Tomoharu Tokutomi    Department   Kawasaki Medical School  Kawasaki Medical School, Department of Pediatrics,    Position   Professor with Special Assignment
Article types	原著
Language	English
Peer review	Peer reviewed
Title	Characteristic profile of intestinal microflora in Kawasaki disease
Journal	Formal name：ACTA PAEDIATRICA ISSN code：0803-5253
Publisher	TAYLOR & FRANCIS AS
Volume, Issue, Page	91(7),pp.783-788
Author and coauthor	S Takeshita,Kobayashi, I,Y Kawamura,T Tokutomi,Sekine, I
Publication date	2002
Summary	To investigate whether the ecology of the intestinal microflora may change in the acute phase of Kawasaki disease (KD), the distribution pattern was studied of common micro-organisms in feces from 20 patients with KD, 20 patients with acute febrile diseases (disease control) and 20 healthy children. KD patients had a significantly lower (p < 0.001) incidence of Lactobacillus (2/20, 10%) than disease control patients (16/20, 80%) and healthy children (14/20, 70%). KD patients had no significant incidences of other microbial genera, compared with both disease control and healthy children. Conclusion: The results suggest that a lack or loss of the beneficial Lactobacillus genus in the enteric microflora may occur during the acute phase of KD.