity domains (systematic symptoms, signs and symptoms of cranial and large-vessel area, inflammatory markers, and imaging findings). For the treatment/comorbidity domain, ≤5 mg/day of prednisolone one year after starting GCs was extracted. The definition of achievement of remission was the disappearance of active disease in the disease activity domain, normalization of inflammatory markers, and ≤5mg/day of prednisolone.CONCLUSIONS:We developed proposals for remission criteria to guide the implementation of a treat-to-target algorithm for GCA.
DOI 10.1093/mr/road046
PMID 37225423