Katsuhiko Ishihara    Department   Kawasaki University of Medical Welfare  ,    Position   Professor with Special Assignment
Language	English
Title	Bone Marrow Stromal Cell Antigen-1 Identified by RNA-Seq and ChIP-Seq Is important for Inducing Renal Ischemia-Reperfusion Injury and Fibrosis
Conference	Kidney week 2017
Conference Type	International society and overseas society
Presentation Type	Speech
Lecture Type	General
Publisher and common publisher	◎Inoue Tsuyoshi, Huang Liping, Rosin Diane L.,Ishihara Katsuhiko, Wada Youichiro, Okusa Mark D.
Date	2017/11/04
Venue (city and name of the country)	New Orleans, LA, USA
Summary	Bst1 is a gene that is regulated by SphK2 through epigenetic change and is critical in kidney injury and fibrosis. Bst1KO mice are protected against renal IRI and develop less fibrosis. Furthermore Bst1 expression in neutrophils plays an important role in inducing renal ischemia-reperfusion injury and fibrosis.