(Last updated : 2018-11-09 17:07:14)
  大槻 剛巳
   Department     ,
   Position  
■ Present specialized field
Hygiene and public health: including laboratory approach 
■ BooK
1. 2009/10   Establishment of Negatively-charged Indoor Air Conditions and their Biological Effects., Buildings and the Environment 
2. 2009/10   Immunological effects of Asbestos., Asbestos: Risks, Environment and Impact. 
3. 1998   Elevated soluble Fas Levels in patients with Silicosis., Advances in the Prevention of Occupational Respiratory Diseases (Excerpta Medica International Congress Series ICS 1153) 
4. 1998   Soluhle Fas message is dominantly expressed in cases with Silicosis., Advances in the Prevention of Occupational Respiratory Diseases (Excerpta Medica International Congress Series ICS 1153) 
■ Journal
1. 2009/12 Decrease in phosphorylation of ERK following decreased expression of NK-cell activating receptors in human NK cell line exposed to asbestos. 
2. 2009/09 Impairment in cytotoxicity and expression of NK-cell activating receptors on human NK cells following exposure to asbestos fibers. 
3. 2009/07 Cytokine alteration and speculated immunological pathophysiology in silicosis and asbestos-related diseases. 
4. 2009/07 Proposal of a new editorial polysy for EHPM and Nippon Eiseigaku Zasshi. 
5. 2009/06 Two weeks of abidance in negatively-charged air conditions causes alteration of natural killer cell function. 
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■ Presentation
1. 2010/03/07 Asbestos-exposure causes suppressed expression of NKp46 with low cytotoxicity in NK cells, related with malignant mesothelioma.  
2. 2010/03/07 Effects of asbestos on T-lymphocytes and NK cells in the development of tumor immunity.  
3. 2010/03/07 Functional analysis of human CD4+ T cells with decreased CXCR3 expression by long-term, low-dose exposure to asbestos.  
4. 2010/03/07 Suppressive effects of asbestos-ezposure on the differentiation into uhman cytotoxic T lymphocytes.  
5. 2009/11/12 胸膜プラーク陽性者NK細胞のNKp46発現量による細胞障害性の差異,石綿曝露後NKp46発現抑制機構  
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