ニシマツ　シンイチロウ   Shinichiro Nishimatsu   西松　伸一郎    所属   川崎医科大学  医学部 一般教養　自然科学    職種   教授
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Expression of Tbx20 RNA during chick heart development.
掲載誌名	正式名：Developmental dynamics : an official publication of the American Association of Anatomists 略　 称：Dev Dyn ISSNコード：10588388
巻・号・頁	230(3),pp.576-580
著者・共著者	Yamagishi Toshiyuki, Nakajima Yuji, Nishimatsu Shin-ichiro, Nohno Tsutomu, Ando Katsumi, Nakamura Hiroaki
発行年月	2004/07
概要	The T-box gene family encodes a set of transcription factors that are involved in various developmental processes. We isolated tbx20 gene from chick embryos and examined in detail its expression patterns during heart development. In situ hybridization showed that tbx20 was expressed in the lateral plate mesoderm and subsequently in the primitive heart tube. At stages of looped heart, tbx20 was localized in the outflow tract (OT) and atrioventricular (AV) canal, in which valvuloseptal endocardial cushion develops. At later stages, although tbx20 was expressed predominantly in the nascent right ventricle, transcripts of tbx20 were down-regulated in the left ventricle. These results suggest that tbx20 may play important roles in a variety of developmental processes in cardiogenesis, such as chamber-specification and septation.
DOI	10.1002/dvdy.20076
文献番号	15188442