Shinichiro Nishimatsu
Department Kawasaki Medical School Kawasaki Medical School, Department of Natural Sciences, Position Professor |
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Article types | 原著 |
Language | English |
Peer review | Peer reviewed |
Title | Cloning of the rat angiotensin II type 2 receptor gene and identification of its functional promoter region. |
Journal | Formal name:Biochimica et Biophysica Acta - Gene Structure and Expression ISSN code:1674781 |
Volume, Issue, Page | 1262(2-3),pp.155-158 |
Author and coauthor | Kobayashi Shun-ichi, Ohnishi Junji, Nibu Yutaka, Nishimatsu Shin-ichiro, Umemura Satoshi, Ishii Masao, Murakami Kazuo, Miyazaki Hitoshi |
Publication date | 1995/06 |
Summary | We have cloned the rat angiotensin IT receptor type 2 (AT2) gene, whose physiological function remains unclear. Sequence analysis indicated that exons 1 and 2 exist in the 5'-untranslated region and the initiation codon ATG is located in exon 3. The 1.6-kb genomic fragment at positions - 1567 to +26 relative to the putative transcription start site was found to contain a functional promoter region using transient chloramphenicol acetyltransferase assay. This is the first report demonstrating the nucleotide sequence of the promoter region of this gene. |
DOI | 10.1016/0167-4781(95)00076-S |
Document No. | 7599191 |