Keita Suzuki
   Department   Kawasaki University of Medical Welfare  ,
   Position   Instructor
Article types 原著
Language English
Peer review Peer reviewed
Title Dietary Calcium Intake and Hypertension: Importance of Serum Concentrations of 25-Hydroxyvitamin D.
Journal Formal name：Nutrients
Abbreviation：Nutrients
ISSN code：20726643/20726643
Domestic / ForeginForegin
Volume, Issue, Page 11(4)
Author and coauthor Haruki Nakamura, Hiromasa Tsujiguchi, Akinori Hara, Yasuhiro Kambayashi, Sakae Miyagi, Thao Thi Thu Nguyen, Keita Suzuki, Yuichi Tao, Yuriko Sakamoto, Yukari Shimizu, Norio Yamamoto, Hiroyuki Nakamura
Publication date 2019/04
Summary The relationship among dietary calcium, hypertension and vitamin D status currently remains unclear. This population-based cross-sectional study examined the association between dietary calcium intake and hypertension and the influence of serum concentrations of 25-hydroxyvitamin D [25(OH)D] in Japanese subjects. A total of 619 subjects aged from 40 years were recruited. Dietary intake was measured using a validated brief self-administered diet history questionnaire. Hypertension was defined as the use of antihypertensive medication or a blood pressure of 140/90 mmHg. Serum concentrations of 25(OH)D were used as the biomarker of vitamin D status. The prevalence of hypertension and low serum 25(OH)D levels (<20 ng/mL) were 55 and 32%, respectively. Dietary calcium intake inversely correlated with hypertension in subjects with serum 25(OH)D levels higher than 20 ng/mL (OR: 0.995; 95% CI: 0.991, 0.999) but it was not significant in those with serum 25(OH)D levels of 20 ng/mL or lower. Furthermore, dietary vitamin D intake correlated with serum concentrations of 25(OH)D after adjustments for various confounding factors. The present results demonstrate that the regular consumption of calcium may contribute to the prevention and treatment of hypertension in subjects with a non-vitamin D deficiency and also that dietary vitamin D intake may effectively prevents this deficiency.
DOI 10.3390/nu11040911
PMID 31018617