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Toru Fukuhara
Department Kawasaki Medical School Kawasaki Medical School, Department of Neurosurgery 2, Position Professor with Special Assignment |
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| Article types | 原著 |
| Language | English |
| Peer review | Peer reviewed |
| Title | Wegener granulomatosis manifesting as meningitis. Case report. |
| Journal | Formal name：J Neurosurg. |
| Domestic / Foregin | Foregin |
| Volume, Issue, Page | 97(5),pp.1229-1232 |
| Author and coauthor | YasuhaharaT,FukuharaToru,NakagawaM,TeraiY,YoshinoK,FujimotoS |
| Authorship | 2nd author |
| Publication date | 2002/11 |
| Summary | The authors describe a unique presentation of Wegener granulomatosis (WG) manifesting predominantly as meningitis. Magnetic resonance imaging demonstrated diffuse meningeal enhancement, including the pia mater, in a 28-year-old man with meningitis. A diagnosis of atypical WG was based on the findings of a dural biopsy sample and an elevated cytoplasmic antineutrophil cytoplasmic antibody (cANCA) titer, although the patient did not have any of the lesions common to WG. Immunosuppressive therapy was quite effective. With treatment, the meningeal enhancement resolved and the cANCA titer normalized. Meningeal granulomatosis as the sole lesion in WG has never been reported in the literature. This atypical course of WG should be noted. |