ニシマツ　シンイチロウ   Shinichiro Nishimatsu   西松　伸一郎    所属   川崎医科大学  医学部 一般教養　自然科学    職種   教授
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	A carboxyl-terminal truncated version of the activin receptor mediates activin signals in early Xenopus embryos.
掲載誌名	正式名：FEBS letters 略　 称：FEBS Lett ISSNコード：00145793
巻・号・頁	312(2-3),pp.169-173
著者・共著者	Nishimatsu S, Iwao M, Nagai T, Oda S, Suzuki A, Asashima M, Murakami K, Ueno N
担当区分	筆頭著者
発行年月	1992/11
概要	The function of a carboxyl-terminal truncated version of the Xenopus activin receptor, encoded by a previously isolated gene XSTK2, was investigated in early embryos. The transcript corresponding to the truncated receptor gene was detected throughout embryonic development although the temporal expression pattern was different from that of an intact receptor. Injection of XSTK2 mRNA into early embryos resulted in the formation of a duplicated body axis. Mesoderm induction as evaluated by the activation of the alpha-actin gene in presumptive ectoderm (animal cap) treated with exogenous activin was significantly enhanced by the injection of XSTK2 mRNA. These results suggest that the truncated receptor is capable of transmitting the activin signal to the same extent as the native receptor.
DOI	10.1016/0014-5793(92)80928-A
文献番号	1330691