ミハラ　マサヒト   Masahito Mihara   三原　雅史    所属   川崎医科大学  医学部 臨床医学　神経内科学    職種   教授
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Neurofeedback-induced facilitation of the supplementary motor area affects postural stability.
掲載誌名	正式名：Neurophotonics 略　 称：Neurophotonics ISSNコード：2329423X/2329423X
掲載区分	国外
巻・号・頁	4(4),pp.045003
著者・共著者	Fujimoto Hiroaki, Mihara Masahito, Hattori Noriaki, Hatakenaka Megumi, Yagura Hajime, Kawano Teiji, Miyai Ichiro, Mochizuki Hideki
発行年月	2017/10
概要	Near-infrared spectroscopy-mediated neurofeedback (NIRS-NFB) is a promising therapeutic intervention for patients with neurological diseases. Studies have shown that NIRS-NFB can facilitate task-related cortical activation and induce task-specific behavioral changes. These findings indicate that the effect of neuromodulation depends on local cortical function. However, when the target cortical region has multiple functions, our understanding of the effects is less clear. This is true in the supplementary motor area (SMA), which is involved both in postural control and upper-limb movement. To address this issue, we investigated the facilitatory effect of NIRS SMA neurofeedback on cortical activity and behavior, without any specific task. Twenty healthy individuals participated in real and sham neurofeedback. Balance and hand dexterity were assessed before and after each NIRS-NFB session. We found a significant interaction between assessment periods (pre/post) and condition (real/sham) with respect to balance as assessed by the center of the pressure path length but not for hand dexterity as assessed by the 9-hole peg test. SMA activity only increased during real neurofeedback. Our findings indicate that NIRS-NFB itself has the potential to modulate focal cortical activation, and we suggest that it be considered a therapy to facilitate the SMA for patients with postural impairment.
DOI	10.1117/1.NPh.4.4.045003
PMID	29152530