教員情報 - 逸見　百江

現在の専門分野

学術雑誌

学会発表

（最終更新日：2025-05-01 18:23:15）

  イツミ　モモエ
  逸見　百江
   所属   川崎医科大学医学部一般教養　自然科学

職種助教

■ 現在の専門分野

分子生物学, 細菌学, ウイルス学, 免疫学, 腫瘍生物学, 実験動物学, 泌尿器科学　（キーワード：酸化ストレス、免疫、微生物、細胞接着、シグナル伝達）

■ 学術雑誌

1.	2025/02	原著	Experimental Murine Periodontitis Increases Salivary Gland IgA-Producing B Cells Following Oral Dysbiosis.
2.	2025/01	原著	Inflammasome regulation by the cell surface ecto-5'-nucleotidase of the oral commensal, Streptococcus oralis.
3.	2025	原著	Pathogenic effects of Streptococcus oralis intestinal colonization on bladder health in mice.
4.	2024/12	原著	Efficacy of Cetylpyridinium Chloride Mouthwash on Denture Plaque Reduction and Microbiome Alteration in a Randomized Crossover Trial.
5.	2024/03	原著	The Klebsiella mannose phosphotransferase system promotes proliferation and the production of extracellular polymeric substances from mannose, facilitating adaptation to the host environment.
6.	2023/03	原著	Oral commensal bacterial flora is responsible for peripheral differentiation of neutrophils in the oral mucosa in the steady state.
7.	2022/10	原著	Melatonin suppresses the antiviral immune response to EMCV infection through intracellular ATP deprivation caused by mitochondrial fragmentation.
8.	2022/07	原著	Novel antibody assessment method for microbial compositional alteration in the oral cavity.
9.	2022/01	原著	Coculture in vitro with endothelial cells induces cytarabine resistance of acute myeloid leukemia cells in a VEGF-A/VEGFR-2 signaling-independent manner.
10.	2021/10	原著	The downregulation of NADPH oxidase Nox4 during hypoxia in hemangioendothelioma cells: a possible role of p22phox on Nox4 protein stability.
11.	2021/02	原著	Profile of androgen receptor activators identified using high-throughput screen.
12.	2020/08	原著	High-throughput screen identifies 5-HT receptor as a modulator of AR and a therapeutic target for prostate cancer.
13.	2019/11	原著	Extracellular calcium stimulates osteogenic differentiation of human adipose-derived stem cells by enhancing bone morphogenetic protein-2 expression.
14.	2019/04	原著	Mirabegron induces relaxant effects via cAMP signaling-dependent and -independent pathways in detrusor smooth muscle.
15.	2018/02	原著	A20 restores phorbol ester-induced differentiation of THP-1 cells in the absence of nuclear factor-κB activation.
16.	2018/01	原著	Overexpression of exchange protein directly activated by cAMP-1 (EPAC1) attenuates bladder cancer cell migration.
17.	2017/06	原著	Glutathione Primes T Cell Metabolism for Inflammation.
18.	2016/07	原著	Equol inhibits prostate cancer growth through degradation of androgen receptor by S-phase kinase-associated protein 2.
19.	2016/07	原著	Potential Role for YB-1 in Castration-Resistant Prostate Cancer and Resistance to Enzalutamide Through the Androgen Receptor V7.
20.	2016/01	原著	Actions of cAMP on calcium sensitization in human detrusor smooth muscle contraction.
21.	2016	原著	Epithelial to Mesenchymal Transition in Clear Cell Renal Cell Carcinoma with Rhabdoid Features.
22.	2015/12	原著	Crosstalk between epithelial-mesenchymal transition and castration resistance mediated by Twist1/AR signaling in prostate cancer.
23.	2015/11	原著	Idh1 protects murine hepatocytes from endotoxin-induced oxidative stress by regulating the intracellular NADP(+)/NADPH ratio.
24.	2015/09	原著	SRD5A gene polymorphism in Japanese men predicts prognosis of metastatic prostate cancer with androgen-deprivation therapy.
25.	2015/04/17	原著	Idh1 protects murine hepatocytes from endotoxin-induced oxidative stress by regulating the intracellular NADP(+)/NADPH ratio
26.	2015/03	原著	Renal cancer treatment with recipient lymphocyte infusion enhanced the antitumor effect of nonmyeloablative allogeneic stem cell transplantation.
27.	2015/01	原著	Autophagy-independent functions of UVRAG are essential for peripheral naive T-cell homeostasis.
28.	2014/08	原著	PMA induces androgen receptor downregulation and cellular apoptosis in prostate cancer cells.
29.	2014/06	原著	Inhibition of RSK/YB-1 signaling enhances the anti-cancer effect of enzalutamide in prostate cancer.
30.	2014/06	原著	Targeting ribosomal S6 kinases/Y-box binding protein-1 signaling improves cellular sensitivity to taxane in prostate cancer.
31.	2014/03	原著	Largen: a molecular regulator of mammalian cell size control.
32.	2013/06	原著	Human heterochromatin protein 1 isoforms regulate androgen receptor signaling in prostate cancer.
33.	2013/06	原著	Prostaglandin receptor EP3 mediates growth inhibitory effect of aspirin through androgen receptor and contributes to castration resistance in prostate cancer cells.
34.	2013/05	原著	Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15.
35.	2013/03	原著	YB-1 suppression induces STAT3 proteolysis and sensitizes renal cancer to interferon-α.
36.	2012/09	原著	D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function.
37.	2012/05	原著	Downregulation of phosphodiesterase 4B (PDE4B) activates protein kinase A and contributes to the progression of prostate cancer.
38.	2012/05	原著	Sunitinib enhances antitumor effects against chemotherapy-resistant bladder cancer through suppression of ERK1/2 phosphorylation.
39.	2011/07	原著	Twist1 and Y-box-binding protein-1 promote malignant potential in bladder cancer cells.
40.	2010/08	原著	Sensitivity of doxorubicin-resistant cells to sorafenib: possible role for inhibition of eukaryotic initiation factor-2alpha phosphorylation.
41.	2010/02	原著	Dual specificity phosphatase16 is a negative regulator of c-Jun NH2-terminal kinase activity in T cells.
42.	2010	原著	Immunotherapy for renal cell carcinoma.
43.	2009/12	原著	Tyrosine kinase 2 plays critical roles in the pathogenic CD4 T cell responses for the development of experimental autoimmune encephalomyelitis.
44.	2009/07	原著	IL-15 is critical for the maintenance and innate functions of self-specific CD8(+) T cells.
45.	2008/11	原著	Identification of CD25+ gamma delta T cells as fetal thymus-derived naturally occurring IL-17 producers.
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■ 学会発表

1.	2024/11	Streptococcus oralis菌体表層5'-nucleotidaseの機能解析（ポスター掲示，一般）
2.	2024/11	歯周炎に伴う口腔細菌叢の乱れと唾液腺における免疫活性との関連（ポスター掲示，一般）
3.	2023/09	Klebsiellaのマンノースホスホトランスフェラーゼシステムは腸管定着関連因子である（ポスター掲示，一般）
4.	2023/09	口腔内細菌叢は口腔粘膜での好中球の末梢分化に関与している（口頭，一般）
5.	2023/02	ヒト口腔細菌叢移植マウスの急性肺障害誘導による誤嚥性肺炎マウスモデルの作製（ポスター掲示，一般）
6.	2023/02	口腔粘膜好中球の分化誘導における常在細菌叢の役割（ポスター掲示，一般）
7.	2022/07	レーザー回折法を用いたエアロゾルを発生させる歯科処置における粒子径分析（ポスター掲示，一般）
8.	2021/10	唾液を検体とした口腔健康状態評価法の開発(Development of oral health assesment using saliva) （ポスター掲示，一般）
9.	2017/09	膀胱癌由来細胞株においてEPAC1発現は細胞の移動性を抑制する（ポスター掲示，一般）
10.	2016/10	セロトニン受容体のアンタゴニストは前立腺癌の進行を抑制する（ポスター掲示，一般）
11.	2015/10	エクオールはSkp2を介したアンドロゲン受容体の分解を促進することで前立腺がんにおける細胞増殖を抑制する（ポスター掲示，一般）
12.	2015/10	前立腺癌におけるTwist1/アンドロゲン受容体シグナルによる上皮間葉転換と去勢抵抗性のクロストーク（ポスター掲示，一般）
13.	2014/09	イソフラボンは前立腺がんのアンドロゲン受容体発現を調節することで抗腫瘍効果をもたらす(Isoflavones exert anti-tumor effect through regulation of androgen receptor expression in prostate cancer) （ポスター掲示，一般）
14.	2014/09	前立腺癌におけるRSK/YB-1シグナル阻害によるエンザルタミドの抗腫瘍効果増強(Inhibition of RSK/YB-1 signaling enhances the anti-cancer effect of enzalutamide in prostate cancer) （ポスター掲示，一般）
15.	2013/10	前立腺癌におけるヒトHP-1アイソフォームによるアンドロゲン受容体シグナルの調節(Human heterochromatin protein 1 isoforms regulate androgen receptor signaling in prostate cancer) （ポスター掲示，一般）
16.	2009/11	T細胞機能調節分子とその作用メカニズム　細胞機能に焦点を当てて　IL-15は自己抗原特異的CD8陽性T細胞の維持と自然免疫機能に重要である(IL-15 is critical for the maintenance and innate functions of self-specific CD8+ T cells) （口頭，一般）
17.	2008/07	CD25陽性IL-17産生γδT細胞は胎児胸腺で機能分化を果たす（口頭，一般）
18.	2008/07	実験的自己免疫性脳脊髄炎におけるTyk2の役割（ポスター掲示，一般）
19.	2007/10	CD8T細胞の分化と機能における新規dual specificity phosphatase 16(DUSP16)の役割(Roles of a novel dual specificity phosphatase, DUSP16, in the development and functions of CD8+ T cells) （ポスター掲示，一般）
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