Shunji Endo
   Department   Kawasaki Medical School  Kawasaki Medical School, Department of Digestive Surgery,
   Position   Associate Professor
Article types 原著
Language English
Peer review Peer reviewed
Title Effect of rikkunshito, a chinese herbal medicine, on stasis in patients after pylorus-preserving gastrectomy.
Journal Formal name:World journal of surgery
Abbreviation:World J Surg
ISSN code:03642313/03642313
Domestic / ForeginForegin
Volume, Issue, Page 33(2),pp.296-302
Author and coauthor Takahashi Tsuyoshi, Endo Shunji, Nakajima Kiyokazu, Souma Yoshihito, Nishida Toshirou
Authorship 2nd author
Publication date 2009/02
Summary BACKGROUND:Distal gastrectomy (DG) and pylorus-preserving gastrectomy (PPG) have been employed for gastric cancer, with PPG having been reported to be superior to DG in regard to postoperative quality of life. Some patients with these operations still suffer from gastric stasis, however. In this study, we aimed to examine the clinical effects of rikkunshito on patients who were to undergo PPG.METHODS:A total of 11 patients who were scheduled to undergo PPG for early gastric cancer at the Osaka University Hospital were enrolled. The patients were randomly assigned to the crossover study with and without rikkunshito 7.5 g/day. Questionnaires and emptying tests using (111)In-labeled liquid scintigraphy and (99m)Tc-labeled solid scintigraphy were performed at the end of each treatment period.RESULTS:Stasis-related symptoms were significantly reduced during rikkunshito treatment (p = 0.043). The emptying test showed that rikkunshito improved emptying of solid meals (p = 0.0003) from the remnant stomach but did not accelerate gastric empting of liquid meals.CONCLUSIONS:Rikkunshito improved gastric emptying and ameliorated postoperative symptoms of patients who had undergone a PPG.
DOI 10.1007/s00268-008-9854-8
PMID 19082653