Shuya Yano
   Department     Kawasaki Medical School, Department of Clinical Oncology,
   Position   Instructor
Article types 症例報告
Language English
Peer review Peer reviewed
Title Long-term Survival with a Rare Advanced Primary Gastrointestinal Malignant Melanoma Treated with Laparoscopic Surgery/Immune Checkpoint Inhibitor.
Journal Formal name:Acta medica Okayama
Abbreviation:Acta Med Okayama
ISSN code:0386300X/0386300X
Domestic / ForeginDomestic
Volume, Issue, Page 75(2),231-238頁
Author and coauthor Endo Motochika, Yano Shuya, Asano Hiroaki, Takeda Sho, Hamada Yuki, Kondo Yoshitaka, Kuroda Shinji, Shigeyasu Kunitoshi, Kikuchi Satoru, Tanaka Takehiro, Teraishi Fuminori, Nishizaki Masahiko, Kagawa Shunsuke, Fujiwara Toshiyoshi
Publication date 2021/04
Summary Targeted therapies for malignant melanoma have improved patients' prognoses. A primary gastrointestinal malignant melanoma is very rare, with no standard treatment strategy. We treated a 78-year-old Japanese female with advanced primary gastrointestinal melanoma of the descending colon and gallbladder. We administered a multidisciplinary treatment: surgical resection of the descending colon and gallbladder tumors, resection of the metastatic lymph nodes behind the pancreas head, and immune checkpoint antibody-blockade therapy (nivolumab) for ~4 years. PET/CT demonstrated no recurrent lesion for > 3 years. Multidisciplinary therapies (e.g., surgery, chemotherapy, radiotherapy, target therapy, and immune checkpoint antibody-blockade therapy) can successfully treat primary gastrointestinal malignant melanoma.
DOI 10.18926/AMO/61906
PMID 33953431