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イエキ ヨシアキ
Yoshiaki Ieki
家木 良彰 所属 川崎医科大学 医学部 臨床医学 眼科学１ 職種 准教授 |
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| 論文種別 | 原著 |
| 言語種別 | 英語 |
| 査読の有無 | 査読あり |
| 表題 | Changes in Choroidal Thickness and Structure Induced by 1% Atropine Instillation in Children With Hyperopic Anisometropic Amblyopia. |
| 掲載誌名 | 正式名：Journal of pediatric ophthalmology and strabismus 略 称：J Pediatr Ophthalmol Strabismus ISSNコード：19382405/01913913 |
| 掲載区分 | 国外 |
| 巻・号・頁 | 60(1),pp.39-45 |
| 著者・共著者 | Syunsuke Araki, Atsushi Miki, Katsutoshi Goto, Atsushi Fujiwara, Tsutomu Yamashita, Tsuyoshi Yoneda, Kazuko Haruishi, Yoshiaki Ieki, Junichi Kiryu, Goro Maehara, Kiyoshi Yaoeda |
| 発行年月 | 2023/01/30 |
| 概要 | PURPOSE:To investigate the effects of 1% atropine eye drops on the choroidal thickness and structure of amblyopic and fellow eyes in children with hyperopic anisometropic amblyopia.METHODS:This study included 16 children with hypermetropic anisometropic amblyopia. All patients received 1% atropine eye drops in both eyes twice a day for 7 days. In the subfoveal choroidal region, choroidal thickness, total choroidal area, luminal area, and stromal area were measured quantitatively using swept-source optical coherence tomography. The choroidal parameters of the amblyopic and fellow eyes were compared between the baseline and atropine conditions.RESULTS:There were no significant differences in all choroidal parameters of the amblyopic eye between baseline and atropine conditions. However, the subfoveal choroidal thickness in the fellow eye was significantly higher for the atropine condition than the baseline condition. This change was accompanied by a significant increase in both the luminal and stromal areas of the choroid. The median differences of subfoveal choroidal thickness between the conditions were larger for the fellow eye (6.46%) than the amblyopic eye (0.26%).CONCLUSIONS:The choroidal structural change induced by 1% atropine instillation was smaller for the amblyopic eye than the fellow eye in children with hyperopic anisometropic amblyopia. Mechanisms of choroidal thickness changes could be inhibited in amblyopic eyes. [J Pediatr Ophthalmol Strabismus. 2023;60(1):39-45.]. |
| DOI | 10.3928/01913913-20220216-03 |
| PMID | 35446189 |