Shigeki Ono
   Department   Kawasaki Medical School  Kawasaki Medical School, Department of Neurosurgery 2,
   Position   Professor
Article types 症例報告
Language English
Peer review Peer reviewed
Title Parkinsonism Related to Brain Tumors: A Case Report and Review of the Literature
Journal Formal name:The Open Neurosurgery Journal
Volume, Issue, Page 2,pp.4-7
Author and coauthor Takao Yasuhara, Takashi Agari, Hirokazu Kambara, Tomotsugu Ichikawa, Kazuhiko Kurozumi, Shigeki Ono, Yasuyuki Miyoshi, Koji Tokunaga and Isao Date
Publication date 2009
Summary Parkinsonism related to brain tumor is reviewed with the presentation of our case. Neurosurgeons or neurolo- gists know that some patients with brain tumor present parkinsonism, although further enlightenment is required. The mechanisms are divided into 6 subgroups, 1. direct oppression to the basal ganglia; 2. distortion and stress to the mid- brain; 3. neuronal loss in the substantia nigra; 4. involvement of the basal ganglia; 5. damage of the fiber connection be- tween the basal ganglia and supplementary motor area; 6. old age. In the recent 11 years, 16 cases were reported. Pediatric cases, localized cases with relatively small lesion and post-irradiation cases were increasingly reported. The prognoses of brain tumor-related parkinsonism varied and independent of the pathology, location, and therapies of the tumor. All we can do is to select the appropriate therapy including surgical removal of the tumor by the correct estimation of the dam- aged region.