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Tomoharu Tokutomi
Department Kawasaki Medical School Kawasaki Medical School, Department of Pediatrics, Position Professor with Special Assignment |
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| Article types | 原著 |
| Language | English |
| Peer review | Peer reviewed |
| Title | Standard-dose and short-term corticosteroid therapy in immunoglobulin-resistant Kawasaki disease. |
| Journal | Formal name：Clinical pediatrics ISSN code：0009-9228 |
| Domestic / Foregin | Foregin |
| Publisher | WESTMINSTER PUBL INC |
| Volume, Issue, Page | 44(5),pp.423-6 |
| Author and coauthor | Seiichiro Takeshita,Youichi Kawamura,Keigo Nakatani,Hiroshi Tsujimoto,Tomoharu Tokutomi |
| Publication date | 2005/06 |
| Summary | Six patients with Kawasaki disease (KD) were treated with prednisolone (1 to 2 mg/kg/day) for 3 days (from days 10 to 12 after the onset of the illness) after apparently unsuccessful treatment with intravenous immunoglobulin (IVIG, 2 g/kg/dose and additional 1 g/kg/dose). Five patients responded immediately to the first course of prednisolone infusion. One patient failed to respond to the first course of prednisolone therapy, but he did respond to the second 3-day course of therapy. None of the patients demonstrated a further progression of coronary artery dilatation or any adverse effects. Standard-dose and short-term corticosteroid therapy therefore appears to be a safe and effective treatment for patients with IVIG-resistant KD. |
| PMID | 15965549 |