ヤマニシ　ハルヨ   Haruyo Yamanishi   山西　治代    所属   川崎医科大学  医学部 基礎医学　解剖学    職種   講師
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Topical adenosine increases the proportion of thick hair in Caucasian men with androgenetic alopecia.
掲載誌名	正式名：The Journal of dermatology ISSNコード：13468138/03852407
掲載区分	国外
巻・号・頁	43,pp.567-70
著者・共著者	Iwabuchi T, Ideta R, Ehama R, Yamanishi H, Iino M, Nakazawa Y, Kobayashi T, Ohyama M, Kishimoto J
発行年月	2016/05
概要	Adenosine is an effective treatment for androgenetic alopecia (AGA) in Japanese men and women. Adenosine exerts its effects by significantly increasing the proportion of thick hair. In this study, we assessed the clinical outcome of adenosine treatment for 6 months in 38 Caucasian men. The change in proportion of thick hair (≥60 μm) compared with baseline in the adenosine group was significantly higher than that in the placebo group (P < 0.0001). The change in vellus hair proportion (<40 μm) was significantly lower in the adenosine group than that in the placebo group (P = 0.0154). The change in hair density compared with baseline of the adenosine group was also significantly higher compared with that of the placebo group (P = 0.0470). No adverse effects due to treatment were noted during this study by dermatological evaluation. Adenosine is effective in increasing the proportion of thick hair in Caucasian men with AGA as well as in Japanese men and women.