Kaoru Tohyama
   Department   Kawasaki University of Medical Welfare  ,
   Position   Professor with Special Assignment
Article types 原著
Language English
Peer review Peer reviewed
Title Interference by Pralidoxime (PAM) Salts in Clinical Laboratory Tests
Journal Formal name:Clinica Chimica Acta
Abbreviation:Clin Chim Acta
ISSN code:0009-8981
Volume, Issue, Page 416,pp.72-79
Author and coauthor Sumika Nagase, Katsunori Kohguchi, Kaoru Tohyama, Mikio Watanabe, Yoshonori Iwatani
Publication date 2013/02
Summary We examined the effects of pralidoxime (PAM) salts, a medicine used to treat organophosphorus poisoning, on clinical laboratory test results for the first time. The addition of PAM iodide or potassium iodide, but not of PAM chloride or potassium chloride, to blood samples increased the GLU values measured by one POCT meter and four SMBG meters using the enzyme electrode method. PAM iodide or PAM chloride affected the values measured at 340 nm by an autoanalyzer in clinical laboratory tests.