(Last updated : 2022-07-07 15:06:13)
  Yasuo Okamoto
   Department     Kawasaki Medical School, Department of Pharmacology,
   Position   Professor
■ Present specialized field
Pathological biochemistry, Medical biochemistry, Pharmacology 
■ BooK
1. 2015/10   Vascular Endothelial S1P, Bioactive Lipid Mediators 
■ Journal
1. 2021/10/18 Development of a selective fluorescence-based enzyme assay for glycerophosphodiesterase family members GDE4 and GDE7. 
2. 2021/09/28 Sphingosine 1-phosphate receptor type 2 positively regulates interleukin (IL)-4/IL-13-induced STAT6 phosphorylation. 
3. 2021/09/20 ATF4-mediated transcriptional regulation protects against β-cell loss during endoplasmic reticulum stress in a mouse model. 
4. 2021/08/29 Inhibition of acid ceramidase elicits mitochondrial dysfunction and oxidative stress in pancreatic cancer cells. 
5. 2021/05/24 Involvement of acid ceramidase in the degradation of bioactive N-acylethanolamines. 
Display all(78)
■ Presentation
1. 2022/03/28 Hydrolysis of anti-inflammatory and anorexic N-acylethanolamines by acid ceramidase as revealed by using saposin D-deficient mice  
2. 2022/03/08 Development of a simple assay to measure glycerophosphodiesterase GDE4 and GDE7 activities for screening their Inhibitors  
3. 2022/03/08 Hydrolytic activity of acid ceramidase on N-acylethanolamines, anti-inflammatory and anorexic lipid mediators: an analysis using saposin D-knockout mice  
4. 2022/03/08 The crosstalk between Il-4/IL-13 and S1P/S1P2 signaling in phorbol ester-treated THP-1 MΦs  
5. 2022/03/07 Analysis of the role of macrophage senescence in lung fibrosis using macrophage-specific p16 knockout mice  
Display all(53)