Faculty Information - 神田　英一郎 |

（Last updated : 2021-02-23 17:46:50）

神田　英一郎
Department ,

Position

■ Present specialized field

Nephrology, Life, health and medical informatics, Mathematical informatics, Statistical science, Intelligent informatics, Applied mathematics and statistics, Life, health and medical informatics (Key Word：chronic kidney disease, nutrition, dialysis,statistics)

■ Journal

1.	2021	Postoperative recurrence of chronic subdural hematoma is more frequent in patients with blood type A
2.	2021	Postoperative recurrence of chronic subdural hematoma is more frequent in patients with blood type A.
3.	2021	The combination of malnutrition-inflammation and functional status limitations is associated with mortality in hemodialysis patients.
4.	2020/12	Optimal phase analysis of electrocardiogram-gated computed tomography angiography in patients with Stanford type A acute aortic dissection.
5.	2020/10/17	Clinical and Economic　Burden of Hyperkalemia: A Nationwide Hospital-Based Cohort Study in Japan.
6.	2020/10	Prevalences of hyperuricemia and electrolyte abnormalities in patients with chronic kidney disease in Japan: A nationwide, cross-sectional cohort study using data from the Japan Chronic Kidney Disease Database (J-CKD-DB)
7.	2020/07	Prevalence of anemia in patients with chronic kidney disease in Japan: A nationwide, cross-sectional cohort study using data from the Japan Chronic Kidney Disease Database (J-CKD-DB).
8.	2020/05	Application of explainable ensemble artificial intelligence model to categorization of hemodialysis-patient and treatment using nationwide-real-world data in Japan.
9.	2020/01	Renoprotective effects of sodium-glucose cotransporter-2 inhibitors and underlying mechanisms.
10.	2020	2018 Kidney Disease: Improving Global Outcomes (KDIGO) Hepatitis C in Chronic Kidney Disease Guideline Implementation: Asia Summit Conference Report
11.	2020	Increased plasma plasmin-alpha2-plasmin inhibitor complex levels correlate with postoperative rebleeding after endoscopic surgery for spontaneous intracerebral hemorrhage.
12.	2020	J-CKD-DB: a nationwide multicentre electronic health record-based chronic kidney disease database in Japan
13.	2020	Postdialysis blood pressure is a better predictor of mortality than predialysis blood pressure in Japanese hemodialysis patients: the Japan Dialysis Outcomes and Practice Patterns Study
14.	2020	Relationships between Smoking Status, Cardiovascular Risk Factors, and Lipoproteins in a Large Japanese Population.
15.	2020	The Normalized Protein Catabolic Rate and Mortality Risk of Patients on Hemodialysis by Frailty Status: The Japanese Dialysis Outcomes and Practice Pattern Study
16.	2019/11/28	Increased plasma plasmin-α2-plasmin inhibitor complex levels correlate with postoperative rebleeding after endoscopic surgery for spontaneous intracerebral hemorrhage.
17.	2019/10/16	Impact of Bladder Neck Involvement on Recurrence in Patients With Non-muscle-invasive Bladder Cancer: An Analysis Based on a Time-dependent Model.
18.	2019/10	Lipoprotein Subfractions and Glucose Homeostasis in Prediabetes and Diabetes in Taiwan.
19.	2019/08	Potential Impact on Lipoprotein Subfractions in Type 2 Diabetes.
20.	2019/07	Are SGLT2 inhibitors a targeted treatment for diabetic kidney disease?
21.	2019/07	Evaluation of Glomerular Hemodynamic Function by Empagliflozin in Diabetic Mice Using In Vivo Imaging.
22.	2019/05/30	Hyperkalemia in Real-World Patients Under Continuous Medical Care in Japan.
23.	2019/01	Essential points from Evidence-based Clinical Practice Guidelines for Chronic Kidney Disease 2018.
24.	2019	A new nutritional risk index for predicting mortality in hemodialysis patients: Nationwide cohort study.
25.	2019	Identifying progressive CKD from healthy population using Bayesian network and artificial intelligence: A worksite-based cohort study.
26.	2019	Relationship between Coombs-positive autoimmune hemolytic anemia and development of malignant tumors: a retrospective study
27.	2019	Use of vasopressor for dialysis-related hypotension is a risk factor for death in hemodialysis patients: Nationwide cohort study.
28.	2018/12	Guidelines for clinical evaluation of chronic kidney disease : AMED research on regulatory science of pharmaceuticals and medical devices.
29.	2018/11	Kikuchi H, Kanda E, Mori T, Sato H, Iimori S, Nomura N, Naito S, Sohara E, Okado T, Uchida S, Fushimi K, Rai T.
30.	2018/11	Patterns of adenoid and tonsil growth in Japanese children and adolescents: A longitudinal study
31.	2018/10	Dialysate Calcium Concentration below 3.0 mEq/L Is Not Associated with Improved Outcomes in the Japanese Dialysis Outcomes and Practice Patterns Study.
32.	2018/09	Observation period for changes in proteinuria and risk prediction of end-stage renal disease in general population.
33.	2018/07	SARCOPENIA AND FRAILTY IN PD: IMPACT ON MORTALITY, MALNUTRITION, AND INFLAMMATION.
34.	2018/07	The effect of small dose of topiroxostat on serum uric acid in patients receiving hemodialysis.
35.	2018/04	Importance of glomerular filtration rate change as surrogate endpoint for the future incidence of end-stage renal disease in general Japanese population: community-based cohort study.
36.	2018/04	Interventional nephrology: current status and clinical impact in Japan.
37.	2018/04	Low white blood cell count is independently associated with chronic kidney disease progression in the elderly: the CKD-ROUTE study.
38.	2018/03	Dapagliflozin improves treatment satisfaction in overweight patients with type 2 diabetes mellitus: a patient reported outcome study (PRO study).
39.	2018/03	Unexpected association between subclinical hearing loss and restorative sleep in a middle-aged and elderly Japanese population.
40.	2017/12	Association of the Clinical and Genetic Factors With Superior Vena Cava Arrhythmogenicity in Atrial Fibrillation.
41.	2017/12	Comparison of accuracy between pre-hemodialysis and post-hemodialysis levels of nutritional factors for prediction of mortality in hemodialysis patients.
42.	2017/09	Factors associated with posttraumatic growth among parents of children with cancer.
43.	2017/08	Differential changes in the adenoids and tonsils in Japanese children and teenagers: a cross-sectional study.
44.	2017/07	Effectiveness of dapagliflozin on vascular endothelial function and glycemic control in patients with early-stage type 2 diabetes mellitus: DEFENCE study.
45.	2017/06	The use of vitamin D analogs is independently associated with the favorable renal prognosis in chronic kidney disease stages 4-5: the CKD-ROUTE study.
46.	2017/05	Linagliptin improves endothelial function in patients with type 2 diabetes: A randomized study of linagliptin effectiveness on endothelial function.
47.	2017/03	Optimization of left adrenal vein sampling in primary aldosteronism: Coping with asymmetrical cortisol secretion.
48.	2017/02	Association of serum chloride level with mortality and cardiovascular events in chronic kidney disease: the CKD-ROUTE study.
49.	2017/02	Combination of low body mass index and serum albumin level is associated with chronic kidney disease progression: the chronic kidney disease-research of outcomes in treatment and epidemiology (CKD-ROUTE) study.
50.	2017/02	Mortality, Hospitalization, and Quality of Life among Patients with Hepatitis C Infection on Hemodialysis.
51.	2016/11	Association of High-Density Lipoprotein Subclasses with Chronic Kidney Disease Progression, Atherosclerosis, and Klotho.
52.	2016/08	Prevalent hyperglycemia in older obese population and age-dependent convergence of obese indices: Results of a cross-sectional study of Japanese generations over the adult life span.
53.	2016/04	Estimation of daily protein intake based on spot urine urea nitrogen concentration in chronic kidney disease patients.
54.	2016/01	Latent association between low urine pH and low body weight in an apparently healthy population.
55.	2016/01	The association of serum sodium and chloride levels with blood pressure and estimated glomerular filtration rate.
56.	2015/11	Effects of Weight Loss Speed on Kidney Function Differ Depending on Body Mass Index in Nondiabetic Healthy People: A Prospective Cohort.
57.	2015/11	Two Cases of Hemodialysis-associated Chronic Portal-systemic Shunt Encephalopathy (CPSE) with Opposite Changes in the Blood Ammonia Concentrations during Hemodialysis: A Case Report and Literature Review
58.	2015/09	A comparison of glycated albumin and glycosylated hemoglobin for the screening of diabetes mellitus in Taiwan
59.	2015/09	Use of big data in medicine.
60.	2015/08	Alcohol and Exercise Affect Declining Kidney Function in Healthy Males Regardless of Obesity: A Prospective Cohort Study.
61.	2015/06	Importance of simultaneous evaluation of multiple risk factors for hemodialysis patients' mortality and development of a novel index: dialysis outcomes and practice patterns study.
62.	2015/02	Uric acid level has a U-shaped association with loss of kidney function in healthy people: a prospective cohort study.
63.	2014/04	Decreased mobility after starting dialysis is an independent risk factor for short-term mortality after initiation of dialysis.
64.	2014/04	Subclinical hearing loss, longer sleep duration, and cardiometabolic risk factors in Japanese general population.
65.	2014/03	Causes of fever in dialysis patients and its treatment
66.	2014/03	Effects of sleepiness on survival in Japanese hemodialysis patients: J-DOPPS study.
67.	2014/02	Dietary acid intake and kidney disease progression in the elderly.
68.	2013/10	Relationship between Icodextrin use and decreased level of small low-density lipoprotein cholesterol fractioned by high-performance gel permeation chromatography.
69.	2013/10	The association of very-low-density lipoprotein with ankle-brachial index in peritoneal dialysis patients with controlled serum low-density lipoprotein cholesterol level.
70.	2013/07	Baseline characteristics and prevalence of cardiovascular disease in newly visiting or referred chronic kidney disease patients to nephrology centers in Japan: a prospective cohort study.
71.	2013/06	Anti-centromere antibody is an independent risk factor for chronic kidney disease in patients with primary biliary cirrhosis.
72.	2013/06	Dyslipidaemia in patients with chronic kidney disease and treatment
73.	2013/03	Form CMS-2728 data versus erythropoietin claims data: implications for quality of care studies.
74.	2013/01	High serum bicarbonate level within the normal range prevents the progression of chronic kidney disease in elderly chronic kidney disease patients.
75.	2012/09	Applicability of fibroblast growth factor 23 for evaluation of risk of vertebral fracture and chronic kidney disease-mineral bone disease in elderly chronic kidney disease patients.
76.	2011/05	Hemodialysis treatment center early mortality rates for incident hemodialysis patients are associated with the quality of care prior to starting but not following onset of dialysis.
77.	2008/08	Reciprocal interaction with G-actin and tropomyosin is essential for aquaporin-2 trafficking.
78.	2008/04	A familial case of mitochondrial disease resembling Alport syndrome.
79.	2007/10	A case report of thrombotic thrombocytopenic purpura and severe acute renal failure post non-myeloablative allogeneic peripheral blood stem cell transplantation treated with plasma exchange and hemodialysis.
80.	2007/07	Progression of Kidney Failure in Patients with Non-diabetic Chronic Kidney Disease under Combination Therapy in Japan
81.	2007/01	Fulminant pneumatosis intestinalis in a patient with diabetes mellitus and minimal change nephrotic syndrome.
82.	2005/06	Tuberous sclerosis, associated with renal cell carcinoma and angiomyolipoma, in a patient who developed endstage renal failure after nephrectomy.
83.	2004/12	A female patient with malarial nephropathy.
84.	2004/12	Role of cytokines in anaphylactoid reaction with marked eosinophilia in a hemodialysis patient.
85.	2003/02	Activation of Rac and tyrosine phosphorylation of cytokine receptors induced by cross-linking of integrin alpha4beta1 and cell adhesion in hematopoietic cells.
86.	2002/04	Rac is activated by erythropoietin or interleukin-3 and is involved in activation of the Erk signaling pathway.
87.	2001/08	CrkL is recruited through its SH2 domain to the erythropoietin receptor and plays a role in Lyn-mediated receptor signaling.
88.	2001/07	Rac is activated by tumor necrosis factor alpha and is involved in activation of Erk.
89.	2001/03	Rap1 is activated by erythropoietin or interleukin-3 and is involved in regulation of beta1 integrin-mediated hematopoietic cell adhesion.
90.	2001/01	IgA nephropathy with complement deficiency
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■ Presentation

1.	2020/10	Characteristics of CKD Patients with Hyperkalemia: A Report from the DISCOVER CKD Retrospective Cohort
2.	2020/10	Clinical Characteristics and eGFR and Urine Albumin-to-Creatinine Ratio Distribution According to the 2012 KDIGO CKD Classification: A Report from the DISCOVER CKD International Retrospective Cohort.
3.	2020/10	Defining the Excess Risk of Adverse Kidney Outcomes in CKD Patients with Type 2 Diabetes in the DISCOVER-CKD Cohort
4.	2020/10	Effect of Zinc Deficiency on CKD Progression and Effect Modification by Hypoalbuminemia
5.	2020/10	Effects of Improvements in Nutritional and Physical Conditions on Life Prognosis in Elderly Hemodialysis Patients in Japan
6.	2020/10	eNOS/NO Signaling Attenuates Progression of Age-Related Kidney Diseases via Suppression of Inflammasome
7.	2020/10	Machine Learning Models for Risk Prediction of Adverse Events in Hyperkalemic Patients
8.	2020/10	Machine Learning Prediction of ESKD and Death in CKD Patients: Electronic Medical Record-Based Cohort Study
9.	2020/10	Routinely Measured Cardiac Troponin I and NT-ProBNP as Predictors of Mortality in Japanese Hemodialysis Patients: The Dialysis Outcomes and Practice Patterns Study
10.	2020/10	Routinely Measured Cardiac Troponin I and NT-ProBNP as Predictors of Mortality in Japanese Hemodialysis Patients: The Dialysis Outcomes and Practice Patterns Study
11.	2020/10	The Combination of Malnutrition Inflammation and Limitations in Functional Status Is Associated with a Very High Risk of Mortality in Hemodialysis Patients: Results from the DOPPS
12.	2020/10	Treatment Pathways of CKD Patients Defined by the 2012 KDIGO CKD Classification: A Report from the DISCOVER CKD Retrospective Cohort
13.	2020/10	Treatment Pathways of Patients with CKD: A Report from the DISCOVER CKD Retrospective Cohort
14.	2020/07	Explainable artificial intelligence system for hemodialysis patients reveals disease background difference
15.	2020/06	CLINICAL CHARACTERISTICS AND EGFR AND UACR DISTRIBUTION ACCORDING TO THE 2012 KDIGO CKD CLASSIFICATION: A REPORT FROM THE US DISCOVER CKD COHORT
16.	2020/06	ROUTINELY MEASURED CARDIAC TROPONIN I AND NTPROBNP AS PREDICTORS OF MORTALITY IN JAPANESEHEMOLIALYSIS PATIENTS: THE DIALYSIS OUTCOMES AND PRACTICE PATTERNS STUDY
17.	2020/06	THE COMBINATION OF MALNUTRITION-INFLAMMATION AND LIMITATIONS IN FUNCTIONAL STATUS IS ASSOCIATED WITH A HIGH RISK OF MORTALITY IN HEMODIALYSIS PATIENTS: RESULTS FROM THE DIALYSIS OUTCOMES AND PRACTICE PATTERNS STUDY
18.	2019/11	Development and Initial Analysis of a Nationwide Multicenter Electronic Health Record Database of CKD in Japan (J-CKD-DB).
19.	2019/11	Development of an Automatic Risk-Prediction System for Hemodialysis Patients Using Artificial Intelligence: A Nationwide Dialysis Cohort Study.
20.	2019/11	Development of an Exhaustive-Risk-Prediction System Using Deep Learning and Different Patterns of Diabetic Kidney Disease Progression Based on Patient Characteristics.
21.	2019/11	Long-Term Healthcare Cost and Resource Use in Patients with Hyperkalemia.
22.	2019/11	Utilising Mobile and Web-Based Technology for Capturing Patient-Specific Information: Methods from the DISCOVER CKD Program.
23.	2019/09	Chronic Kidney Disease Patient Database in Japan.
24.	2019/09	Importance of Nutritional Status in Chronic Kidney Disease and Dialysis Patients.
25.	2018/10/27	New Nutritional Risk Index on the Basis of Protein Energy Wasting forJapanese Hemodialysis Patients
26.	2018/10/26	Beta-2 Microglobulin Levels and All-Cause Mortality: Results from the Dialysis Outcomes and Practice Patterns Study (DOPPS)
27.	2018/10/26	Predialysis Hyponatremia and Post-Dialysis Elevation in Serum Sodium Concentration During Hemodialysis as Significant Predictors of Mortality in Patients Undergoing Hemodialysis
28.	2018/06/09	CKD cohort studies in Japan
29.	2018/06/09	Endpoints in chronic kidney disease drug development
30.	2017/11	Application of AI to systematic review in Japan
31.	2017/11	Association between Body Mass Index and In-Hospital Mortality in Emergently Hospitalized Dialysis-Independent CKD Patients: A Nationwide Retrospective Cohort Study in Japan.
32.	2017/11	Evaluation of Glomerular Filtration Rate Change as an Indicator of Development of Incident CKD Using Support Vector Machine: Community-Based Prospective Cohort Study.
33.	2017/11	HDL Subclasses Alter with CKD Progression and Are Associated with ABI and Klotho Level in CKD-Stage-Specific Manner
34.	2017/11	Importance of eGFR Change as a Surrogate End Point of ESRD in a Randomized Controlled Trial
35.	2016/11	A New Risk Scoring System for Prediction of Long-Term Mortality in Patients on Maintenance Hemodialysis
36.	2016/11	Comparison of Accuracy between Pre- and Post-HD Values of Nutritonal Factors for Prediction of Mortality in Hemodialysis Patients
37.	2016/11	Evaluation of 15-Year Mortality Based on Electrocardiogram in Hemodialysis Patients Using Random Forest Machine Learning Algorithm.
38.	2016/11	Evaluation of Glomerular Filtration Rate Change as Surrogate Endpoint for End-Stage-Renal Disease
39.	2016/11	Low White Blood Cell Count Is Independently Associated with the Progression of Chronic Kidney Disease in the Elderly: The CKD-ROUTE Study
40.	2016/11	Lower Serum Magnesium Levels Are Associated with an Increased Risk of Hip Fracture in Hemodialysis Patients. A Nationwide Cohort Study
41.	2016/04	Nutritional Problems in Japanese CKD Patients
42.	2015/11	Association of Serum Chloride Level with Mortality and Cardiovascular Events in Chronic Kidney Disease. The CKD ROUTE Study.
43.	2015/11	Combination of Low Body Mass Index and Serum Albumin Level Leads to Chronic Kidney Disease Progression The Chronic Kidney Disease Research of Outcomes in Treatment and Epidemiology Study
44.	2015/05	Hepatitis C infection in hemodialysis patients is associated with inferior quality of life in the DOPPS
45.	2014/11	Changes in Protein and Salt Intakes Are Associated with the Progression of Chronic Kidney Disease
46.	2014/11	Development of a Novel Index of Nutritional Status Based on Hemodialysis Patients Mortality in Dialysis Outcomes and Practice Patterns Study DOPPS
47.	2014/11	Not Only Hyperuricemia but also Hypouricemia Is Associated with Glomerular Filtration Rate Decline in Healthy People
48.	2014/11	Vitamin D Analogs Reduce the Progression of Chronic Kidney Disease Chronic Kidney Disease Research of Outcomes in Treatment and Epidemiology Study
49.	2014/04	Asian Dialysis Cohort Study in Japan
50.	2013/11	Dietary Acid Load Is Associated with Chronic Kidney Disease Progression in Elderly Patients
51.	2013/11	Does a Low Salt Diet Affect Protein Intake in Chronic Kidney Disease Patients
52.	2013/11	Effects of Sleepiness on Survival in Japanese Hemodialysis Patients JDOPPSQ
53.	2013/11	Fluctuating Protein Intake Is an Independent Risk Factor for the Progression of Chronic Kidney Disease
54.	2013/11	Very Low Density Lipoprotein Affects Atherosclerosis of Peripheral Artery in Peritoneal Dialysis Patients
55.	2012/10	A New High-Performance Liquid Chromatography Showed That Icodextrin Dialysate Favorably Improved Lipid Profiles in Peritoneal Dialysis Patients
56.	2012/10	Estimating Daily Protein Intake by Urea Nitrogen Concentration in Spot Urine. The 46th Annual Meeting of American Society of Nephrology
57.	2012/10	Rate of Change in Fibroblast Growth Factor 23 Level Predicts the Progression of Chronic Kidney Disease in Elderly Patients
58.	2012/10	The Size and Viability of Mesothelial Cells Affect Peritoneal Membrane Functon
59.	2012/05	Cell population in peritoneal dialysis effluent reflects peritoneal membrane damage
60.	2012/05	Malnutrition and inflammation affect the viability of peritoneal mesothelial cells in peritoneal dialysis patients
61.	2011/11	Fibroblast Growth Factor 23 and Bone Metabolism in Elderly Chronic Kidney Disease Patients
62.	2011/11	Fibroblast Growth Factor 23 Is a Risk Factor for Rapid Progression of Chronic Kidney Disease in Elderly Patients
63.	2011/11	Limitations in Activities of Daily Living Independently Influences One-Year Survival of Hemodialysis Patients
64.	2011/11	Nutrition Status Prior to Starting Hemodialysis Is Strongly Associated with One Year Mortality in Hemodialysis Patients
65.	2010/11	Better Agreement between Incident Arteriovenous Fistula Status on the Centers for Medicare & Medicaid CMS-2728 Form and Medicare Claims Identifies Facilities with Better Quality of Pre-Dialysis Care
66.	2010/11	Incident Arteriovenous Fistula (AVF) and Associated Mortality: A Comparison of Medicare Claims and CMS-2728 Data
67.	2009/11	Adequacy of Care before and after Starting Hemodialysis Are Associated with Individual Patient and Treatment Center Mortality
68.	2007/11	Cell Population in Peritoneal Dialysis Effluent during Peritonitis
69.	2007/11	Cell Population in Peritoneal Dialysis Effluent during Peritonitis
70.	2007/11	Cell Population in Peritoneal Dialysis Effluent Shows Peritoneal Membrane Damage and Mesothelial Cell Transformation
71.	2007/11	Cell Population in Peritoneal Dialysis Effluent Shows Peritoneal Membrane Damage and Mesothelial Cell Transformation
72.	2007/11	Water Balance, Nutrition and Inflammation Influence on Residual Renal Function in Peritoneal Dialysis Patients
73.	2007/11	Water Balance, Nutrition and Inflammation Influence on Residual Renal function in Peritoneal Dialysis Patients
74.	2006/11	Cell population in peritoneal dialysis effluent and characteristics of peritoneal membrane
75.	2006/08	Cell population in peritoneal dialysis effluent and characteristics of peritoneal membrane
76.	2005/11	Flow cytometric analysis of mesothelial cells in peritoneal dialysis effluent
77.	2005/11	The effect of multi-mordal intervention on the progression of chronic renal failure
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■ Belonging society

1.		Association for the Advancement of Artificial Intelligence
2.		Society for Industrial and Applied Mathematics