Faculty Information - Satoshi Mohri

（Last updated : 2022-08-10 09:11:19）

Satoshi Mohri
Department Kawasaki Medical School Kawasaki Medical School, Department of Physiology 1,

Position Professor

■ Present specialized field

Biomedical engineering, Clinical pharmacy, Cardiology (Key Word：cardiac function, coronary circulation, medical engineering)

■ Journal

1.	2022/06/25	Protective roles of MITOL against myocardial senescence and ischemic injury partly via Drp1 regulation
2.	2022/05/20	Postnatal expression of cell cycle promoter Fam64a causes heart dysfunction by inhibiting cardiomyocyte differentiation through repression of Klf15
3.	2019/12/17	Elimination of fukutin reveals cellular and molecular pathomechanisms in muscular dystrophy-associated heart failure
4.	2019/01	Loss of Endogenous HMGB2 Promotes Cardiac Dysfunction and Pressure Overload-Induced Heart Failure in Mice.
5.	2018/08/17	Nuclear connectin novex-3 promotes proliferation of hypoxic foetal cardiomyocytes
6.	2018/05	Turtle spongious ventricles exhibit more compliant diastolic property and possess larger elastic regions of connectin in comparison to rat compact left ventricles
7.	2017/06	Fam64a is a novel cell cycle promoter of hypoxic fetal cardiomyocytes in mice.
8.	2017/02	Temperature-dependent inotropic and lusitropic indices based on half-logistic time constants for four segmental phases in isovolumic left ventricular pressure-time curve in excised, cross-circulated canine heart.
9.	2017/01	Complete primary structure of the I-band region of connectin at which mechanical property is modulated in zebrafish heart and skeletal muscle
10.	2016/11	Effects of induced Na+/Ca2+ exchanger overexpression on the spatial distribution of L-type Ca2+ channels and junctophilin-2 in pressure-overloaded hearts
11.	2016/09	ANGPTL2 Activity in Cardiac Pathologies Accelerates Heart Failure by Perturbing Cardiac Function and Energy Metabolism
12.	2016/09	Induced NCX1 overexpression attenuates pressure overload-induced pathological cardiac remodelling
13.	2016/02	Celsior preserves cardiac mechano-energetics better than University of Wisconsin solution by preventing oxidative stress.
14.	2015/12	Left ventricular mechanics and myocardial calcium dynamics in short-term and long-term hyperthyroid mice
15.	2015/08	Ankle-Brachial Index,Toe-Brachial Index,and Pulse Volume Recording In Healthy Young Adults
16.	2015/03	Cdk5rap1-Mediated 2-Methylthio Modification of Mitochondrial tRNAs Governs Protein Translation and Contributes to Myopathy in Mice and Humans
17.	2014/08	Involvement of S1P1 receptor pathway in angiogenic effects of a novel adenosine-like nucleic acid analog COA-Cl in cultured human vascular endothelial cells
18.	2014/05	TRPV2 is critical for the maintenance of cardiac structure and function in mice
19.	2012/06	Effects of propofol on left ventricular mechanoenergetics in the excised cross-circulated canine heart.
20.	2012	Live-cell visualization of the trans-cellular mode of monocyte transmigration across the vascular endothelium, and its relationship with endothelial PECAM-1.
21.	2011/09	lucose Dependency of the Metabolic Pathway of HEK 293 Cells Measured by a Flow-through Type pH/CO2 Sensor System Using ISFETs
22.	2011/06	Optical properties of in situ eye lenses measured with X-ray Talbot interferometry: a novel measure of growth processes.
23.	2011/03	Monocyte trans-endothelial migration augments subsequent transmigratory activity with increased PECAM-1 and decreased VE-cadherin at endothelial junctions
24.	2011	Cadherins in potential link between atherosclerosis and cancer
25.	2010/10	Glycocalyx degradation in retinal and choroidal capillary endothelium in rats with diabetes and hypertension.
26.	2010/09	An Experimental Model for Studying Molecular Behavior of Platelet-Endothelial Cell Adhesion Molecule-1 during Mechanical Interactions between Monocytes and Vascular Endothelial Cells
27.	2010/04	Altered Nano/Micro-Order Elasticity of Pulmonary Artery Smooth Muscle Cells of Patients with Idiopathic Pulmonary Arterial Hypertension
28.	2010/04	Altered nano/micro-order elasticity of pulmonary artery smooth muscle cells of patients with idiopathic pulmonary arterial hypertension.
29.	2010/01	A fully automated pH measurement system for 96-well microplates using a semiconductor-based pH sensor
30.	2009/12	A rapid microfluidic switching system for analysis at the single cellular level.
31.	2009/02	Impairment of leukocyte deformability in patients undergoing esophagectomy.
32.	2009/01	Mode of frequency distribution of external work efficiency of arrhythmic beats during atrial fibrillation remains normal in canine heart.
33.	2009	Protective effects of exercise preconditioning on hindlimb unloading-induced atrophy of rat soleus muscle.
34.	2008/09	Application of a flow-through type pH/CO2 sensor system based on ISFET to evaluation of the glucose dependency of the metabolic pathways in cultured cells
35.	2007/06	Impaired NO-mediated vasodilation with increased superoxide but robust EDHF function in right ventricular arterial microvessels of pulmonary hypertensive rats
36.	2007	Analysis of Effect of Radiation Exposure on Cultured Cells using Electrical Cell-substrate Impedance Sensing (ECIS) Method.
37.	2006/05	Measurements of CO< sub> 2, lactic acid and sodium bicarbonate secreted by cultured cells using a flow-through type pH/CO< sub> 2 sensor system based on ISFET
38.	2006/02	Celsior preserved cardiac mechanoenergetics better than popular solutions in canine hearts
39.	2005/06	Evaluation of micromotion of vascular endothelial cells in Electrical Cell-substrate Impedance Sensing (ECIS) method using a mathematical model
40.	2005/04	Normal distribution of ventricular pressure-volume area of arrhythmic beats under atrial fibrillation in canine heart
41.	2003	An x-ray diffraction study on contraction of rat papillary muscle with different afterloads.
42.	2001	Crossbridge dynamics examined by X-ray diffraction in cardiac muscle
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■ Presentation

1.	2018/06/19	Comparative study of tensile properties of ventricular cardiomyocytes of rat and turtle （Poster notice，General）
2.	2018/03/30	Comparison of extensibility of rat compact left ventricle and turtle spongious ventricle （Poster notice，General）
3.	2018/03/29	Elastic structures of connectin shortened in coronary circulation hearts （Poster notice，General）
4.	2018/02/21	The role of NCX1 on the maintenance of T-tubule architecture in pressure-overloaded hearts （Poster notice，General）
5.	2018/02/20	TRPV2 is Crucial for the Development of Excitation-Contraction Coupling in Neonatal Cardiomyocytes （Poster notice，General）
6.	2017/10/28	The significant role of Na+/Ca2+ exchanger 1 in heart failure （Speech，Special/Invited Lecture）
7.	2017/03/29	Effect of NCX1 on the mislocalization of junctophilin-2 in failing heart induced by pressure-overload （Poster notice，General）
8.	2016/11/17	Relationship between heart evolution and elastic structure of connectin in vertebrate （Poster notice，General）
9.	2016/04/28	Elastic structure of connectin in the hearts with coronary and non-coronary circulation （Poster notice，General）
10.	2016/04/27	Effects of inducing Na+/Ca2+ exchanger 1 expression on the microstructure in cardiomyocytes during progression of heart failure （Poster notice，General）
11.	2016/04/27	Fam64a is essential for low oxygen-induced fetal cardiomyocyte proliferation （Poster notice，General）
12.	2016/03/23	The role of NCX1 in T-tubule remodeling during progression of heart failure induced by pressure overload （Poster notice，General）
13.	2016/03/22	Elastic structures of cardiac connectin in the vertebrate hearts with coronary and sinusoidal circulation （Poster notice，General）
14.	2016/03/22	Identification of critical molecule mediating oxygen-dependent cell cycle arrest of cardiomyocytes around birth in mice （Poster notice，General）
15.	2016/01/09	Mechanical signaling via TRPV2 in cardiomyocytes （Speech，General）
16.	2015/12	TRPV2 is critical for the structural and functional maturation of cardiomyocytes （Poster notice，General）
17.	2015/05/09	Analysis of cardiac titin isoform switch around birth （Poster notice，General）
18.	2015/05/09	TRPV2 is critical for the cardiac function in adult mice （Poster notice，General）
19.	2015/03/21	Analysis of developmentally regulated cardiac titin isoform switch at birth. （Poster notice，General）
20.	2014/07/16	The critical role of Na+/Ca2+ exchanger on the maintenance of T-tubule structure （Poster notice，General）
21.	2014/07/06	Translocation of desmin from intercalated discs in TRPV2-deficient myocytes （Speech，Panelist at Symposium/Workshop (Applied)）
22.	2014/06/24	Preliminary analysis of cell cycle regulation in cardiomyocytes. （Speech，General）
23.	2014/06/11	TRPV2 is crucial for cardiac structure and function （Poster notice，Panelist at Symposium/Workshop (Other)）
24.	2014/06/11	TRPV2 maintains the structure and function of intercalated discs （Poster notice，Panelist at Symposium/Workshop (Other)）
25.	2014/03/18	Preliminary analysis of cell cycle regulation in cardiomyocytes. （Poster notice，General）
26.	2013/11/02	The role of Sodium/Calcium exchanger in maintaining T-tubule structure （Speech，General）
27.	2013/03/27	Preliminary analysis of differentiation and proliferation program of cardiomyocytes in developmental stages. （Poster notice，General）
28.	2012/10/25	Realtime observation of actindynamics in living and migrating monocytic cells with Lifeact-GFP fusion protein. （Poster notice，General）
29.	2011/04/29	Observation of leukocyte migration induced by chemoattractant injection from micropipette
30.	2011/03/28	Monocyte trans-endothelial migration facilitates subsequent transmigration with increased PECAM-1 and decreased VE-cadherin on endothelial junctions. （Poster notice，General）
31.	2011/03	Cross-Coupling between coronary vessels and cardiac muscle-physiomic perspective-. （Speech，Special/Invited Lecture）
32.	2010/09	In vitro bioimaging of monocyte trans-endothelial migration in early atherogenesis （Speech，Panelist at Symposium/Workshop (Other)）
33.	2010/08	Monocyte trans-endothelial migration induces PECAM-1 accumulation and VE-cadherin reduction at the surface of vascular endothelial cells
34.	2010/01	THE GENERATION OF A NOVEL ANIMAL MODEL OF INDUCIBLE HYPERTROPHY: OVEREXPRESSION OF NCX1 IN THE MURINE HEART USING THE DOXYCYCLINE-DEPENDENT PROMOTER （Poster notice，Panelist at Symposium/Workshop (Other)）
35.	2009/09/09	The effects of the exercise on reactive oxygen species and redox system in rats （Poster notice，General）
36.	2009/03/02	Diastolic mechanical properties of vascular and avascular hearts （Poster notice）
37.	2009/03	Increased Cardiomyocyte Elasticity in the Transverse Direction in Hypertrophied Rat Hearts Induced by Chronic β-Adrenergic Stimulation. （Speech，General）
38.	2008/03/25	Length dependent disorder of lattice spacing in rat papillary muscle （Poster notice，General）
39.	2007/03/20	Lattice spacing disorder examined by (1,0) equatorial x-ray diffraction during shortening in rat papillary muscle. （Poster notice，General）
40.	2006/03/30	Crossbridge dynamics during length clamp after preload shortening in rat papillary muscle. （Poster notice，General）
41.	2006/03/30	Transmural heterogeneity of crossbridge dynamics and lattice spacing in isolated rat hearts. （Speech，Panelist at Symposium/Workshop (Other)）
42.	2005/05/18	Transmurally difference in myocardial crossbridge dynamics and myofilament lattice spacing. （Poster notice，General）
43.	2005/03/21	Transmurally difference in crossbridge dynamics and sarcomere shortening during relaxation of isovolumic beat （Speech，General）
44.	2004/06/02	Mass transfer of myosin crossbridges during contraction in rat papillary muscle. （Poster notice，General）
45.	2004/06/02	Transmurally harmonized cardiac crossbridge formation during contraction. （Poster notice，General）
46.	2004/03/28	Harmonized transmural crossbridge formation during contraction , but discordant crossbridge decay during relaxation analyzed in beating rat heart at SPring-8 x-ray diffraction. （Speech，General）
47.	2004/03/27	Land-mine explosion in capillary-direct in vivo observation of microbubble destruction with ultrasound
48.	2003/12/05	Direct in vivo visualization of the mechanical interaction between perialveolar microcirculation and individual alveolar respirations in rats （Poster notice）
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■ Belonging society

2016/07～

Society of Evolutionary Studies, Japan