Present specialized field
（Last updated : 2021-10-21 16:13:16）
Present specialized field
Pharmacology, Pharmaceutical hygiene and biochemistry, Nutrition science and health science
Development of a selective fluorescence-based enzyme assay for glycerophosphodiesterase family members GDE4 and GDE7
Sphingosine 1-phosphate receptor type 2 positively regulates interleukin (IL)-4/IL-13-induced STAT6 phosphorylation
ATF4-mediated transcriptional regulation protects against β-cell loss during endoplasmic reticulum stress in a mouse model.
Involvement of acid ceramidase in the degradation of bioactive
Growth differentiation factor 15 facilitates lung fibrosis by activating macrophages and fibroblasts.
Cell-based HTS identifies a chemical chaperone for preventing ER protein aggregation and proteotoxicity.
Combined replacement effects of human modified beta-hexosaminidase B and GM2 activator protein on GM2 gangliosidoses fibroblasts.
Tailored Synthesis of 162-Residue S-Monoglycosylated GM2-Activator Protein (GM2AP) Analogues that Allows Facile Access to Protein Library.
Protease-resistant modified human beta-hexosaminidase B ameliorates symptoms in GM2 gangliosidosis model.
Development of a Chemical Methodology for the Preparation of Peptide Thioesters Applicable to Naturally Occurring Peptides Using a Sequential Quadruple Acyl Transfer System.
The total chemical synthesis of the monoglycosylated GM2 ganglioside activator using a novel cysteine surrogate.
Chemical synthesis of biologically active monoglycosylated GM2-activator protein analogue using N-sulfanylethylanilide peptide.
Lyso-GM2 ganglioside: a possible biomarker of Tay-Sachs disease and Sandhoff disease.
Therapeutic potential of intracerebroventricular replacement of modified human beta-hexosaminidase B for GM2 gangliosidosis.
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Fluorescence-based enzyme activity assay for glycerophosphodiesterase GDE4 and GDE7
The effect of p16 overexpression on gene expression of fibrosis-related factors in alveolar epithelial cells and macrophages
-acylethanolamine-hydrolyzing activity using saposin D-deficient mice
-Rho kinase pathway is necessary for full activation of STAT6 by IL-4/IL-13 in THP-1 macrophages
The role of sphingosine 1-phosphate type 2 receptor on IL-4/IL-13-stimulated STAT6 phosphorylation in phorbol12-myristate13-acetate-treated THP-1 cells
Growth differentiation factor 15 activates macrophages and fibroblasts
Role of acid ceramidase in the hydrolysis of anti-inflammatory and anorexic
Identification of a chemical chaperone for mitigating protein aggregation and proteotoxicity during endoplasmic reticulum stress
Changes in expression of fibrosis-related factors in p16 forced-expression cells
Transcription factor ATF4 maintains pancreatic β-cell identity during ER stress
The role of sphingosine 1-phosphate receptor 2 on interleukin (IL)-4/IL-13-induced STAT6 phosphorylation in phorbol 12-myristate 13-acetate-stimulated THP-1 cells
Changes in expression of fibrosis-related factors in alveolar epithelial cells and macrophages by forced expression of p16
Altered gene expression of lysophosphatidic acid receptor subtypes in ischemia/reperfusion-induced renal interstitial fibrosis in mice.
Identification of a chemical chaperone for preventing protein aggregation and proteotoxicity under endoplasmic reticulum stress
Identification of a chemical chaperone for preventing protein aggregation under ER stress
Expression of lysophosphatidic acid receptor subtypes in ischemia/reperfusion-induced renal fibrosis in mice.
Targeted deletion of ATF4 in beta-cells leads to the vulnerability and dedifferentiation during ER stress
Development of Protease-Resistant Modified Human beta-Hexosaminidase B and Evaluation of Intracerebroventricular replacement Effects on Gm2 Gangliosidosis Model Mice
SYNTHETIC STUDY OF GM2 ACTIVATOR PROTEIN USING N-SULFANYLETHYLANILIDE PEPTIDE
Replacement effects of human modified lysosomal beta-hexosaminidase B on Tay-Sachs disease and Sandhoff disease models and imaging with novel pH-activatable fluorescent probes
Replacement Effects of Human Modified Lysosomal beta-hexosaminidase B on Tay-Sachs and Sandhoff Disease Models and Imaging with Novel pH-activatable Fluorescent Probes
Development of chemical protocol for preparation of peptide/protein thioesters applicable to naturally occurring sequences
Evaluation of enzyme replacement effects and development of purification system to obtain recombinant lysosomal enzyme carrying M6P-type glycans
Vital imaging of endocytosed lysosomal enzymes with pH-activatable fluorescent probe and evaluation of enzyme replacement effects on lysosomal storage diseases
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The Japanese Pharmacological Society
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