ニシマツ　シンイチロウ   Shinichiro Nishimatsu   西松　伸一郎    所属   川崎医科大学  医学部 一般教養　自然科学    職種   教授
論文種別	総説
言語種別	英語
査読の有無	査読あり
表題	Activin as a cell differentiation factor.
掲載誌名	正式名：Progress in growth factor research 略　 称：Prog Growth Factor Res ISSNコード：09552235
巻・号・頁	2(2),pp.113-124
著者・共著者	Ueno Naoto, Nishimatsu Shin-ichiro, Murakami Kazuo
担当区分	2nd著者
発行年月	1990
概要	Activin, originally discovered as a polypeptide hormone that is capable of stimulating follicle-stimulating hormone secretion from pituitary cells in vitro, has recently been found to have a much wider range of biological activities. There are a number of reports of activin action as a cell differentiation factor on various types of cells rather than as a modulator of hormone secretion, as predicted initially, based on its structural similarity to transforming growth factor-beta. Studies of the distribution of activin and its receptor in a variety of tissues and its wide-ranging actions clearly illustrates its multifunctional properties. In particular, activin has been shown to be a potential regulator of early development of Xenopus laevis. Observation of activin effect in embryogenesis is of general importance to our understanding of the role of the family of growth factors in developmental processes.
DOI	10.1016/0955-2235(90)90027-H
文献番号	1966558