Faculty Information - Hiroaki Ota

（Last updated : 2023-07-05 13:45:07）

Hiroaki Ota
Department Kawasaki Medical School Kawasaki Medical School, Department of Obstetrics and Gynecology 1,

Position Professor with Special Assignment

■ Journal

1.	2023/01/28	Effect of Bone Resorption Inhibitors on Serum Cholesterol Level and Fracture Risk in Osteoporosis: Randomized Comparative Study Between Minodronic Acid and Raloxifene.
2.	2023	An online survey on coping methods for genitourinary syndrome of menopause, including vulvovaginal atrophy, among Japanese women and their satisfaction levels
3.	2022/11	TRACP-5b/BAP Score After 3 Months of Treatment With Combined SERM/E2 Therapy Can Predict Changes in Lumbar Spine Bone Mineral Density After 1 Year of Treatment in Early Postmenopausal Osteopenia.
4.	2022	Age-related changes, influencing factors and crosstalk between vaginal and gut　microbiota: a cross-sectional comparative study of pre- and　postmenopausal women
5.	2021/03/18	Risk factors for incident vertebral fractures in osteoporosis pharmacotherapy: a 2-year, prospective, observational study.
6.	2020/09	Adequate Treatment of Osteoporosis (A-TOP) Research Group. Randomized head-to-head comparison of minodronic acid and raloxifene for fracture incidence in postmenopausal Japanese women: the Japanese Osteoporosis Intervention Trial (JOINT)-04.
7.	2020	Impact of bone mineral density in reducing fracture risk in patients receiving Alendronate　plus alfacalcidol therapy.
8.	2020	Online survey of genital and urinary symptom　among Japanese women aged between 40 and 90 years.
9.	2019/05	Adequate Treatment of Osteoporosis (A-TOP) research group. Incidence of osteonecrosis of the jaw in Japanese osteoporosis patients taking minodronic acid.
10.	2019/03	Adequate Treatment of Osteoporosis (A-TOP) research group. Study design of multi-center, open-label randomized controlled, head-to-head trial comparing minodronic acid and raloxifene: Japanese Osteoporosis Intervention Trial (JOINT)-04.
11.	2019/03	Inter-relationship between diet, lifestyle habits, gut microflora, and the equol-producer phenotype: baseline findings from a placebo-controlled intervention trial.
12.	2019/03	Multiple vitamin deficiencies additively increase the risk of incident fractures in Japanese postmenopausal women.
13.	2019/01/21	Incidence of osteonecrosis of the jaw in Japanese osteoporosis patients taking minodronic acid
14.	2019	Executive summary of the Japan Osteoporosis Society Guide for the Use of Bone Turnover Markers in the Diagnosis and Treatment of Osteoporosis (2018 Edition)
15.	2019	Inter-relationship between diet, lifestyle habits, gut microflora, and the equol-producer phenotype: baseline findings from a placebo-controlled intervention trial
16.	2018/11/27	Multiple vitamin deficiencies additively increase the risk of incident fractures in Japanese postmenopausal women
17.	2018/05	Optimal vitamin D intake for preventing serum 25-hydroxyvitamin D insufficiency in young Japanese women.
18.	2017/10/06	Optimal vitamin D intake for preventing serum 25‑hydroxyvitamin D insufciency in young Japanese women
19.	2017/10	Intake of omega-3 fatty acids contributes to bone mineral density at the hip in a younger Japanese female population.
20.	2017/06/14	Intake of omega-3 fatty acids contributes to bone mineral density at the hip in a younger Japanese female population
21.	2017/04	Comparison of concurrent treatment with vitamin K2 and risedronate compared with treatment with risedronate alone in patients with osteoporosis: Japanese Osteoporosis Intervention Trial-03.
22.	2017/03	Decreased rate of hip fracture and consequent reduction in estimated medical costs in Japan.
23.	2017/02	Relationship between equol producer status and metabolic parameters in 743 Japanese women: equol producer status is associated with antiatherosclerotic conditions in women around menopause and early postmenopause.
24.	2017/01	Antiresorptive agent-related osteonecrosis of the jaw: Position Paper 2017 of the Japanese Allied Committee on Osteonecrosis of the Jaw.
25.	2017/01	Erratum to: Antiresorptive agent-related osteonecrosis of the jaw: Position Paper 2017 of the Japanese Allied Committee on Osteonecrosis of the Jaw.
26.	2017/01	Response to the Editor.
27.	2016/07	Japan Osteoporosis Society. Lack of cooperation between physicians and dentists during osteoporosis treatment may increase fractures and osteonecrosis of the jaw.
28.	2016/07	Recent nutritional trends of calcium and vitamin D in East Asia.
29.	2015/06	Impact of Osteonecrosis of the Jaw on Osteoporosis Treatment in Japan: Results of a Questionnaire-Based Survey by the Adequate Treatment of Osteoporosis (A-TOP) Research Group.
30.	2015/03	Bazedoxifene blocks AGEs-RAGE-induced superoxide generation and MCP-1 level in endothelial cells.
31.	2015/03	Incorporating bazedoxifene into the treatment paradigm for postmenopausal osteoporosis in Japan.
32.	2015/01	Bridging Analysis of the Efficacy and Safety of Bazedoxifene in Japanese and Global Populations of Postmenopausal Women with Osteoporosis.
33.	2015/01	Quality of life in Japanese women with postmenopausal osteoporosis treated with raloxifene and vitamin D: post hoc analysis of a postmarketing study.
34.	2014/03	Design of a randomized clinical trial of concurrent treatment with vitamin K2 and risedronate compared to risedronate alone in osteoporotic patients: Japanese Osteoporosis Intervention Trial-03 (JOINT-03).
35.	2014/02	Serum 25 hydroxy vitamin D level is an independent determinant for the total quality of life score in osteoporosis with high risk of fracture.
36.	2014	Sexual satisfaction of infertile couples assessed using the Golombok-Rust Inventory of Sexual Satisfaction (GRISS).
37.	2013/04	Enhanced expression of myogenic differentiation factors and skeletal muscle proteins in human amnion-derived cells via the forced expression of MYOD1.
38.	2013/04	Relationship between skipping breakfast and bone mineral density in young Japanese women.
39.	2013/03	Japanese Society for Bone and Mineral Research and Japan Osteoporosis Society Joint Review Committee for the Revision of the Diagnostic Criteria for Primary Osteoporosis. Diagnostic criteria for primary osteoporosis: year 2012 revision.
40.	2013/01	Guidelines for the use of bone metabolic markers in the diagnosis and treatment of osteoporosis (2012 edition).
41.	2012/06	An SNP in CYP39A1 is associated with severe neutropenia induced by docetaxel.
42.	2012/01	A natural S-equol supplement alleviates hot flushes and other menopausal symptoms in equol nonproducing postmenopausal Japanese women.
43.	2012/01	Japanese 2011 guidelines for prevention and treatment of osteoporosis--executive summary.
44.	2011/06	A-TOP (Adequate Treatment of Osteoporosis) research group. Effects of alendronate plus alfacalcidol in osteoporosis patients with a high risk of fracture: the Japanese Osteoporosis Intervention Trial (JOINT) - 02
45.	2011/05	Novel virtual cytological analysis for the detection of endometrial cancer cells using autoscan fluoromicroscopy.
46.	2011/03	Effects of bazedoxifene on bone mineral density, bone turnover, and safety in postmenopausal japanese women with osteoporosis.
47.	2010/06	Familial correlation of bone mineral density, birth data and lifestyle factors among adolescent daughters, mothers and grandmothers.
48.	2010/04	Bisphosphonate-Related Osteonecrosis of the Jaw : Position Paper from the Allied Task Force Committee of Japanese Society for Bone Mineral Research, Osteoporosis Society Japan, Japaese of Oral and Maxillofacial Surgeons.
49.	2010/03	Cells of extraembryonic mesodermal origin confer human dystrophin in the mdx model of Duchenne muscular dystrophy.
50.	2010/03	Effects of KRN633, an inhibitor of vascular endothelial growth factor receptor-2 tyrosine kinase, on vascular development of placenta and fetus of mid pregnancy in mice.
51.	2010/02	Impact of dietary intake, education, and physical activity on bone mineral density among North Indian women.
52.	2010/02	Riluzole use during pregnancy in a patient with amyotrophic lateral sclerosis: a case report.
53.	2010/01	Dose effects of oral estradiol on bone mineral density in Japanese women with osteoporosis.
54.	2010/01	Validation of the Japanese Osteoporosis Quality of Life Questionnaire.
55.	2009/06	Age-related Distribution of Bone and Skeletal Parameters in 1,322 Japanese Young Women.
56.	2009/06	Effect of Maternal Stress on Fetal Heart Rate Assessed by Vibroacoustic Stimulation.
57.	2009/06	The impact of lifestyle factors on serum 25-hydroxyvitamin D levels: a cross-sectional study in Japanese women aged 19 – 25 years.
58.	2009/05	Ovarian cystandenofibroma with solid nodular components masqueraded as ovarian cancer.
59.	2009/05	Variations in circulating osteoprotegerin and soluble RANKL during diurnal and menstrual cycles in young women.
60.	2009/03	Influence of maternal genetic and lifestyle factors on bone mineral density in adolescent daughters: A cohort study in 387 Japanese daughter-mother pairs.
61.	2009/01	Association between lumber bone mineral density and vascular stiffness as assessed by pulse wave velocity in postmenopausal women.
62.	2009/01	Contributions of 25-hydroxyvitamin D, co-morbidities and mass to mortality in Japanese postmenopausal women.
63.	2008/06	Possible risk factor for postmenopausal women : Postprandial hypertriglyceridemia.
64.	2008/05	Risk factors associated with preterm delivery in women with pregestational diabetes.
65.	2008/04	Pentosidine Accumulation in Human Oocytes and Their Correlation to Age-Related Apoptosis.
66.	2007/06	Effect of physical activity and nutrition on bone mineral density in young Japanese Women.
67.	2006/05	Efficacy and tolerability of once-weekly administration of 17.5 mg risedronate in Japanese patients with involutional osteoporosis : a comparison with 2.5-mg once-daily dosage regimen.
68.	2006/02	Regulation of Ankyrin Interaction with CD44 by Protein 4.1 in Hela Cells.
69.	2006/01	Immunohistochemical characteristics of mature ovarian cystic teratomas in patients with postoperative recurrence.
70.	2006/01	Peripheral arterial thrombosis induced by chemotherapy in ovarian carcinoma coexisted with endometrial carcinoma.
71.	2006/01	Prognosis in cervical insufficiency at less than 32 weeks of gestation.
72.	2006	Risk factors of preterm delivery at less than 35 weeks in patients with renal transplant.
73.	2006	Serum ionized magnesium during magnesium sulfate administration for preterm labor and preeclampsia.
74.	2006	Sister Joweph umbilical nodule coexisting with endometriosis from endometrial carcinoma
75.	2005/05	Long-term effects on bone mineral density and bone metabolism of 6month’s treatment with gonadotropin-releasing hormone analogues in Japanese women : Comparison of buserelin acetate with leupwlide acetate.
76.	2005/02	for the Committee on the Guidelines for the Use of Biochemical Markers of Bone Turnover in Osteoporosis, Japan Osteoporosis Society : Guidelines for the use of biochemical markers of bone turnover in osteoporosis (2004)
77.	2005/01	Placenta Previa Totalis Complicated with Pulmonary Embolism during Cesarean Section : A Case Report
78.	2005	Stillborn baby with partial monosomy of the short arm of chromosome 5 and partial trisomy of the short arm of chromosome 20.
79.	2004	Suppression by 17 β-estradiol of monocyte adhesion to vascular endothelial cells is mediated by estrogen receptors.
80.	2003/10	Low back pain in Japanese women: including cases caused by osteoporosis.
81.	2003/03/01	p54nrb acts as a transcriptional coactivator for activation function 1 of the human androgen receptor.
82.	2003/03	Early and Definitive Diagnosis of Toxic Shock Syndromeby Detection of Marked Expansion of T-Cell-Receptor Vβ2-Positive T Cells.
83.	2003	A case of fetal subdural hematoma at 31 weeks of gestation in a woman on warfarin therapy after cabrol's operation.
84.	2003	One-Year Spinal Bone Change in Pre- and Perimenopausal Japanese Women. A Prospective Observational Study.
85.	2002/06	A case of pregnancy with a history of paradoxical brain embolism.
86.	2002/01/01	Bone resorption versus estrogen loss following oophorectomy and menopause.
87.	2001/04	Dr. Soju Kurihara: increased awareness of cytologic diagnosis.
88.	2001/04	Vaginal symptoms in Japanese postmenopausal women: comparison with other climacteric symptoms.
89.	2001/03	Effects of counseling on climacteric symptoms in Japanese postmenopausal women.
90.	2000/03/01	Comparative effects of estrogen and raloxifene on B lymphopoiesis and bone loss induced by sex steroid deficiency in mice.
91.	2000/03	Usefulness of HMG-CoA reductase inhibitor in Japanese hyperlipidemic women within seven years of menopause.
92.	1999/04/01	Effects of 1-year ipriflavone treatment on lumbar bone mineral density and bone metabolic markers in postmenopausal women with low bone mass.
93.	1998/02	Effect of a HMG-CoA reductase inhibitor combined with hormone replacement therapy on lipid metabolism in Japanese women with hypoestrogenic lipidemia: a multicenter double-blind controlled prospective study.
94.	1998/02	Influence of bilateral oophorectomy upon lipid metabolism.
95.	1998/01	Relationship between dermato-physiological changes and hormonal status in pre-, peri-, and postmenopausal women.
96.	1997/10/01	Expression of estrogen receptor beta in rat bone.
97.	1996/03/01	Decreased bone mineral density associated with early menopause progresses for at least ten years: cross-sectional comparisons between early and normal menopausal women.
98.	1996/03/01	Effect of estriol on bone loss in postmenopausal Japanese women: a multicenter prospective open study.
99.	1996/02/01	IL-13 and IL-4 inhibit bone resorption by suppressing cyclooxygenase-2-dependent prostaglandin synthesis in osteoblasts.
100.	1994/09/01	Estrogen deficiency stimulates B lymphopoiesis in mouse bone marrow.
101.	1993/02/01	Differences in axial bone mineral density, serum levels of sex steroids, and bone metabolism between postmenopausal and age- and body size-matched premenopausal subjects
102.	1992/06/01	Influence of oophorectomy on serum levels of sex steroids and bone metabolism and assessment of bone mineral density in lumbar trabecular bone by QCT-C value.
103.	1992/03/01	Which is more osteoporosis-inducing, menopause or oophorectomy?
104.	1988/06	Endolymphatic stromal myosis coexisting with adenocarcinoma of the uterus.
105.	1984	Heat-stable alkaline phosphatase in normal uterus and deviation of isozyme profile during uterine carcinogenesis.
106.	1983/04	Newly established uterine cervical cancer cell line (SKG-III) with Regan isoenzyme, human chorionic gonadotropin beta-subunit, and pregnancy-specific beta 1-glycoprotein phenotypes.
107.	1981/06	Heat-stable alkaline phosphatase in uterine cancer, with special reference to its histochemical heat-stability and the L-phenylalanine inhibition test.
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