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Shunji Endo
Department Kawasaki Medical School Kawasaki Medical School, Department of Digestive Surgery, Position Associate Professor |
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| Article types | 原著 |
| Language | English |
| Peer review | Peer reviewed |
| Title | Dai-kenchu-to, a Chinese herbal medicine, improves stasis of patients with total gastrectomy and jejunal pouch interposition. |
| Journal | Formal name：American journal of surgery Abbreviation：Am J Surg ISSN code：00029610/00029610 |
| Domestic / Foregin | Foregin |
| Volume, Issue, Page | 192(1),pp.9-13 |
| Author and coauthor | Endo Shunji, Nishida Toshirou, Nishikawa Kazuhiro, Nakajima Kiyokazu, Hasegawa Jun-Ichi, Kitagawa Toru, Ito Toshinori, Matsuda Hikaru |
| Authorship | Lead author |
| Publication date | 2006/07 |
| Summary | BACKGROUND:Intestinal motility after gastric surgery frequently is disturbed and results in postoperative intestinal symptoms and poor quality of life (QOL). The purpose of this study was to examine the effects of Dai-kenchu-to on intestinal motility and postoperative QOL of patients.METHODS:Seventeen patients who underwent total gastrectomy with jejunal pouch interposition for gastric cancer in the Department of Surgery of Osaka University Medical Hospital were enrolled. The patients were assigned randomly to the cross-over study with or without 15 g/d of Dai-kenchu-to. Questionnaires and emptying tests using (111)In-labeled liquid and (99m)Tc-labeled solid test meal were performed at the end of each treatment period. A manometric study was performed in 6 patients to measure contractile activity with or without Dai-kenchu-to.RESULTS:Stasis-related symptoms were reduced significantly by Dai-kenchu-to (P = .032). In the emptying test, Dai-kenchu-to accelerated emptying of both liquid (P < .01) and solid (P = .015) meals from the pouch. The pouch showed bursts of contractions, which were increased significantly by oral intake of Dai-kenchu-to (P = .028).CONCLUSIONS:Dai-kenchu-to increased intestinal motility and decreased postoperative symptoms of patients with total gastrectomy with jejunal pouch interposition. |
| DOI | 10.1016/j.amjsurg.2006.01.022 |
| PMID | 16769267 |