(Last updated : 2020-05-29 19:41:56)
  坪井 一人
   Department     ,
   Position  
■ Present specialized field
Pharmacology, Medical biochemistry, Pharmaceutical hygiene and biochemistry, Pharmaceutical hygiene and biochemistry (Key Word:Lipid) 
■ BooK
1. 2020/02   Inhibition of NAPE-PLD activity by natural compounds and synthetic drugs, and its biological relevance., New tools to interrogate endocannabinoid signalling–from natural compounds to synthetic drugs. 
2. 2016/03   Assay of NAAA activity., Endocannabinoid Signaling: Methods and Protocols. 
3. 2014/09   Metabolic enzymes for endocannabinoids and endocannabinoid-like mediators., The Endocannabinoidome: The World of Endocannabinoids and Related Mediators. 
4. 2009   The N-acylethanolamine-hydrolyzing acid amidase (NAAA)., Cannabinoids in Nature and Medicine. 
5. 2002   Role of prostanoids on female reproduction revealed by receptor-deficient mice., Recent Research Developments in Endocrinology. 
■ Journal
1. 2019/12 Intracellular Ca2+-dependent formation of N-acyl-phosphatidylethanolamines by human cytosolic phospholipase A2epsilon. 
2. 2019/09 Chronic treatment with alpha-lipoic acid improves endothelium-dependent vasorelaxation of aortas in high-fat diet-fed mice. 
3. 2019/04 The role of intracellular anionic phospholipids in the production of N-acyl-phosphatidylethanolamines by cytosolic phospholipase A2epsilon. 
4. 2019/02 2-Hydroxylated fatty acids as candidates of novel drugs to promote chemosensitivity of gastric cancer. 
5. 2018/10 Endocannabinoids and related N-acylethanolamines: biological activities and metabolism. 
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■ Presentation
1. 2020/03/17 Role of acid ceramidase in the degradation of N-acylethanolamines, a group of anti-inflammatory and anorexic lipid mediators.  
2. 2020/03/17 Altered gene expression of lysophosphatidic acid receptor subtypes in ischemia/reperfusion-induced renal interstitial fibrosis in mice.  
3. 2019/07/21 Anionic phospholipids enhance the production of N-acyl-phosphatidylethanolamines by cytosolic phospholipase A2epsilon.  
4. 2019/06/19 Multiple pathways for N-acylethanolamine biosynthesis from N-acylphosphatidylethanolamine: tissue-dependent contribution of each pathway.  
5. 2019/06/19 Expression of lysophosphatidic acid receptor subtypes in ischemia/reperfusion-induced renal fibrosis in mice.  
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