Atsushi Higaki    Department   Kawasaki Medical School  Kawasaki Medical School, Department of Radiology, Division of Diagnostic Radiology,    Position   Assistant Professor
Article types	原著
Language	English
Peer review	Peer reviewed
Title	Potential clinical factors affecting hepatobiliary enhancement at Gd-EOB-DTPA-enhanced MR imaging.
Journal	Formal name：Magn Reson Imaging Abbreviation：Magn Reson Imaging
Domestic / Foregin	Foregin
Volume, Issue, Page	30(5),pp.689-693
Author and coauthor	Higaki Atsushi, Tamada Tsutomu, Sone Teruki, Kanki Akihiko, Sato Tomohiro, Tanimoto Daigo, Higashi Hiroki, Ito Katsuyoshi
Authorship	Lead author
Publication date	2012/06
Summary	The objective was to clarify the clinical factors that might affect the degree of hepatic parenchymal enhancement at gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance (MR) imaging. The presence or absence of chronic liver disease (P=.002), ascites (P=.005) and splenomegaly (P=.027), and the values of prothrombin activity (P=.008), total bilirubin (T-Bil) (P=.001), albumin (P=.001), aspartate aminotransferase (AST) (P=.002) and cholinesterase (P=.007) were significantly correlated with the RE of liver parenchyma at 20 min HP. Among these parameters, increases of T-Bil (P=.011 to .028) and AST (P=.018 to .049) were predictors of decreased hepatic parenchymal enhancement. Hepatic parenchymal enhancement of Gd-EOB-DTPA was affected by various clinical parameters. Impaired hepatobiliary enhancement may be predicted by routine biochemical tests, such as T-Bil and AST.