マスダ ヨシキ   Yoshiki Masuda
  益田 芳樹
   所属   川崎医療福祉大学  医療福祉学部 臨床心理学科
   職種   特任教授
論文種別 原著
言語種別 英語
査読の有無 査読あり
表題 Toward understanding the morphogenesis of siliceous spicules in freshwater sponge: Differential mRNA expression of spicule-type-specific silication genes in Ephydatia fluviatilis.
掲載誌名 正式名:Developmental dynamics : an official publication of the American Association of Anatomists
略  称:Dev Dyn
ISSNコード:10588388
巻・号・頁 237(10),3024-3039頁
著者・共著者 Mohri Kurato, Nakatsukasa Mikiko, Masuda Yoshiki, Agata Kiyokazu, Funayama Noriko
発行年月 2008/10
概要 Siliceous spicules of sponges are morphologically diverse and provide good models for understanding the morphogenesis of biomineralized products. The silica deposition enzyme silicatein is a component of siliceous spicules of sponges and its thought to be the key molecule determining the morphology of spicules. Here, we focused on the silicateins of the freshwater sponge Ephydatia fluviatilis, which has two types of morphologically and functionally different spicules, called megascleres and gemmoscleres. We isolated six isoforms of silicateins and examined their mRNA expression in the cells producing megascleres and gemmoscleres. The spicule-type-specific mRNA expression of these isoforms and differential expression during spicule development suggest that the characteristic morphology of spicules is due to the specific properties and combinatory functions of silicatein isoforms.
DOI 10.10021dvdy.21708