Keita Suzuki
   Department   Kawasaki University of Medical Welfare  ,
   Position   Instructor
Article types 原著
Language English
Peer review Peer reviewed
Title Relationship between handgrip strength and albuminuria in community-dwelling elderly Japanese subjects: the Shika Study.
Journal Formal name：Biomarkers
Abbreviation：Biomarkers
ISSN code：13665804/1354750X
Domestic / ForeginForegin
Volume, Issue, Page 25(7),pp.587-593
Author and coauthor Akinori Hara, Hiromasa Tsujiguchi, Keita Suzuki, Yuichi Tao, Haruki Nakamura, Tomoko Kasahara, Thao Thi Thu Nguyen, Sakae Miyagi, Yukari Shimizu, Takayuki Kannon, Atsushi Tajima, Takashi Wada, Toshinari Takamura, Hiroyuki Nakamura
Publication date 2020/11
Summary PURPOSE:This study aimed to investigate the association between handgrip strength (HGS) and albuminuria in the general population of Japan as per sex and age.METHODS:This population-based, cross-sectional study enrolled 916 Japanese participants aged ≥40 years. Albuminuria was measured and expressed as the urinary albumin-to-creatinine ratio (UACR). Biochemical, nutritional, and anthropometric profiles as well as HGS were measured using standardised protocols.RESULTS:Four hundred and thirty-two (47%) of the study participants were men, and 484 were women, with respective mean ages of 62 ± 11 years and 63 ± 11 years. HGS, older age, high body mass index, presence of hypertension or diabetes, and a decreased estimated glomerular filtration rate were correlated with the log-transformed UACR in subjects of both sexes. Multivariate linear regression analysis showed that HGS was independently associated with the log UACR in both, men [beta coefficient -0.43; 95% confidence interval (CI) -0.73, -0.13] and women (beta coefficient -0.50; 95% CI -0.90, -0.10) aged ≥65 years; however, a similar association was not observed in younger participants.CONCLUSION:Low HGS was associated with albuminuria in older men and women in Japan.
DOI 10.1080/1354750X.2020.1819418
PMID 32893687