Keita Suzuki    Department   Kawasaki University of Medical Welfare  ,    Position   Instructor
Article types	原著
Language	English
Peer review	Peer reviewed
Title	Association between animal protein intake, oral frailty and calf circumference in middle-aged and older adults: a cross-sectional analysis from the Shika study.
Journal	Formal name：BMJ open Abbreviation：BMJ Open ISSN code：20446055/20446055
Domestic / Foregin	Foregin
Volume, Issue, Page	14(2),pp.e078129
Author and coauthor	Fumihiko Suzuki, Shigefumi Okamoto, Shingo Nakai, Sakae Miyagi, Hiromasa Tsujiguchi, Akinori Hara, Thao Thi Thu Nguyen, Yukari Shimizu, Koichiro Hayashi, Keita Suzuki, Tomoko Kasahara, Masaharu Nakamura, Chie Takazawa, Aya Ogawa, Aki Shibata, Takayuki Kannon, Atsushi Tajima, Hirohito Tsuboi, Noriyoshi Ogino, Tadashi Konoshita, Toshinari Takamura, Kuniko Sato, Hiroyuki Nakamura
Publication date	2024/02
Summary	OBJECTIVE:To investigate the relationship between oral frailty (OF), nutrient intake and calf circumference (CC) in middle-aged and older adults.DESIGN:Cross-sectional study.SETTING:Residents of four model districts of Shika town, Ishikawa Prefecture, Japan, using data from November 2017 to February 2018.PARTICIPANTS:One hundred and ninety-four residents aged ≥50 years in four model districts of Shika town. The OF total score ≥3 was defined as OF. Participants were divided into OF and non-OF groups and divided into the low-CC/kg and the high-CC/kg groups.OUTCOME MEASURES:The primary outcome is to use a two-way analysis of covariance to analyse the interaction between the two CC/kg groups and the two OF groups on nutrition intake. The secondary outcome is to use multiple regression analysis to investigate the nutrients significantly related to CC/kg when stratified by OF, with age, sex, body mass index, drinking status, smoking status and regular exercise as input covariates.RESULTS:A two-way analysis of covariance revealed a significant interaction between the two CC/kg groups and the two OF groups on animal protein intake (p=0.039). Multiple comparisons using the Bonferroni analysis revealed a significantly lower animal protein intake in the OF group than in the non-OF group with a low CC/kg (p=0.033) but not in the group with a high CC/kg. The multiple regression analysis stratified by OF revealed a positive correlation between animal protein intake and CC/kg (p=0.002).CONCLUSIONS:The present results revealed a significantly lower animal protein intake in the OF group than in the non-OF group in the low-CC/kg group, but no such difference was observed in the high-CC/kg group. Further longitudinal studies are needed to elucidate this relationship.
DOI	10.1136/bmjopen-2023-078129
PMID	38365294