Takayuki Iwamoto
   Department   Kawasaki Medical School  Kawasaki Medical School, Department of Breast and Thyroid Surgery,
   Position   Assistant Professor
Article types 原著
Language English
Peer review Peer reviewed
Title Association between mammographic breast density and lifestyle in Japanese women.
Journal Formal name:Acta medica Okayama
Abbreviation:Acta Med Okayama
ISSN code:0386300X/0386300X
Domestic / ForeginForegin
Volume, Issue, Page 67(3),pp.145-51
Author and coauthor Setsuko Ishihara, Naruto Taira, Kensuke Kawasaki, Youichi Ishibe, Taeko Mizoo, Keiko Nishiyama, Takayuki Iwamoto, Tomohiro Nogami, Takayuki Motoki, Tadahiko Shien, Junji Matsuoka, Hiroyoshi Doihara, Yoshifumi Komoike, Shuhei Sato, Susumu Kanazawa
Publication date 2013
Summary A high mammographic breast density is considered to be a risk factor for breast cancer. However, only a small number of studies on the association between breast density and lifestyle have been performed. A cross-sectional study was performed using a survey with 29 questions on life history and lifestyle. The breast density on mammography was classified into 4 categories following the BI-RADS criteria. The subjects were 522 women with no medical history of breast cancer. The mean age was 53.3 years old. On multivariate analysis, only BMI was a significant factor determining breast density in premenopausal women (parameter estimate, -0.403; p value, 0.0005), and the density decreased as BMI rose. In postmenopausal women, BMI (parameter estimate, -0.196; p value, 0.0143) and number of deliveries (parameter estimate, -0.388; p value, 0.0186) were significant factors determining breast density;breast density decreased as BMI and number of deliveries increased. Only BMI and number of deliveries were identified as factors significantly influencing breast density. BMI was inversely correlated with breast density before and after menopause, whereas the influence of number of deliveries on breast density was significant only in postmenopausal women in their 50 and 60s.
DOI 10.18926/AMO/50407
PMID 23804137